Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jennifer H, Law"'
Autor:
Shelley Kuang, Kaitlin Chen, Sachin Sayal, Gajeni Prabahan, Mary R. Rabey, Lisa W. Le, Andrew Seto, Frances A. Shepherd, Geoffrey Liu, Penelope Bradbury, Adrian G. Sacher, Jennifer H. Law, Peter Sabatini, Tracy L. Stockley, Ming S. Tsao, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4476-4485 (2024)
In advanced non-squamous non-small-cell lung cancer (NSCLC), routine testing with next-generation sequencing (NGS) is recommended to identify actionable genomic alterations (AGAs). The therapeutic implications of repeated NGS testing on synchronous a
Externí odkaz:
https://doaj.org/article/b1046990507e43358bd21c8d115538a3
Autor:
Shelley Kuang, Andrea S. Fung, Kirstin A. Perdrizet, Kaitlin Chen, Janice J. N. Li, Lisa W. Le, Michael Cabanero, Ola Abu Al Karsaneh, Ming S. Tsao, Josh Morganstein, Laura Ranich, Adam C. Smith, Cuihong Wei, Carol Cheung, Frances A. Shepherd, Geoffrey Liu, Penelope Bradbury, Prodipto Pal, Joerg Schwock, Adrian G. Sacher, Jennifer H. Law, Tracy L. Stockley, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 4428-4437 (2022)
In advanced non-small cell lung cancer (NSCLC), patients with actionable genomic alterations may derive additional clinical benefit from targeted treatment compared to cytotoxic chemotherapy. Current guidelines recommend extensive testing with next g
Externí odkaz:
https://doaj.org/article/1eeb191a55df4e19870dc32a209c27eb
Autor:
Maisam Makarem, Doreen A. Ezeife, Adam C. Smith, Janice J. N. Li, Jennifer H. Law, Ming-Sound Tsao, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3268-3279 (2021)
ROS1 rearrangements are identified in 1–2% of lung adenocarcinoma cases, and reflex testing is guideline-recommended. We developed a decision model for population-based ROS1 testing from a Canadian public healthcare perspective to determine the str
Externí odkaz:
https://doaj.org/article/e93481a624f5442e94ebd6f4eb8c6fbc
Autor:
Miguel Garcia-Pardo, Kasia Czarnecka, Jennifer H. Law, Alexandra Salvarrey, Roxanne Fernandes, Jason Fan, Lucy Corke, Thomas K. Waddell, Kazuhiro Yasufuku, Laura L. Donahoe, Andrew Pierre, Lisa W. Le, Noor Ghumman, Geoffrey Liu, Frances A. Shepherd, Penelope Bradbury, Adrian Sacher, Tracy Stockley, Prodipto Pal, Patrik Rogalla, Ming Sound Tsao, Natasha B. Leighl
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Introduction: Molecular profiling of tumor tissue is the gold standard for treatment decision-making in advanced non-small cell lung cancer (NSCLC). Results may be delayed or unavailable due to insufficient tissue, prolonged wait times for biopsy, pa
Externí odkaz:
https://doaj.org/article/6d16f75f675e4c909e12ca7dabb73091
Autor:
Doreen A. Ezeife, Eldon Spackman, Rosalyn A. Juergens, Janessa J. Laskin, Jason S. Agulnik, Desiree Hao, Scott A. Laurie, Jennifer H. Law, Lisa W. Le, Lesli A. Kiedrowski, Barbara Melosky, Frances A. Shepherd, Victor Cohen, Paul Wheatley-Price, Rachel Vandermeer, Janice J. Li, Roxanne Fernandes, Aria Shokoohi, Richard B. Lanman, Natasha B. Leighl
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Liquid biopsy (LB) can detect actionable genomic alterations in plasma circulating tumor circulating tumor DNA beyond tissue testing (TT) alone in advanced non-small cell lung cancer (NSCLC) patients. We estimated the cost-effectiveness o
