Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jennifer J McCann"'
Autor:
Matthew J Schiewer, Amy C Mandigo, Nicolas Gordon, Fangjin Huang, Sanchaika Gaur, Renée de Leeuw, Shuang G Zhao, Joseph Evans, Sumin Han, Theodore Parsons, Ruth Birbe, Peter McCue, Christopher McNair, Saswati N Chand, Ylenia Cendon‐Florez, Peter Gallagher, Jennifer J McCann, Neermala Poudel Neupane, Ayesha A Shafi, Emanuela Dylgjeri, Lucas J Brand, Tapio Visakorpi, Ganesh V Raj, Costas D Lallas, Edouard J Trabulsi, Leonard G Gomella, Adam P Dicker, Wm. Kevin Kelly, Benjamin E Leiby, Beatrice Knudsen, Felix Y Feng, Karen E Knudsen
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp 1-20 (2018)
Abstract PARP‐1 holds major functions on chromatin, DNA damage repair and transcriptional regulation, both of which are relevant in the context of cancer. Here, unbiased transcriptional profiling revealed the downstream transcriptional profile of P
Externí odkaz:
https://doaj.org/article/044d966fd25b4793a1abaa4247be3583
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair
Autor:
Ayesha A. Shafi, Chris M. McNair, Jennifer J. McCann, Mohammed Alshalalfa, Anton Shostak, Tesa M. Severson, Yanyun Zhu, Andre Bergman, Nicolas Gordon, Amy C. Mandigo, Saswati N. Chand, Peter Gallagher, Emanuela Dylgjeri, Talya S. Laufer, Irina A. Vasilevskaya, Matthew J. Schiewer, Michael Brunner, Felix Y. Feng, Wilbert Zwart, Karen E. Knudsen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Cryptochrome 1 (CRY1) is a transcriptional coregulator associated with the circadian clock. Here the authors reveal that CRY1 is hormone-regulated, stabilized by genomic insult, and promotes DNA repair and cell survival through temporal transcription
Externí odkaz:
https://doaj.org/article/5fde36ecfc1c40aebc4b7e899820784f
Autor:
Karen E. Knudsen, Johann S. de Bono, Chris M. McNair, Matthew J. Schiewer, Irina A. Vasilevskaya, Galina Semenova, Emanuela Dylgjeri, Lewis Gallagher, Denisa Bogdan, Talya S. Laufer, Wei Yuan, Jennifer J. McCann, Ayesha A. Shafi, Amy C. Mandigo
Supplemental Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ea22f08e386e51a120b18c4fd559e4
https://doi.org/10.1158/0008-5472.22569198.v1
https://doi.org/10.1158/0008-5472.22569198.v1
Autor:
Karen E. Knudsen, Johann S. de Bono, Chris M. McNair, Matthew J. Schiewer, Irina A. Vasilevskaya, Galina Semenova, Emanuela Dylgjeri, Lewis Gallagher, Denisa Bogdan, Talya S. Laufer, Wei Yuan, Jennifer J. McCann, Ayesha A. Shafi, Amy C. Mandigo
Supplemental Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a66aa4b44bfe9a3f4da11601721527
https://doi.org/10.1158/0008-5472.22569192.v1
https://doi.org/10.1158/0008-5472.22569192.v1
Autor:
Karen E. Knudsen, Johann S. de Bono, Chris M. McNair, Matthew J. Schiewer, Irina A. Vasilevskaya, Galina Semenova, Emanuela Dylgjeri, Lewis Gallagher, Denisa Bogdan, Talya S. Laufer, Wei Yuan, Jennifer J. McCann, Ayesha A. Shafi, Amy C. Mandigo
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c755549da80ac0026ccc3807e2f495e
https://doi.org/10.1158/0008-5472.22569186.v1
https://doi.org/10.1158/0008-5472.22569186.v1
Autor:
