Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Jennifer H Jonason"'
Autor:
Rubens Sautchuk, Brianna H Kalicharan, Katherine Escalera-Rivera, Jennifer H Jonason, George A Porter, Hani A Awad, Roman A Eliseev
Publikováno v:
eLife, Vol 11 (2022)
Cyclophilin D (CypD) promotes opening of the mitochondrial permeability transition pore (MPTP) which plays a key role in both cell physiology and pathology. It is, therefore, beneficial for cells to tightly regulate CypD and MPTP but little is known
Externí odkaz:
https://doaj.org/article/31fd707cae064039a605cbafca3401bd
Autor:
Xi Lin, Richard D. Bell, Sarah E. Catheline, Takahiro Takano, Andrew McDavid, Jennifer H. Jonason, Edward M. Schwarz, Lianping Xing
Publikováno v:
Arthritis & Rheumatology.
Autor:
Emmanuela Adjei-Sowah, Yue Peng, Jason Weeks, Jennifer H. Jonason, Karen L. de Mesy Bentley, Elysia Masters, Yugo Morita, Gowrishankar Muthukrishnan, Philip Cherian, X. Eric Hu, Charles E. McKenna, Frank H. Ebetino, Shuting Sun, Edward M. Schwarz, Chao Xie
Publikováno v:
Antibiotics, Vol 10, Iss 6, p 732 (2021)
The use of local antibiotics to treat bone infections has been questioned due to a lack of clinical efficacy and emerging information about Staphylococcus aureus colonization of the osteocyte-lacuno canalicular network (OLCN). Here we propose bisphos
Externí odkaz:
https://doaj.org/article/55d8be3a8e344453a7cad2e4bff9c98b
Autor:
Qurratul-Ain Dar, Eric M Schott, Sarah E Catheline, Robert D Maynard, Zhaoyang Liu, Fadia Kamal, Christopher W Farnsworth, John P Ketz, Robert A Mooney, Matthew J Hilton, Jennifer H Jonason, Janne Prawitt, Michael J Zuscik
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174705 (2017)
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease modifying therapies. Thus, strategies that offer chondroprotective or regenerative capability represent a critical unmet need. Recently, oral consumption of a hydrolyz
Externí odkaz:
https://doaj.org/article/ec104c274e734809af1fa423b08845bc
Autor:
Benjamin D. Kuhns, John M. Reuter, Victoria L. Hansen, Gillian L. Soles, Jennifer H. Jonason, Cheryl L. Ackert‐Bicknell, Chia‐Lung Wu, Brian D. Giordano
Publikováno v:
J Orthop Res
Femoroacetabular impingement (FAI) has a strong clinical association with the development of hip osteoarthritis (OA); however, the pathobiological mechanisms underlying the transition from focal impingement to global joint degeneration remain poorly
Autor:
Jennifer H. Jonason, Hani A. Awad, Escalera-Rivera K, George A. Porter, Roman A. Eliseev, Rubens Sautchuk, Kalicharan Bh
Publikováno v:
eLife. 11
SUMMARYCyclophilin D (CypD) promotes opening of the mitochondrial permeability transition pore (MPTP) which plays a key role in both cell physiology and pathology. It is, therefore beneficial for cells to tightly regulate CypD and MPTP but little is
Autor:
Benjamin D. Kuhns, John M. Reuter, Victoria L. Hansen, Gillian Soles, Jennifer H. Jonason, Cheryl Ackert-Bicknell, Chia-Lung Wu, Brian D. Giordano
IntroductionThe natural history of Femoroacetabular Impingement (FAI) has been clinically associated with the development of hip osteoarthritis (OA); however, the pathobiological mechanisms underlying the transition from focal impingement to global j
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b4919a614044682217e90c2b1b86cd
https://doi.org/10.1101/2022.05.23.492951
https://doi.org/10.1101/2022.05.23.492951
Autor:
Laura C Shum, Noelle S White, Sergiy M Nadtochiy, Karen L de Mesy Bentley, Paul S Brookes, Jennifer H Jonason, Roman A Eliseev
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155709 (2016)
Pathogenic factors associated with aging, such as oxidative stress and hormone depletion converge on mitochondria and impair their function via opening of the mitochondrial permeability transition pore (MPTP). The MPTP is a large non-selective pore r
Externí odkaz:
https://doaj.org/article/8cf59e506817440ebb6201ddb3ce1570
Autor:
Christopher Dean, Brendan F. Boyce, M. Nick James, Martin Chang, Michael J. Zuscik, John P. Ketz, Elizabeth Botto, Katherine Escalera-Rivera, Richard D. Bell, Luke S. Oluoch, Sarah E. Catheline, Jennifer H. Jonason, Robert D. Maynard
Publikováno v:
Science signaling. 14(701)
Canonical nuclear factor κB (NF-κB) signaling mediated by homo- and heterodimers of the NF-κB subunits p65 (RELA) and p50 (NFKB1) is associated with age-related pathologies and with disease progression in posttraumatic models of osteoarthritis (OA