Externí odkaz:
https://doaj.org/article/a8d487bdfc16404a9f1aade6c7be2b14
Autor:
Marie-Pier Gauthier, MD, Jennifer H. Law, MSc, Lisa W. Le, MSc, Janice J.N. Li, BSc, Sajda Zahir, Sharon Nirmalakumar, BSc, Mike Sung, MD, Christopher Pettengell, BMBCh, Steven Aviv, BBusSc, Ryan Chu, MD, Adrian Sacher, MD, MSc, Geoffrey Liu, MD, MSc, Penelope Bradbury, MBChB, Frances A. Shepherd, MD, Natasha B. Leighl, MD, MMSc, FRCPC, FASCO
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 6, Pp 100340- (2022)
Introduction: Real-world evidence is important in regulatory and funding decisions. Manual data extraction from electronic health records (EHRs) is time-consuming and challenging to maintain. Automated extraction using natural language processing (NL
Externí odkaz:
https://doaj.org/article/2e86472fb96d485497868949b557bcaa
Autor:
Kirstin Perdrizet, Tracy L. Stockley, Jennifer H. Law, Adam Smith, Tong Zhang, Roxanne Fernandes, Muqdas Shabir, Peter Sabatini, Nadia Al Youssef, Christine Ishu, Janice JN Li, Ming-Sound Tsao, Prodipto Pal, Michael Cabanero, Joerg Schwock, Hyang Mi Ko, Scott Boerner, Heather Ruff, Frances A. Shepherd, Penelope A. Bradbury, Geoffrey Liu, Adrian G. Sacher, Natasha B. Leighl
Publikováno v:
Cancer Treatment and Research Communications, Vol 31, Iss , Pp 100534- (2022)
Objectives: Standard molecular testing for patients with stage IV non-small cell lung cancer (NSCLC) in the Canadian publicly funded health system includes single gene testing for EGFR, ALK, and ROS-1. Comprehensive genomic profiling (CGP) may broade
Externí odkaz:
https://doaj.org/article/efa5907711174a89a85365493ff18f7d
Autor:
Sandra E. Dunn, Michael Pollak, Marco Gottardis, Joan Carboni, Robert I. Nicholson, Helen E. Jones, Pauline Finlay, Julia M.W. Gee, Eugene Park, Anna L. Stratford, Michelle Y.C. Wang, Hamid Masoudi, Kaiji Hu, Golareh Habibi, Jennifer H. Law
Supplementary Figure 1 from Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed96153bfbcc226a63b1ca283392dc9
https://doi.org/10.1158/0008-5472.22375809.v1
https://doi.org/10.1158/0008-5472.22375809.v1
Autor:
Sandra E. Dunn, Connie J. Eaves, Hans-Dieter Royer, Isabelle M. Berquin, Pauline Johnson, Afshin Raouf, Anna L. Stratford, Lawrence Lee, Alastair H. Davies, Arezoo Astanehe, Jing Wang, Kaiji Hu, Jennifer H. Law, Kristen M. Reipas, Abbas Fotovati, Karen To
Supplementary Methods and Materials, Figures 1-6 from Y-Box Binding Protein-1 Induces the Expression of CD44 and CD49f Leading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d82df214052211b4407e274eea205de
https://doi.org/10.1158/0008-5472.22386402.v1
https://doi.org/10.1158/0008-5472.22386402.v1
Autor:
Doreen A, Ezeife, Brendon Josh, Morganstein, Steven, Yip, Malcolm, Ryan, Jennifer H, Law, Amy Yimin, Guan, Lisa W, Le, Aaron R, Hansen, Adrian, Sacher, Georg A, Bjarnason, Mark K, Doherty, Natasha B, Leighl
Publikováno v:
The Canadian journal of urology. 28(4)
INTRODUCTION Advances in novel treatment options may render renal cell cancer (RCC) patients susceptible to the financial toxicity (FT) of cancer treatment, and the factors associated with FT are unknown.Eligible patients were ≥ 18 years old and ha