Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jennifer J. Hofmann"'
Autor:
Colin Niaudet, Jennifer J Hofmann, Maarja A Mäe, Bongnam Jung, Konstantin Gaengel, Michael Vanlandewijck, Elisabet Ekvärn, M Dolores Salvado, Annika Mehlem, Sahar Al Sayegh, Liqun He, Thibaud Lebouvier, Marco Castro-Freire, Kan Katayama, Kjell Hultenby, Christine Moessinger, Philip Tannenberg, Sara Cunha, Kristian Pietras, Bàrbara Laviña, JongWook Hong, Tove Berg, Christer Betsholtz
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137949 (2015)
Despite its known expression in both the vascular endothelium and the lung epithelium, until recently the physiological role of the adhesion receptor Gpr116/ADGRF5 has remained elusive. We generated a new mouse model of constitutive Gpr116 inactivati
Externí odkaz:
https://doaj.org/article/6f2f517b62c14130b740db03e8f5de3c
Autor:
Faith Hall-Glenn, R Andrea De Young, Bau-Lin Huang, Ben van Handel, Jennifer J Hofmann, Tom T Chen, Aaron Choi, Jessica R Ong, Paul D Benya, Hanna Mikkola, M Luisa Iruela-Arispe, Karen M Lyons
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30562 (2012)
CCN2/Connective Tissue Growth Factor (CTGF) is a matricellular protein that regulates cell adhesion, migration, and survival. CCN2 is best known for its ability to promote fibrosis by mediating the ability of transforming growth factor β (TGFβ) to
Externí odkaz:
https://doaj.org/article/c9188197a81f442bb161d3ab4a6bcd26
Autor:
Khayrun Nahar, Guillem Genové, Annika Keller, Michael Vanlandewijck, Bàrbara Laviña, Maarja Andaloussi Mäe, Jennifer J. Hofmann, Liqun He, Christer Betsholtz, Giacomo Bertuzzi, Elisabeth Raschperger, Tian Li, Annika Dalheim
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Diabetes mellitus is associated with cognitive impairment and various central nervous system pathologies such as stroke, vascular dementia, or Alzheimer’s disease. The exact pathophysiology of these conditions is poorly understood. Recent reports s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd25babaf3b654cd9bc8b5ab39804ab8
https://www.zora.uzh.ch/id/eprint/160410/
https://www.zora.uzh.ch/id/eprint/160410/
Autor:
Karin Leander, Bruna Gigante, Angela Silveira, Anders Hamsten, Christer Betsholtz, Husain A. Talukdar, Hassan Foroughi Asl, Ming-Mei Shang, Cecilia Cedergren, Tom Michoel, Eric E. Schadt, Torbjörn Ivert, Arno Ruusalepp, Johan Björkegren, Josefin Skogsberg, Ulf de Faire, Jennifer J. Hofmann, Rajeev K. Jain, Colin Niaudet, Olle Melander, Aránzazu Rossignoli
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Objective— Using a multi-tissue, genome-wide gene expression approach, we recently identified a gene module linked to the extent of human atherosclerosis. This atherosclerosis module was enriched with inherited risk for coronary and carotid artery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f55280e03430e025ddd73bfbed322c
https://doi.org/10.1161/atvbaha.113.302709
https://doi.org/10.1161/atvbaha.113.302709
Autor:
Annika Keller, Maarja Andaloussi Mäe, Thibaud Lebouvier, Bongnam Jung, Elisabeth Raschperger, Jennifer J. Hofmann, Liqun He, Michael Vanlandewijck, Koji Ando, Christer Betsholtz
Publikováno v:
Scientific Reports
Pericytes, the mural cells of blood microvessels, regulate microvascular development and function and have been implicated in many brain diseases. However, due to a paucity of defining markers, pericyte identification and functional characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bebd71de64fa1d4c4412327ed427db5
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307265
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307265
Autor:
Zaverio M. Ruggeri, Alona Merkulova, Jennifer J. Hofmann, Alessandro Zarpellon, David J. Shields, Eric A. Murphy, Sara M. Weis, Lea Scheppke, Tatiana V. Byzova, David A. Cheresh, M. Luisa Iruela-Arispe
Publikováno v:
Blood. 119:2149-2158
Vascular development and angiogenesis initially depend on endothelial tip cell invasion, which is followed by a series of maturation steps, including lumen formation and recruitment of perivascular cells. Notch ligands expressed on the endothelium an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29158cde26864e70f48815fbb8db701
https://doi.org/10.1182/blood-2011-04-348706
https://doi.org/10.1182/blood-2011-04-348706
Autor:
M. Luisa Iruela-Arispe, Kevin C. Chen, Jennifer J. Hofmann, Judith C. Gasson, Timothy C. Cox, Ryan M. Ponec, Ann C. Zovein, Kirsten A. Turlo, Maureen Lynch
Publikováno v:
Blood
The vitelline artery is a temporary structure that undergoes extensive remodeling during midgestation to eventually become the superior mesenteric artery (also called the cranial mesenteric artery, in the mouse). Here we show that, during this remode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa4907603177f6d31a8a56291b5765f
https://doi.org/10.1182/blood-2010-04-279497
https://doi.org/10.1182/blood-2010-04-279497
Autor:
Per Lindblom, Jennifer J. Hofmann, Li-Kun Phng, Janet Rossant, Elisabet Wallgard, Mattias Kalén, Jackelyn A. Alva, Leigh Coultas, Linda Karlsson, Christer Betsholtz, Nicholas Gaiano, Keejung Yoon, Holger Gerhardt, M. Luisa Iruela-Arispe, Ann Katrin Nilsson, Mats Hellström
Publikováno v:
Nature. 445:776-780
In sprouting angiogenesis, specialized endothelial tip cells lead the outgrowth of blood-vessel sprouts towards gradients of vascular endothelial growth factor (VEGF)-A. VEGF-A is also essential for the induction of endothelial tip cells, but it is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e6864165328a3d48a1a9f4b87247548
https://doi.org/10.1038/nature05571
https://doi.org/10.1038/nature05571
Autor:
M. Luisa Iruela-Arispe, Ann C. Zovein, Jackelyn A. Alva, Jennifer J. Hofmann, Arnaud Monvoisin, Timothy F. Lane
Publikováno v:
Developmental Dynamics. 235:3413-3422
To introduce temporal control in genetic experiments targeting the endothelium, we established a mouse line expressing tamoxifen-inducible Cre-recombinase (Cre-ERT2) under the regulation of the vascular endothelial cadherin promoter (VECad). Specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fb5fb2d108cc94a54c8468cf4eb595
https://doi.org/10.1002/dvdy.20982
https://doi.org/10.1002/dvdy.20982
Autor:
Carsten Rudat, Matteo Pellegrini, Marlin Touma, Jennifer J. Hofmann, Carmen M. Warren, Rannar Airik, Karen M. Lyons, Andreas Kispert, Jing Lu, M. Luisa Iruela-Arispe, Gerry Weinmaster, Yibin Wang, Anaïs Briot, Artur Jaroszewicz
Publikováno v:
Developmental cell, vol 31, iss 6
Briot, A; Jaroszewicz, A; Warren, CM; Lu, J; Touma, M; Rudat, C; et al.(2014). Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental Cell, 31(6), 707-721. doi: 10.1016/j.devcel.2014.11.023. UCLA: Retrieved from: http://www.escholarship.org/uc/item/66x666mp
Briot, A; Jaroszewicz, A; Warren, CM; Lu, J; Touma, M; Rudat, C; et al.(2014). Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental Cell, 31(6), 707-721. doi: 10.1016/j.devcel.2014.11.023. UCLA: Retrieved from: http://www.escholarship.org/uc/item/66x666mp
© 2014 Elsevier Inc. Acquisition and maintenance of vascular smooth muscle fate are essential for the morphogenesis and function of the circulatory system. Loss of contractile properties or changes in the identity of vascular smooth muscle cells (vS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf5b5f6939f14768a940371d445cdd6
https://escholarship.org/uc/item/66x666mp
https://escholarship.org/uc/item/66x666mp