Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jennifer Hesson"'
Autor:
Alec ST Smith, Shawn M Luttrell, Jean-Baptiste Dupont, Kevin Gray, Daniel Lih, Jacob W Fleming, Nathan J Cunningham, Sofia Jepson, Jennifer Hesson, Julie Mathieu, Lisa Maves, Bonnie J Berry, Elliot C Fisher, Nathan J Sniadecki, Nicholas A Geisse, David L Mack
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Engineered muscle tissues represent powerful tools for examining tissue level contractile properties of skeletal muscle. However, limitations in the throughput associated with standard analysis methods limit their utility for longitudinal study, high
Externí odkaz:
https://doaj.org/article/565ad4a21c544b2c9f25e7a2e203b886
Autor:
Alec S. T. Smith, Changho Chun, Jennifer Hesson, Julie Mathieu, Paul N. Valdmanis, David L. Mack, Byung-Ok Choi, Deok-Ho Kim, Mark Bothwell
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Gene editing technologies hold great potential to enhance our ability to model inheritable neurodegenerative diseases. Specifically, engineering multiple amyotrophic lateral sclerosis (ALS) mutations into isogenic cell populations facilitates determi
Externí odkaz:
https://doaj.org/article/b867e9f17fc7469794bf34151937519a
Autor:
Wendy Yang, Paul D. Lampe, Patricia Kensel-Hammes, Jennifer Hesson, Carol B. Ware, Laura Crisa, Vincenzo Cirulli
Publikováno v:
iScience, Vol 19, Iss , Pp 450-460 (2019)
Summary: Efficient stem cell differentiation into pancreatic islet cells is of critical importance for the development of cell replacement therapies for diabetes. Here, we identify the expression pattern of connexin 43 (Cx43), a gap junction (GJ) cha
Externí odkaz:
https://doaj.org/article/e031a3a500ff4f00a1541a18ae2cedc1
Autor:
Stephanie L. Battle, Naresh Doni Jayavelu, Robert N. Azad, Jennifer Hesson, Faria N. Ahmed, Eliah G. Overbey, Joseph A. Zoller, Julie Mathieu, Hannele Ruohola-Baker, Carol B. Ware, R. David Hawkins
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1129-1144 (2019)
Summary: During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (prime
Externí odkaz:
https://doaj.org/article/a4701e94f0d8402a95a19165a7d8c1db
Autor:
Hyeon-Jin Kim, Galip Gürkan Yardımcı, Giancarlo Bonora, Vijay Ramani, Jie Liu, Ruolan Qiu, Choli Lee, Jennifer Hesson, Carol B Ware, Jay Shendure, Zhijun Duan, William Stafford Noble
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 9, p e1008173 (2020)
Single-cell Hi-C (scHi-C) interrogates genome-wide chromatin interaction in individual cells, allowing us to gain insights into 3D genome organization. However, the extremely sparse nature of scHi-C data poses a significant barrier to analysis, limit
Externí odkaz:
https://doaj.org/article/d087140ff4c3496697afe98471225fab
Autor:
Alec S.T. Smith, Jong Hyun Kim, Changho Chun, Ava Gharai, Hyo Won Moon, Eun Young Kim, Soo Hyun Nam, Nina Ha, Ju Young Song, Ki Wha Chung, Hyun Myung Doo, Jennifer Hesson, Julie Mathieu, Mark Bothwell, Byung‐Ok Choi, Deok‐Ho Kim
Publikováno v:
Adv Biol (Weinh)
Charcot-Marie-Tooth disease type 2D (CMT2D), is a hereditary peripheral neuropathy caused by mutations in the gene encoding glycyl-tRNA synthetase (GARS1). Here, human induced pluripotent stem cell (hiPSC)-based models of CMT2D bearing mutations in G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3bb5b8a8e38b16446873b0a0ca4cba
https://europepmc.org/articles/PMC8849597/
https://europepmc.org/articles/PMC8849597/
Autor:
Naresh Doni Jayavelu, Eliah G. Overbey, R. David Hawkins, Hannele Ruohola-Baker, Julie Mathieu, Stephanie L. Battle, Robert N. Azad, Jennifer Hesson, Faria N. Ahmed, Carol B. Ware, Joseph A. Zoller
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1129-1144 (2019)
Summary: During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (prime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25191df476e612d246cb27c68ead68e4
https://doi.org/10.1016/j.stemcr.2019.04.004
https://doi.org/10.1016/j.stemcr.2019.04.004
Autor:
Alec S.T. Smith, Jong Hyun Kim, Changho Chun, Ava Gharai, Hyo Won Moon, Eun Young Kim, Soo Hyun Nam, Nina Ha, Ju Young Song, Ki Wha Chung, Hyun Myung Doo, Jennifer Hesson, Julie Mathieu, Mark Bothwell, Byung‐Ok Choi, Deok‐Ho Kim
Publikováno v:
Advanced Biology. 6:2270021
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df3313115afcf97959ac636fee763896
https://doi.org/10.1002/adbi.202270021
https://doi.org/10.1002/adbi.202270021
Autor:
Xinxian Deng, Carol B. Ware, Anton Krumm, Christine M. Disteche, Jay Shendure, Ferhat Ay, Choli Lee, Christopher Cavanaugh, Savannah Cook, Jennifer Hesson, Wenxiu Ma, Günhan Gülsoy, Zhijun Duan, C. Anthony Blau, William Stafford Noble
Publikováno v:
Methods. 142:59-73
The folding and three-dimensional (3D) organization of chromatin in the nucleus critically impacts genome function. The past decade has witnessed rapid advances in genomic tools for delineating 3D genome architecture. Among them, chromosome conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5027f50ddaad5c5b1c6718239f55a9
https://doi.org/10.1016/j.ymeth.2018.01.014
https://doi.org/10.1016/j.ymeth.2018.01.014
Autor:
Choli Lee, William Stafford Noble, Carol B. Ware, Ruolan Qiu, Giancarlo Bonora, Galip Gurkan Yardimici, Jennifer Hesson, Jay Shendure, Jie Liu, Zhijun Duan, Vijay Ramani, Hyeon-Jin Kim
Single-cell Hi-C (scHi-C) interrogates genome-wide chromatin interaction in individual cells, allowing us to gain insights into 3D genome organization. However, the extremely sparse nature of scHi-C data poses a significant barrier to analysis, limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db35f7e5ba2759d8e14b14da2d0a400