Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jennifer Hyoje-Ryu Kenty"'
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100675- (2021)
Summary: Stem cell-derived beta cells (SC-β-cells) engrafted into mice serve as a pre-clinical model of diabetes. It is helpful to recover viable β cells following transplantation to perform tests on the graft. We developed a protocol to retrieve a
Externí odkaz:
https://doaj.org/article/93ce247db67f478f904ac808326f697a
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102371- (2021)
Human stem cell-derived beta (SC-β) cells are a candidate for cell replacement therapy for type 1 diabetes. Whilst refinements to the differentiation protocol have resulted in the production of SC-β cells that resemble adult beta cells, the unsolve
Externí odkaz:
https://doaj.org/article/8e08419b6abd4df89977b681f0d3664b
Autor:
Elad Sintov, Igor Nikolskiy, Victor Barrera, Jennifer Hyoje-Ryu Kenty, Alexander S. Atkin, Dario Gerace, Shannan J. Ho Sui, Kyle Boulanger, Douglas A. Melton
Publikováno v:
Stem Cell Reports. 17:1976-1990
Human embryonic stem cells (hESCs) provide opportunities for cell replacement therapy of insulin-dependent diabetes. Therapeutic quantities of human stem cell-derived islets (SC-islets) can be produced by directed differentiation. However, preventing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db802d975b1a3fb6889afa3299dc97fe
https://doi.org/10.1016/j.stemcr.2022.08.002
https://doi.org/10.1016/j.stemcr.2022.08.002
Autor:
Dario Gerace, Quan Zhou, Jennifer Hyoje-Ryu Kenty, Elad Sintov, Xi Wang, Kyle R Boulanger, Hongfei Li, Douglas A Melton
SummaryImmunological protection of transplanted stem cell-derived islet (SC-islet) cells is yet to be achieved without chronic immunosuppression or encapsulation. Existing genetic engineering approaches to produce hypoimmunogenic SC-islet cells have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd5e195f562ab80234f9423d144b2953
https://doi.org/10.1101/2022.05.09.487072
https://doi.org/10.1101/2022.05.09.487072
Autor:
Dario Gerace, Quan Zhou, Jennifer Hyoje-Ryu Kenty, Adrian Veres, Elad Sintov, Xi Wang, Kyle R. Boulanger, Hongfei Li, Douglas A. Melton
Publikováno v:
Cell reports. Medicine.
Immunological protection of transplanted stem cell-derived islet (SC-islet) cells is yet to be achieved without chronic immunosuppression or encapsulation. Existing genetic engineering approaches to produce immune-evasive SC-islet cells have so far s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00c53ec4c297d09bf35102c264380c3
https://pubmed.ncbi.nlm.nih.gov/36599351
https://pubmed.ncbi.nlm.nih.gov/36599351
Autor:
Elad Sintov, Igor Nikolskiy, Victor Barrera, Jennifer Hyoje-Ryu Kenty, Alexander S. Atkin, Dario Gerace, Shannan J. Ho Sui, Kyle Boulanger, Douglas A. Melton
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40845c9f3983a28f950a73ce968fc3e7
https://doi.org/10.2139/ssrn.4081520
https://doi.org/10.2139/ssrn.4081520
Publikováno v:
Stem Cell Research, Vol 53, Iss, Pp 102371-(2021)
Human stem cell-derived beta (SC-β) cells are a candidate for cell replacement therapy for type 1 diabetes. Whilst refinements to the differentiation protocol have resulted in the production of SC-β cells that resemble adult beta cells, the unsolve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312d37ad404d4af974ac7adfa44307ea
http://www.sciencedirect.com/science/article/pii/S1873506121002178
http://www.sciencedirect.com/science/article/pii/S1873506121002178