Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jennifer H Jonason"'
Autor:
Rubens Sautchuk, Brianna H Kalicharan, Katherine Escalera-Rivera, Jennifer H Jonason, George A Porter, Hani A Awad, Roman A Eliseev
Publikováno v:
eLife, Vol 11 (2022)
Cyclophilin D (CypD) promotes opening of the mitochondrial permeability transition pore (MPTP) which plays a key role in both cell physiology and pathology. It is, therefore, beneficial for cells to tightly regulate CypD and MPTP but little is known
Externí odkaz:
https://doaj.org/article/31fd707cae064039a605cbafca3401bd
Autor:
Qurratul-Ain Dar, Eric M Schott, Sarah E Catheline, Robert D Maynard, Zhaoyang Liu, Fadia Kamal, Christopher W Farnsworth, John P Ketz, Robert A Mooney, Matthew J Hilton, Jennifer H Jonason, Janne Prawitt, Michael J Zuscik
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174705 (2017)
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease modifying therapies. Thus, strategies that offer chondroprotective or regenerative capability represent a critical unmet need. Recently, oral consumption of a hydrolyz
Externí odkaz:
https://doaj.org/article/ec104c274e734809af1fa423b08845bc
Autor:
Laura C Shum, Noelle S White, Sergiy M Nadtochiy, Karen L de Mesy Bentley, Paul S Brookes, Jennifer H Jonason, Roman A Eliseev
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155709 (2016)
Pathogenic factors associated with aging, such as oxidative stress and hormone depletion converge on mitochondria and impair their function via opening of the mitochondrial permeability transition pore (MPTP). The MPTP is a large non-selective pore r
Externí odkaz:
https://doaj.org/article/8cf59e506817440ebb6201ddb3ce1570
Autor:
Emmanuela Adjei-Sowah, Yue Peng, Jason Weeks, Jennifer H. Jonason, Karen L. de Mesy Bentley, Elysia Masters, Yugo Morita, Gowrishankar Muthukrishnan, Philip Cherian, X. Eric Hu, Charles E. McKenna, Frank H. Ebetino, Shuting Sun, Edward M. Schwarz, Chao Xie
Publikováno v:
Antibiotics, Vol 10, Iss 6, p 732 (2021)
The use of local antibiotics to treat bone infections has been questioned due to a lack of clinical efficacy and emerging information about Staphylococcus aureus colonization of the osteocyte-lacuno canalicular network (OLCN). Here we propose bisphos
Externí odkaz:
https://doaj.org/article/55d8be3a8e344453a7cad2e4bff9c98b
Autor:
Xi Lin, Richard D. Bell, Sarah E. Catheline, Takahiro Takano, Andrew McDavid, Jennifer H. Jonason, Edward M. Schwarz, Lianping Xing
Publikováno v:
Arthritis & Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f5bcaf26a2841e18ad0eb6fceece94a
https://doi.org/10.1002/art.42441
https://doi.org/10.1002/art.42441
Autor:
Benjamin D. Kuhns, John M. Reuter, Victoria L. Hansen, Gillian L. Soles, Jennifer H. Jonason, Cheryl L. Ackert‐Bicknell, Chia‐Lung Wu, Brian D. Giordano
Publikováno v:
J Orthop Res
Femoroacetabular impingement (FAI) has a strong clinical association with the development of hip osteoarthritis (OA); however, the pathobiological mechanisms underlying the transition from focal impingement to global joint degeneration remain poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbc2ac1e2d8ca3ea1e8f80a85958113
https://pubmed.ncbi.nlm.nih.gov/36463522
https://pubmed.ncbi.nlm.nih.gov/36463522
Autor:
Jennifer H. Jonason, Hani A. Awad, Escalera-Rivera K, George A. Porter, Roman A. Eliseev, Rubens Sautchuk, Kalicharan Bh
Publikováno v:
eLife. 11
SUMMARYCyclophilin D (CypD) promotes opening of the mitochondrial permeability transition pore (MPTP) which plays a key role in both cell physiology and pathology. It is, therefore beneficial for cells to tightly regulate CypD and MPTP but little is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba30481ab4ae221d3ad05a90f2458d18
https://doi.org/10.7554/elife.75023
https://doi.org/10.7554/elife.75023
Autor:
Benjamin D. Kuhns, John M. Reuter, Victoria L. Hansen, Gillian Soles, Jennifer H. Jonason, Cheryl Ackert-Bicknell, Chia-Lung Wu, Brian D. Giordano
IntroductionThe natural history of Femoroacetabular Impingement (FAI) has been clinically associated with the development of hip osteoarthritis (OA); however, the pathobiological mechanisms underlying the transition from focal impingement to global j
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b4919a614044682217e90c2b1b86cd
https://doi.org/10.1101/2022.05.23.492951
https://doi.org/10.1101/2022.05.23.492951
Autor:
Christopher Dean, Brendan F. Boyce, M. Nick James, Martin Chang, Michael J. Zuscik, John P. Ketz, Elizabeth Botto, Katherine Escalera-Rivera, Richard D. Bell, Luke S. Oluoch, Sarah E. Catheline, Jennifer H. Jonason, Robert D. Maynard
Publikováno v:
Science signaling. 14(701)
Canonical nuclear factor κB (NF-κB) signaling mediated by homo- and heterodimers of the NF-κB subunits p65 (RELA) and p50 (NFKB1) is associated with age-related pathologies and with disease progression in posttraumatic models of osteoarthritis (OA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bf996e28e6e2081c7203bacbe63c37
https://pubmed.ncbi.nlm.nih.gov/35380880
https://pubmed.ncbi.nlm.nih.gov/35380880