Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jennifer Huen"'
Autor:
Kamran Rizzolo, Jennifer Huen, Ashwani Kumar, Sadhna Phanse, James Vlasblom, Yoshito Kakihara, Hussein A. Zeineddine, Zoran Minic, Jamie Snider, Wen Wang, Carles Pons, Thiago V. Seraphim, Edgar Erik Boczek, Simon Alberti, Michael Costanzo, Chad L. Myers, Igor Stagljar, Charles Boone, Mohan Babu, Walid A. Houry
Publikováno v:
Cell Reports, Vol 20, Iss 11, Pp 2735-2748 (2017)
A comprehensive view of molecular chaperone function in the cell was obtained through a systematic global integrative network approach based on physical (protein-protein) and genetic (gene-gene or epistatic) interaction mapping. This allowed us to de
Externí odkaz:
https://doaj.org/article/f2af40acd84148669d6f31a51b5f7bd6
Autor:
Jennifer Huen, Zhun Yan, Jeremy Iwashkiw, Shraddha Dubey, Maria C. Gimenez, Maria E. Ortiz, Saumil V. Patel, Michael D. Jones, Ali Riazi, Mauricio Terebiznik, Saeid Babaei, Dea Shahinas
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The enteric pathogen, Salmonella enterica is a major cause of human gastroenteritis globally and with increasing bacterial resistance to antibiotics, alternative solutions are urgently needed. Single domain antibodies (sdAbs), the smallest antibody f
Externí odkaz:
https://doaj.org/article/0bef2dd788aa4b5e990405e1d6b53bc9
Publikováno v:
Structure. 25:469-481
Summary CshA is a dimeric DEAD-box helicase that cooperates with ribonucleases for mRNA turnover. The molecular mechanism for how a dimeric DEAD-box helicase aids in RNA decay remains unknown. Here, we report the crystal structure and small-angle X-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd076bce01ee329dc61d5bb584a8845
https://doi.org/10.1016/j.str.2017.01.012
https://doi.org/10.1016/j.str.2017.01.012
Publikováno v:
Biochemistry and Cell Biology. 88:77-88
The Rvb1 and Rvb2 proteins are 2 members of the AAA+ family, involved in roles as diverse as chromatin remodeling, transcription, small nucleolar RNA maturation, cellular transformation, signaling of apoptosis and mitosis. These proteins are capable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bfdd189cdb55a34017307868199f0d0
https://doi.org/10.1139/o09-159
https://doi.org/10.1139/o09-159
Autor:
Yoshito Kakihara, Francisca Ugwu, Jennifer Huen, Joaquin Ortega, Kevin Cheung, Walid A. Houry
Publikováno v:
Biochemistry and Cell Biology. 88:29-40
Rvb1 and Rvb2 are highly conserved, essential AAA+ helicases found in a wide range of eukaryotes. The versatility of these helicases and their central role in the biology of the cell is evident from their involvement in a wide array of critical cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d6be37e4dd4d22633db37fe509441d5
https://doi.org/10.1139/o09-122
https://doi.org/10.1139/o09-122
Autor:
Christopher M. Yip, Timothy P. Hughes, Jennifer Huen, Yoshito Kakihara, Rongmin Zhao, Anna Gribun, Renee L. Brost, May Khanna, Michael Costanzo, Guocheng Yang, Walid A. Houry, Charles Boone
Publikováno v:
The Journal of Cell Biology
Hsp90 is a highly conserved molecular chaperone that is involved in modulating a multitude of cellular processes. In this study, we identify a function for the chaperone in RNA processing and maintenance. This functionality of Hsp90 involves two rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bf0f5a927e2ce95131a7e31f99ca4e
https://doi.org/10.1083/jcb.200709061
https://doi.org/10.1083/jcb.200709061
Yeast rvb1 and rvb2 proteins oligomerize as a conformationally variable dodecamer with low frequency
Autor:
Liang Zhao, Nardin Nano, Jennifer Huen, Vivian Leong, Walid A. Houry, Joaquin Ortega, Ajitha Jeganathan
Publikováno v:
Journal of molecular biology. 427(10)
Rvb1 and Rvb2 are conserved AAA + (ATPases associated with diverse cellular activities) proteins found at the core of large multicomponent complexes that play key roles in chromatin remodeling, integrity of the telomeres, ribonucleoprotein complex bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbe9d87c4ab34cf6f97594a1ca95aea
https://pubmed.ncbi.nlm.nih.gov/25636407
https://pubmed.ncbi.nlm.nih.gov/25636407
Rvb1 and Rvb2 are essential AAA(+) (ATPases associated with diverse cellular activities) helicases, which are important components of critical complexes such as chromatin remodeling and telomerase complexes. The oligomeric state of the Rvb proteins h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bb35d2bda53b72b7a350bf3fb53eff
https://europepmc.org/articles/PMC2982833/
https://europepmc.org/articles/PMC2982833/
Autor:
Jennifer, Huen, Yoshito, Kakihara, Francisca, Ugwu, Kevin L Y, Cheung, Joaquin, Ortega, Walid A, Houry
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 88(1)
Rvb1 and Rvb2 are highly conserved, essential AAA+ helicases found in a wide range of eukaryotes. The versatility of these helicases and their central role in the biology of the cell is evident from their involvement in a wide array of critical cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89b006fe802ad1f5f6e9c0119f3dc4f6
https://pubmed.ncbi.nlm.nih.gov/20130677
https://pubmed.ncbi.nlm.nih.gov/20130677