Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Jennifer J. Couper"'
Autor:
Farid H. Mahmud, Antoine B. M. Clarke, Yesmino Elia, Jacqueline Curtis, Paul Benitez-Aguirre, Fergus J. Cameron, Scott T. Chiesa, Cheril Clarson, Jennifer J. Couper, Maria E. Craig, R. Neil Dalton, Denis Daneman, Elizabeth A. Davis, John E. Deanfield, Kim C. Donaghue, Timothy W. Jones, Sally M. Marshall, Andrew Neil, M. Loredana Marcovecchio
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Given limited data regarding the involvement of disadvantaged groups in paediatric diabetes clinical trials, this study aimed to evaluate the socioeconomic representativeness of participants recruited into a multinational clinical
Externí odkaz:
https://doaj.org/article/27ef85e4176541e7954e50dc16a4c90f
Autor:
Helena Oakey, Lynne C. Giles, Rebecca L. Thomson, Kim-Anh Lê Cao, Pat Ashwood, James D. Brown, Emma J. Knight, Simon C. Barry, Maria E. Craig, Peter G. Colman, Elizabeth A. Davis, Emma E. Hamilton-Williams, Leonard C. Harrison, Aveni Haynes, Ki Wook Kim, Kylie-Ann Mallitt, Kelly McGorm, Grant Morahan, William D. Rawlinson, Richard O. Sinnott, Georgia Soldatos, John M. Wentworth, Jennifer J. Couper, Megan A. S. Penno
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractBackground: The Environmental Determinants of Islet Autoimmunity (ENDIA) pregnancy-birth cohort investigates the developmental origins of type 1 diabetes (T1D), with recruitment between 2013 and 2019. ENDIA is the first study in the world wit
Externí odkaz:
https://doaj.org/article/4020f54528be4126a735e523a39a8616
Autor:
Ying Y. Wong, Jessica E. Harbison, Christopher M. Hope, Batjargal Gundsambuu, Katherine A. Brown, Soon W. Wong, Cheryl Y Brown, Jennifer J. Couper, Jimmy Breen, Ning Liu, Stephen M. Pederson, Maren Köhne, Kathrin Klee, Joachim Schultze, Marc Beyer, Timothy Sadlon, Simon C. Barry
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Epigenetic features such as DNA accessibility dictate transcriptional regulation in a cell type- and cell state- specific manner, and mapping this in health vs. disease in clinically relevant material is opening the door to new mechanistic i
Externí odkaz:
https://doaj.org/article/a56eda72cadc4472b5afe216794b04ff
Autor:
Alexandra J. Roth-Schulze, Megan A. S. Penno, Katrina M. Ngui, Helena Oakey, Esther Bandala-Sanchez, Alannah D. Smith, Theo R. Allnutt, Rebecca L. Thomson, Peter J. Vuillermin, Maria E. Craig, William D. Rawlinson, Elizabeth A. Davis, Mark Harris, Georgia Soldatos, Peter G. Colman, John M. Wentworth, Aveni Haynes, Simon C. Barry, Richard O. Sinnott, Grant Morahan, Naiara G. Bediaga, Gordon K. Smyth, Anthony T. Papenfuss, Jennifer J. Couper, Leonard C. Harrison, on behalf of the ENDIA Study Group
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-21 (2021)
Abstract Background The gut microbiome changes in response to a range of environmental conditions, life events and disease states. Pregnancy is a natural life event that involves major physiological adaptation yet studies of the microbiome in pregnan
Externí odkaz:
https://doaj.org/article/253f5dc621044d0ea3730150c87cbbef
Autor:
Kelly J. McGorm, James D. Brown, Alison G. Roberts, Susan Greenbank, Daniella Brasacchio, Alyssa C. P. Sawyer, Helena Oakey, Peter G. Colman, Maria E. Craig, Elizabeth A. Davis, Georgia Soldatos, Rebecca L. Thomson, John M. Wentworth, Jennifer J. Couper, Megan A. S. Penno, on behalf of The ENDIA Study Group
