Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jennifer J. Klein"'
Autor:
Jennifer J. Klein, Nancy C. Baker, Daniel H. Foil, Kimberley M. Zorn, Fabio Urbina, Ana C. Puhl, Sean Ekins
Publikováno v:
ACS Omega, Vol 6, Iss 4, Pp 3186-3193 (2021)
Externí odkaz:
https://doaj.org/article/09bfecdc1ddf47c1980ccd2b606b4616
Autor:
Jennifer J. Klein, Nancy C. Baker, Daniel H. Foil, Kimberley M. Zorn, Fabio Urbina, Ana C. Puhl, Sean Ekins
Publikováno v:
ACS Omega, Vol 6, Iss 24, Pp 16253-16253 (2021)
Externí odkaz:
https://doaj.org/article/00b198b71baf4bafb22fd3f3eb344f93
Autor:
Kimberley M. Zorn, Anthony J. Hickey, Alex M. Clark, Ana C. Puhl, Jennifer J. Klein, Daniel P. Russo, Sean Ekins, Thomas J. Lane
Publikováno v:
Nat Mater
A variety of machine learning methods such as naive Bayesian, support vector machines and more recently deep neural networks are demonstrating their utility for drug discovery and development. These leverage the generally bigger datasets created from
Autor:
Ana C. Puhl, Kimberley M. Zorn, Daniel H. Foil, Nancy C. Baker, Sean Ekins, Fabio L. Urbina, Jennifer J. Klein
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 4, Pp 3186-3193 (2021)
ACS Omega, Vol 6, Iss 4, Pp 3186-3193 (2021)
Rare diseases impact hundreds of millions of individuals worldwide. However, few therapies exist to treat the rare disease population because financial resources are limited, the number of patients affected is low, bioactivity data is often nonexiste
Autor:
Eni Minerali, Anthony J. Hickey, Patricia A Vignaux, Jennifer J. Klein, Tammy M. Havener, Edward Anderson, Ana C. Puhl, Sean Ekins
Publikováno v:
Molecular Genetics and Metabolism. 132:S88-S89
Autor:
Ana C. Puhl, Kimberley M. Zorn, Daniel H. Foil, Sean Ekins, Fabio L. Urbina, Nancy C. Baker, Jennifer J. Klein
Publikováno v:
ACS Omega, Vol 6, Iss 24, Pp 16253-16253 (2021)
Autor:
Nancy C. Baker, Sean Ekins, Daniel H. Foil, Jennifer J. Klein, Ana Puhl Rubio, Kimberly M. Zorn
Publikováno v:
Molecular Genetics and Metabolism. 129:S90-S91
Autor:
Heather Flanagan-Steet, N. Matthew Ellinwood, Jennifer J. Klein, Alessandra d'Azzo, Sara S. Cathey, Thomas Braulke, Jenny Noble, Joshua A. Stern, Terri L. Klein, Allison M. Bradbury, Richard Steet
Publikováno v:
Molecular Genetics and Metabolism. 132:S58
Autor:
Patricia A Vignaux, Daniel H. Foil, Jennifer J. Klein, Ana C. Puhl, Sean Ekins, Kimberley M. Zorn
Publikováno v:
Molecular Genetics and Metabolism. 129:S132
Autor:
Alex M. Clark, Kimberley M. Zorn, Daniel P. Russo, Jennifer J. Klein, Sean Ekins, Nancy C. Baker, Ana Puhl Rubio
Publikováno v:
Molecular Genetics and Metabolism. 126:S86
We have recently stressed the need to scale and “industrialize” rare disease drug discovery. Finding information on compounds relevant to rare diseases across the hundreds of available databases is a complex challenge, even for experts and the li