Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Jennifer J. Brady"'
Autor:
Christopher W. Murray, Jennifer J. Brady, Mingqi Han, Hongchen Cai, Min K. Tsai, Sarah E. Pierce, Ran Cheng, Janos Demeter, David M. Feldser, Peter K. Jackson, David B. Shackelford, Monte M. Winslow
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
LKB1 tumour suppressor gene is frequently mutated in lung adenocarcinoma. Here the authors show that in genetically engineered mouse models of lung cancer Lkb1 restoration induces growth arrest and drives neoplastic cells toward a more differentiated
Externí odkaz:
https://doaj.org/article/fac054136b674b659d92c440e9e9e2b2
Autor:
Rosemary Dineen, Lucy-Ann Behan, Grainne Kelleher, Mark J. Hannon, Jennifer J. Brady, Bairbre Rogers, Brian G. Keevil, William Tormey, Diarmuid Smith, Christopher J. Thompson, Malachi J. McKenna, Wiebke Arlt, Paul M. Stewart, Amar Agha, Mark Sherlock
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal insufficiency. Enhance
Externí odkaz:
https://doaj.org/article/bf4aba1aa7d2468da0919f529f545f18
Autor:
Amy, Gillick, Jennifer J, Brady
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 61:e71-e73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43abd07dacbd1d2ff4013f439f54944
https://doi.org/10.1515/cclm-2022-0891
https://doi.org/10.1515/cclm-2022-0891
Autor:
Esme Dunne, Daniel O’Reilly, Claire A. Murphy, Caoimhe Howard, Grainne Kelleher, Thomas Suttie, Michael A. Boyle, Jennifer J. Brady, Ina Knerr, Afif El Khuffash
Publikováno v:
European Journal of Pediatrics. 181:3725-3732
Inborn errors of metabolism are an individually rare but collectively significant cause of mortality and morbidity in the neonatal period. They are identified by either newborn screening programmes or clinician-initiated targeted biochemical screenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ee7182fe8e8f0a2092344df8c6c93f
https://doi.org/10.1007/s00431-022-04588-4
https://doi.org/10.1007/s00431-022-04588-4
Autor:
Monte M. Winslow, Julien Sage, William J. Greenleaf, Anshul Kundaje, Matthias Preusser, Kwon-Sik Park, H. Christian Reinhardt, Anna Schmitt, Anna S. Berghoff, Christina S. Kong, Shirley Kwok, Jing Shan Lim, Nadine S. Jahchan, Jeffrey M. Granja, Youcef Ouadah, Jennifer J. Brady, Andrea C. Chaikovsky, Peyton G. Greenside, Sarah K. Denny, Dian Yang
table_S2_housekeeping_genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882ae08ad7ea889f544d07d349860272
https://doi.org/10.1158/2159-8290.22532191
https://doi.org/10.1158/2159-8290.22532191
Autor:
Monte M. Winslow, Pauline Chu, Christian A. Kunder, Rosanna K. Ma, Laura Andrejka, Rui Tang, Ian P. Winters, Chuan Li, Min K. Tsai, Jennifer J. Brady, Christopher W. Murray
Summary of gene sets generated from previously published analyses of the LKB1-deficient state in human lung adenocarcinoma cell lines and tumors as well as genetically engineered mouse models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180f5e1c5fca29afb931367a73caadfa
https://doi.org/10.1158/2159-8290.22532464
https://doi.org/10.1158/2159-8290.22532464
Autor:
Monte M. Winslow, Julien Sage, William J. Greenleaf, Anshul Kundaje, Matthias Preusser, Kwon-Sik Park, H. Christian Reinhardt, Anna Schmitt, Anna S. Berghoff, Christina S. Kong, Shirley Kwok, Jing Shan Lim, Nadine S. Jahchan, Jeffrey M. Granja, Youcef Ouadah, Jennifer J. Brady, Andrea C. Chaikovsky, Peyton G. Greenside, Sarah K. Denny, Dian Yang
All supplementary figures (S1-S17)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bbd3f1e44f1b89db6fba9a80eaf435
https://doi.org/10.1158/2159-8290.22532197
https://doi.org/10.1158/2159-8290.22532197
Autor:
Christopher W, Murray, Jennifer J, Brady, Mingqi, Han, Hongchen, Cai, Min K, Tsai, Sarah E, Pierce, Ran, Cheng, Janos, Demeter, David M, Feldser, Peter K, Jackson, David B, Shackelford, Monte M, Winslow
Publikováno v:
Nature communications. 13(1)
LKB1 is among the most frequently altered tumor suppressors in lung adenocarcinoma. Inactivation of Lkb1 accelerates the growth and progression of oncogenic KRAS-driven lung tumors in mouse models. However, the molecular mechanisms by which LKB1 cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f05149f18cc9f425b53de5db6893e2e
https://pubmed.ncbi.nlm.nih.gov/35228570
https://pubmed.ncbi.nlm.nih.gov/35228570
Autor:
Michael C. Bassik, Monte M. Winslow, Howard Y. Chang, M. Ryan Corces, David M. Feldser, Aubrey B Pierce, Pauline Chu, Jennifer J. Brady, William J. Greenleaf, Jeffrey M. Granja, Rui Tang, Sarah E. Pierce, Min K. Tsai
Metastasis is the leading cause of cancer-related deaths, enabling cancer cells to expand to secondary sites and compromise organ function1. Given that primary tumors and metastases often share the same constellation of driver mutations2–4, the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ede3fa805e1335a7d6adec40438be1
https://doi.org/10.1101/2021.03.29.437560
https://doi.org/10.1101/2021.03.29.437560
Publikováno v:
Journal of pediatric endocrinologymetabolism : JPEMReferences. 34(9)
Background The aim of this study was to describe the incidence and spectrum of early clinical presentations of congenital adrenal hyperplasia (CAH) in an unscreened population. Methods A national retrospective observational study was undertaken to id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8023f38cf12a394c70fececf0ed9d56
https://pubmed.ncbi.nlm.nih.gov/34167176
https://pubmed.ncbi.nlm.nih.gov/34167176