Publikováno v:
Children, Vol 10, Iss 4, p 637 (2023)
Background: We sought research experiences of caregivers and their children were enrolled in the Environmental Determinants of Islet Autoimmunity (ENDIA) study. Methods: ENDIA is a pregnancy–birth cohort investigating early-life causes of type 1 di
Externí odkaz:
https://doaj.org/article/b922970066a649a6966b5b556b2f7a7b
Autor:
Christopher M. Hope, Dao Huynh, Ying Ying Wong, Helena Oakey, Griffith Boord Perkins, Trung Nguyen, Sabrina Binkowski, Minh Bui, Ace Y. L. Choo, Emily Gibson, Dexing Huang, Ki Wook Kim, Katrina Ngui, William D. Rawlinson, Timothy Sadlon, Jennifer J. Couper, Megan A. S. Penno, Simon C. Barry, on behalf of the ENDIA Study Group
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9129 (2021)
Background: Rural/remote blood collection can cause delays in processing, reducing PBMC number, viability, cell composition and function. To mitigate these impacts, blood was stored at 4 °C prior to processing. Viable cell number, viability, immune
Externí odkaz:
https://doaj.org/article/ccdd4da49d49433f9623a37c6b9e5e34
Autor:
William Rawlinson, Jason A Tye-Din, Simon Barry, Peter J Vuillermin, Leonard C Harrison, Georgia Soldatos, Maria E Craig, Elizabeth A Davis, Peter G Colman, Amanda Anderson, Emma Hamilton-Williams, Pat Ashwood, Tony Huynh, Rebecca L Thomson, Helena Oakey, Aveni Haynes, John M Wentworth, Bek Brittain, James D Brown, Dao Huynh, Ki-Wook Kim, Kelly J McGorm, Grant Morahan, Richard O Sinnott, Megan A S Penno, Jennifer J Couper
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 4 (2024)
Introduction The Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an ongoing Australian prospective cohort study investigating how modifiable prenatal and early-life exposures drive the development of islet autoimmunity and type 1 di
Externí odkaz:
https://doaj.org/article/6bea03044ba743979e6137da76e170a8
Autor:
Group, Kelly J. McGorm, James D. Brown, Alison G. Roberts, Susan Greenbank, Daniella Brasacchio, Alyssa C. P. Sawyer, Helena Oakey, Peter G. Colman, Maria E. Craig, Elizabeth A. Davis, Georgia Soldatos, Rebecca L. Thomson, John M. Wentworth, Jennifer J. Couper, Megan A. S. Penno, on behalf of The ENDIA Study Group on behalf of The ENDIA Study
Publikováno v:
Children; Volume 10; Issue 4; Pages: 637
Background: We sought research experiences of caregivers and their children were enrolled in the Environmental Determinants of Islet Autoimmunity (ENDIA) study. Methods: ENDIA is a pregnancy–birth cohort investigating early-life causes of type 1 di
Autor:
Naiara G. Bediaga, Alexandra L. Garnham, Gaetano Naselli, Esther Bandala-Sanchez, Natalie L. Stone, Joanna Cobb, Jessica E. Harbison, John M. Wentworth, Annette-G. Ziegler, Jennifer J. Couper, Gordon K. Smyth, Leonard C. Harrison
Publikováno v:
Diabetes
Type 1 diabetes in children is heralded by a preclinical phase defined by circulating autoantibodies to pancreatic islet antigens. How islet autoimmunity is initiated and then progresses to clinical diabetes remains poorly understood. Only one study
Publikováno v:
Pediatric Diabetes. 23:98-103
OBJECTIVE To assess whether introduction of Continuous Glucose Monitoring (CGM) at diagnosis of type 1 diabetes (T1D), leads to greater uptake and continuation at 12 and 24 months, in a population based paediatric diabetes clinic. RESEARCH DESIGN AND