Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jennifer J. McGhee"'
Publikováno v:
World Journal of Stem Cells. 12:35-54
BACKGROUND: Keratoconus is a degenerative corneal disease characterised by aberrant cell behaviour and loss of matrix that can result in vision loss. Cells extracted from peripheral corneas can form stem cell-enriched spheres, which have shown the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f521cdade5aa5d84cc35e0d8a9ea702f
https://doi.org/10.4252/wjsc.v12.i1.35
https://doi.org/10.4252/wjsc.v12.i1.35
Autor:
Ye Li, Stephanie U-Shane Huang, Himanshu Wadhwa, Jeremy J Mathan, Jennifer J. McGhee, Salim Ismail, Trevor Sherwin, Jinny J. Yoon
Publikováno v:
Essentials in Ophthalmology ISBN: 9783030013035
Corneal cells isolated from the peripheral cornea and limbus can be cultured in vitro under sphere-forming conditions which enrich for stem and progenitor cells. These stem cell-enriched spheres represent a mixed population of cells comprising epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb3a2f01bcccf033eccbe16126299d34
https://doi.org/10.1007/978-3-030-01304-2_21
https://doi.org/10.1007/978-3-030-01304-2_21
Autor:
Bert van der Werf, Ye Li, Trevor Sherwin, Salim Ismail, Jennifer J. McGhee, Nikita Noord, Himanshu Wadhwa
Publikováno v:
Experimental Eye Research. 202:108301
Keratoconus is primarily an anterior corneal disorder of unclear aetiology. Stem cells may play a role in the perpetuation of keratoconus, although this has yet to be definitively established. Sphere-forming cells from normal human donor corneas have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4af12bb39fa31d85b1c5f959d05450
https://doi.org/10.1016/j.exer.2020.108301
https://doi.org/10.1016/j.exer.2020.108301
Autor:
Charles N J McGhee, Peter J. Wilson, Ommega Internationals, Salim Ismail, Jeremy J Mathan, Trevor Sherwin, Jennifer J. McGhee
Publikováno v:
Journal of Stem Cell and Regenerative Biology. 2:1-7
The human cornea requires a smooth, transparent, robust and renewable surface to maintain its key optical and protective functions. The corneal epithelium is maintained by a local population of “stem cells”, which although not truly pluripotent,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db35c363c7b183a84e3579a5660210b
https://doi.org/10.15436/2741-0598.16.010
https://doi.org/10.15436/2741-0598.16.010
Publikováno v:
Cell Biology International. 39:1274-1287
The cornea is the initial refractive interface of the eye. Its transparency is critical for clear vision and is maintained by stem cells which also act to repair injury inflicted by external insults, such as chemical and thermal burns. Damage to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72cc192783c1cb939a03a02272f56f54
https://doi.org/10.1002/cbin.10501
https://doi.org/10.1002/cbin.10501
Publikováno v:
Bio Protoc
Stem and progenitor cells isolated from human limbal tissue can be cultured in vitro as spheres. These spheres have potential for use as transplantable elements for the repopulation of corneal tissue ( Mathan et al., 2016 ). Herein we describe the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0134a3459f535da765bd7dbbe6366a7a
https://doi.org/10.21769/bioprotoc.2412
https://doi.org/10.21769/bioprotoc.2412
Autor:
Jing A. Chen, Alex Brebner, C.-Y. Chang, Angela Lim, Jennifer J. McGhee, Cameron J. Fraser, Carol Ann Greene, Trevor Sherwin, Colin R. Green, Dasha E. Nelidova
Publikováno v:
Experimental Cell Research. 322:122-132
Cells thought to be stem cells isolated from the cornea of the eye have been shown to exhibit neurogenic potential. We set out to uncover the identity and location of these cells within the cornea and to elucidate their neuronal protein and gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b0932ef7dbd7adcc2dff9da8a2018a
https://doi.org/10.1016/j.yexcr.2013.12.013
https://doi.org/10.1016/j.yexcr.2013.12.013
Publikováno v:
Keratoconus ISBN: 9783319438795
Histopathology has long been used to confirm the diagnosis of keratoconus and to determine the extent of disease progression in tissue post-corneal transplant. We examine here how modern advances in histopathology have informed the pathology of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69950658ee26cdffedbcbefd8a72f7fc
https://doi.org/10.1007/978-3-319-43881-8_4
https://doi.org/10.1007/978-3-319-43881-8_4
Publikováno v:
Cell Biology International. 37:949-960
Sphere-forming cells from peripheral cornea represent a potential source of progenitor cells for treatment of corneal degenerative diseases. Control of cellular repopulation on transplantable substrates is important to prevent uncontrolled growth in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4adbfefe4903901ca655e82a669c544
https://doi.org/10.1002/cbin.10119
https://doi.org/10.1002/cbin.10119
Sphere-forming cells from peripheral cornea demonstrate the ability to repopulate the ocular surface
Publikováno v:
Stem Cell Research & Therapy
Background The limbus forms the outer rim of the cornea at the corneoscleral junction and harbours a population of stem cells for corneal maintenance. Injuries to the limbus, through disease or accidents such as chemical injuries or burns, may lead t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4111ddcdd5e79cc02f3b1c49f7ad53
https://pubmed.ncbi.nlm.nih.gov/27250558
https://pubmed.ncbi.nlm.nih.gov/27250558