Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Jennifer H. Steel"'
Autor:
Ylenia Perone, Aaron J. Farrugia, Alba Rodríguez-Meira, Balázs Győrffy, Charlotte Ion, Andrea Uggetti, Antonios Chronopoulos, Pasquale Marrazzo, Monica Faronato, Sami Shousha, Claire Davies, Jennifer H. Steel, Naina Patel, Armando del Rio Hernandez, Charles Coombes, Giancarlo Pruneri, Adrian Lim, Fernando Calvo, Luca Magnani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
ERα breast cancer can relapse to metastatic disease following endocrine therapy. Here, the authors find that when aromatase inhibitor treatment resistance develops, epigenomic reprogramming drives Keratin-80 upregulation via SREBP1, and promotes cyt
Externí odkaz:
https://doaj.org/article/89df65835066448cbf1f8b48e72f3298
Autor:
Madhuri S. Salker, Jennifer H. Steel, Zohreh Hosseinzadeh, Jaya Nautiyal, Zoe Webster, Yogesh Singh, Sara Brucker, Florian Lang, Jan J. Brosens
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 5, Pp 2077-2087 (2016)
Background: Serum & Glucocorticoid Regulated Kinase 1 (SGK1) plays a fundamental role in ion and solute transport processes in epithelia. In the endometrium, down-regulation of SGK1 during the window of receptivity facilitates embryo implantation whe
Externí odkaz:
https://doaj.org/article/ba2118b95081494d88db684b0225b511
Autor:
Van T. M. Nguyen, Iros Barozzi, Monica Faronato, Ylenia Lombardo, Jennifer H. Steel, Naina Patel, Philippa Darbre, Leandro Castellano, Balázs Győrffy, Laura Woodley, Alba Rodriguez-Meira, Darren K. Patten, Valentina Vircillo, Manikandan Periyasamy, Simak Ali, Gianmaria Frige, Saverio Minucci, R. Charles Coombes, Luca Magnani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/69915c68314f4c4da72a9fec0920fcd9
Autor:
Ylenia Perone, Aaron J. Farrugia, Alba Rodríguez-Meira, Balázs Győrffy, Charlotte Ion, Andrea Uggetti, Antonios Chronopoulos, Pasquale Marrazzo, Monica Faronato, Sami Shousha, Claire Davies, Jennifer H. Steel, Naina Patel, Armando del Rio Hernandez, Charles Coombes, Giancarlo Pruneri, Adrian Lim, Fernando Calvo, Luca Magnani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/fff95096dfe94029b18485fd44cda673
Autor:
Robert Brown, Jerry S. Lanchbury, Hani Gabra, Nadeem Siddiqui, Liz-Anne Lewsley, Xinxue Liu, Jennifer H. Steel, Mona El-Bahrawy, Alexander Gutin, Michael Perry, Christopher Neff, Krystal Brown, Elisha Hughes, Kirsten M. Timms, James Paul, Euan A. Stronach
The current study evaluated three biomarkers [homologous recombination deficiency (HRD), tumor BRCA1/2 (tBRCA) mutations, and CCNE1 copy-number variation (CNV)] in ovarian tumors from patients enrolled on the SCOTROC4 clinical trial for associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::403af0f1740cae947c1b7ba5bb996251
https://doi.org/10.1158/1541-7786.c.6541371
https://doi.org/10.1158/1541-7786.c.6541371
Autor:
Robert Brown, Jerry S. Lanchbury, Hani Gabra, Nadeem Siddiqui, Liz-Anne Lewsley, Xinxue Liu, Jennifer H. Steel, Mona El-Bahrawy, Alexander Gutin, Michael Perry, Christopher Neff, Krystal Brown, Elisha Hughes, Kirsten M. Timms, James Paul, Euan A. Stronach
Supplemental Figure 1. Flow of patients and samples through study Supplemental Figure 2. Receiver operating curve (ROC) for HRD as a predictor of CA125 response in the HGSOC subset. Supplementary Table 1. Clinical characteristics and patient outcome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100565dfec09b57a158da7e8e3c81c80
https://doi.org/10.1158/1541-7786.22516485.v1
https://doi.org/10.1158/1541-7786.22516485.v1
Autor:
Simak Ali, R. Charles Coombes, Ian O. Ellis, Emad A. Rakha, Laki Buluwela, Sami Shousha, Frances Fuller-Pace, Louise J. Jones, Balázs Győrffy, Luca Magnani, Jennifer J. Gomm, Sally Smith, Judit Remenyi, Dena Jerjees, Claudia Busonero, Naina Patel, Jennifer H. Steel, Carolina Gemma, Alison Harrod, Manikandan Periyasamy, Chun-Fui Lai, Rezvan Abduljabbar, Hetal Patel
Supplementary Table 1. Multivariate Cox Regression Analysis for Time to Distant Metastasis (TTDM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de403ba18d48c3e7e197a85a45eed3a
https://doi.org/10.1158/1078-0432.22458171.v1
https://doi.org/10.1158/1078-0432.22458171.v1
Autor:
Simak Ali, R. Charles Coombes, Ian O. Ellis, Emad A. Rakha, Laki Buluwela, Sami Shousha, Frances Fuller-Pace, Louise J. Jones, Balázs Győrffy, Luca Magnani, Jennifer J. Gomm, Sally Smith, Judit Remenyi, Dena Jerjees, Claudia Busonero, Naina Patel, Jennifer H. Steel, Carolina Gemma, Alison Harrod, Manikandan Periyasamy, Chun-Fui Lai, Rezvan Abduljabbar, Hetal Patel
Supplementary Figure 1. Expression of CDK7, cyclin H and MAT1 is elevated in breast cancer. Supplementary Figure 2. Relationship between mRNA levels of CDK7, cyclin H and MAT1 in breast cancer. Supplementary Figure 3. Profiling of CDK7, Cyclin H and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022b0dc1d4bc3716a7cb72ef996390db
https://doi.org/10.1158/1078-0432.22458174.v1
https://doi.org/10.1158/1078-0432.22458174.v1
Autor:
Simak Ali, R. Charles Coombes, Ian O. Ellis, Emad A. Rakha, Laki Buluwela, Sami Shousha, Frances Fuller-Pace, Louise J. Jones, Balázs Győrffy, Luca Magnani, Jennifer J. Gomm, Sally Smith, Judit Remenyi, Dena Jerjees, Claudia Busonero, Naina Patel, Jennifer H. Steel, Carolina Gemma, Alison Harrod, Manikandan Periyasamy, Chun-Fui Lai, Rezvan Abduljabbar, Hetal Patel
Purpose: CDK-activating kinase (CAK) is required for the regulation of the cell cycle and is a trimeric complex consisting of cyclin-dependent kinase 7 (CDK7), Cyclin H, and the accessory protein, MAT1. CDK7 also plays a critical role in regulating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa678e7db7bda605727ecce058e9bd1
https://doi.org/10.1158/1078-0432.c.6523854.v1
https://doi.org/10.1158/1078-0432.c.6523854.v1
Autor:
Wilbert Zwart, Malcolm G. Parker, Jason S. Carroll, Lodewyk F.A. Wessels, Jennifer H. Steel, Ariel Poliandri, Jaya Nautiyal, Suzan Stelloo, Ekaterina Nevedomskaya, Meritxell Rosell
Supplementary Figure S2. Exogenous overexpression of RIP140 does not affect RIP140 chromatin interactions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17969c43fd4f0a3b9061c86d7795e79e
https://doi.org/10.1158/0008-5472.22404581.v1
https://doi.org/10.1158/0008-5472.22404581.v1