Karen E. Knudsen, Johann S. de Bono, Chris M. McNair, Matthew J. Schiewer, Irina A. Vasilevskaya, Galina Semenova, Emanuela Dylgjeri, Lewis Gallagher, Denisa Bogdan, Talya S. Laufer, Wei Yuan, Jennifer J. McCann, Ayesha A. Shafi, Amy C. Mandigo
Supplemental Figure 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8454e63524029e25f65b4554d9fc5705
https://doi.org/10.1158/0008-5472.22569189.v1
https://doi.org/10.1158/0008-5472.22569189.v1
Autor:
Karen E. Knudsen, Johann S. de Bono, Chris M. McNair, Matthew J. Schiewer, Irina A. Vasilevskaya, Galina Semenova, Emanuela Dylgjeri, Lewis Gallagher, Denisa Bogdan, Talya S. Laufer, Wei Yuan, Jennifer J. McCann, Ayesha A. Shafi, Amy C. Mandigo
The retinoblastoma tumor suppressor (RB) is a critical regulator of E2F-dependent transcription, controlling a multitude of protumorigenic networks including but not limited to cell-cycle control. Here, genome-wide assessment of E2F1 function after R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a960fdd84c15967028b80f4e661728
https://doi.org/10.1158/0008-5472.c.6567234.v1
https://doi.org/10.1158/0008-5472.c.6567234.v1
Autor:
Karen E. Knudsen, Dana Rathkopf, Kristin Hege, Ellen H. Filvaroff, Felix Y. Feng, Edouard J. Trabulsi, Costas D. Lallas, Leonard G. Gomella, Talya S. Laufer, Nicolas Gordon, Irina Vasilevskaya, Lucas J. Brand, Matthew J. Schiewer, Saswati N. Chand, Amy C. Mandigo, Jennifer J. McCann, Vishal Kothari, Renée de Leeuw, Benjamin E. Leiby, Ayesha A. Shafi, Peter A. McCue, Heather K. Raymon, Jonathan F. Goodwin, Christopher McNair, Emanuela Dylgjeri
Table S1, Primer sequences used for gene expression analysis. Table S2, PDE pathological characteristics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f045bd8eaec9dbd8f6d8824e4dc5038
https://doi.org/10.1158/1078-0432.22472514
https://doi.org/10.1158/1078-0432.22472514
Autor:
Karen E. Knudsen, William F. Ostrander, Lisa D. Berman-Booty, Steven B. McMahon, Timothy J. Stanek, Peter Gallagher, Randy S. Schrecengost, Matthew J. Schiewer, Amy C. Mandigo, Emanuela Dylgjeri, Christopher McNair, Ayesha A. Shafi, Neermala Poudel Neupane, Irina A. Vasilevskaya, Jennifer J. McCann
SF1: Analysis of USP22 expression with known drivers of disease progression; SF2: USP22 modulates DNA repair factors expression and survival after DNA damage; SF3: Genetically engineered mouse model of tumor-associated USP22 expression; SF4: The USP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022fe49665c7d77d32500f3538ae566b
https://doi.org/10.1158/0008-5472.22425430
https://doi.org/10.1158/0008-5472.22425430
Autor:
Karen E. Knudsen, Dana Rathkopf, Kristin Hege, Ellen H. Filvaroff, Felix Y. Feng, Edouard J. Trabulsi, Costas D. Lallas, Leonard G. Gomella, Talya S. Laufer, Nicolas Gordon, Irina Vasilevskaya, Lucas J. Brand, Matthew J. Schiewer, Saswati N. Chand, Amy C. Mandigo, Jennifer J. McCann, Vishal Kothari, Renée de Leeuw, Benjamin E. Leiby, Ayesha A. Shafi, Peter A. McCue, Heather K. Raymon, Jonathan F. Goodwin, Christopher McNair, Emanuela Dylgjeri
Supplementary Figures 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd9c0a3610db33cd876c4245dfb1047
https://doi.org/10.1158/1078-0432.22472517
https://doi.org/10.1158/1078-0432.22472517