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pro vyhledávání: '"Jennifer Heidbrink-Thompson"'
Autor:
Srilatha Kuntumalla, Guijie Zhu, Hung Yu Lin, James B. McGivney, Christopher Larkin, Norman J. Dovichi, Jennifer Heidbrink-Thompson, Liangliang Sun
Publikováno v:
ELECTROPHORESIS. 37:616-622
We have evaluated CZE-ESI-MS/MS for detection of trace amounts of host cell protein impurities in recombinant therapeutics. Compared to previously published procedures, we have optimized the buffer pH used in the formation of a pH junction to increas