Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Jennifer J Westendorf"'
Autor:
Yuqian Yan, Jian An, Yinhui Yang, Di Wu, Yang Bai, William Cao, Linlin Ma, Junhui Chen, Zhendong Yu, Yundong He, Xin Jin, Yunqian Pan, Tao Ma, Shangqian Wang, Xiaonan Hou, Saravut John Weroha, R Jeffrey Karnes, Jun Zhang, Jennifer J Westendorf, Liguo Wang, Yu Chen, Wanhai Xu, Runzhi Zhu, Dejie Wang, Haojie Huang
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)
Abstract AKT‐mTOR and androgen receptor (AR) signaling pathways are aberrantly activated in prostate cancer due to frequent PTEN deletions or SPOP mutations. A clinical barrier is that targeting one of them often activates the other. Here, we demon
Externí odkaz:
https://doaj.org/article/fe77ca9d430249659565d1429f2f9aba
Autor:
David J Hinton, Meghan E McGee-Lawrence, Moonnoh R Lee, Hoi K Kwong, Jennifer J Westendorf, Doo-Sup Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88818 (2014)
Adenosine is known to regulate bone production and resorption in humans and mice. Type 1 equilibrative nucleoside transporter (ENT1) is responsible for the majority of adenosine transport across the plasma membrane and is ubiquitously expressed in bo
Externí odkaz:
https://doaj.org/article/2354df19d94f4c6ea264e4c3fc332f63
Autor:
Nathan W Cummins, Anna Klicpera, Amy M Sainski, Gary D Bren, Sundeep Khosla, Jennifer J Westendorf, Andrew D Badley
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24876 (2011)
Patients with HIV infection have decreased numbers of osteoblasts, decreased bone mineral density and increased risk of fracture compared to uninfected patients; however, the molecular mechanisms behind these associations remain unclear. We questione
Externí odkaz:
https://doaj.org/article/8d1ea0a6bb65496fac755409464d7227
Autor:
David F Razidlo, Tiffany J Whitney, Michelle E Casper, Meghan E McGee-Lawrence, Bridget A Stensgard, Xiaodong Li, Frank J Secreto, Sarah K Knutson, Scott W Hiebert, Jennifer J Westendorf
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11492 (2010)
Histone deacetylase (Hdac)3 is a nuclear enzyme that contributes to epigenetic programming and is required for embryonic development. To determine the role of Hdac3 in bone formation, we crossed mice harboring loxP sites around exon 7 of Hdac3 with m
Externí odkaz:
https://doaj.org/article/782d7d2bcd6441dc8442d80bda9aaaf9
Autor:
Amel Dudakovic, Sofia Jerez, Padmini J. Deosthale, Janet M. Denbeigh, Christopher R. Paradise, Martina Gluscevic, Pengfei Zan, Dana L. Begun, Emily T. Camilleri, Oksana Pichurin, Farzaneh Khani, Roman Thaler, Jane B. Lian, Gary S. Stein, Jennifer J. Westendorf, Lilian I. Plotkin, Andre J. van Wijnen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract High-throughput microRNA sequencing was performed during differentiation of MC3T3-E1 osteoblasts to develop working hypotheses for specific microRNAs that control osteogenesis. The expression data show that miR-101a, which targets the mRNAs
Externí odkaz:
https://doaj.org/article/f5c778c9a9e84a5d9acbf3c478897543
Publikováno v:
Sensors, Vol 23, Iss 4, p 1835 (2023)
The mechanical properties of biological tissues influence their function and can predict degenerative conditions before gross histological or physiological changes are detectable. This is especially true for structural tissues such as articular carti
Externí odkaz:
https://doaj.org/article/f148426ae4b74f4d84a72238941e8635
Autor:
Wanhai Xu, Haojie Huang, Runzhi Zhu, Benyi Li, Jennifer J. Westendorf, Manish Kohli, R. Jeffrey Karnes, Jun Zhang, Michael Hinten, Yunqian Pan, Linlin Ma, Jiaxiang Chen, Yu Zhao, Yundong He, Yang Bai, Yinhui Yang
In panel A, RUNX2 knockdown in C4-2B cells completely abolished NVP-BEZ235-induced inhibition of expression of CYP11A1 and CYP17A1 mRNA. In panel B, ectopic expression of FOXO1-A3 failed to induce overt changes in RUNX2 expression at both mRNA and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3217963300c1fa21701841bcdcf2ad2e
https://doi.org/10.1158/1078-0432.22465451
https://doi.org/10.1158/1078-0432.22465451
Autor:
Wanhai Xu, Haojie Huang, Runzhi Zhu, Benyi Li, Jennifer J. Westendorf, Manish Kohli, R. Jeffrey Karnes, Jun Zhang, Michael Hinten, Yunqian Pan, Linlin Ma, Jiaxiang Chen, Yu Zhao, Yundong He, Yang Bai, Yinhui Yang
Purpose: Intratumoral androgen synthesis (IAS) is a key mechanism promoting androgen receptor (AR) reactivation and antiandrogen resistance in castration-resistant prostate cancer (CRPC). However, signaling pathways driving aberrant IAS remain poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38932bd53aefc094ad689c8884643a7e
https://doi.org/10.1158/1078-0432.c.6526022.v1
https://doi.org/10.1158/1078-0432.c.6526022.v1
Autor:
Wanhai Xu, Haojie Huang, Runzhi Zhu, Benyi Li, Jennifer J. Westendorf, Manish Kohli, R. Jeffrey Karnes, Jun Zhang, Michael Hinten, Yunqian Pan, Linlin Ma, Jiaxiang Chen, Yu Zhao, Yundong He, Yang Bai, Yinhui Yang
File containing Supplementary Materials and Methods, references for Supplementary Materials and Methods, and Supplementary Figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aa427cc77561bfa292e0453fec2764
https://doi.org/10.1158/1078-0432.22465433.v1
https://doi.org/10.1158/1078-0432.22465433.v1
Autor:
Shizhen Zhu, John M. Maris, Jennifer J. Westendorf, Hu Li, Jan M. van Deursen, A. Thomas Look, S. John Weroha, Komal S. Rathi, Gina L. Razidlo, Alexander Meves, Julia S. Lehman, Jorge Torres-Mora, Karen Fritchie, Ting Tao, Shuning He, Shuai Li, Janine H. van Ree, Xiaonan Hou, Cassie J. Howe, Zuag Paj Her, Taylor M. Levee, Choong Yong Ung, Jo Lynne Rokita, Erin N. Dankert Eggum, Cheng Zhang, Gonzalo Lopez, Kok Siong Yeo, Zhiwei Dong
SUPPLEMENTARY TABLES, FIGURES AND FIGURE LEGENDS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438549837a6a26ad2aa79d8ab5c9d0bb
https://doi.org/10.1158/0008-5472.22429665
https://doi.org/10.1158/0008-5472.22429665