Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jennifer Guerrero-Santoro"'
Autor:
Jennifer Guerrero-Santoro, Mayumi Morizane, Soo-Young Oh, Takuya Mishima, Julie P. Goff, Ibrahim Bildirici, Elena Sadovsky, Yingshi Ouyang, Vladimir A. Tyurin, Yulia Y. Tyurina, Valerian E. Kagan, Yoel Sadovsky
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
In eutherians, the placenta plays a critical role in the uptake, storage, and metabolism of lipids. These processes govern the availability of fatty acids to the developing fetus, where inadequate supply has been associated with substandard fetal gro
Externí odkaz:
https://doaj.org/article/aa167c14acbf47b98262778579432549
Multinucleated cells, or syncytia, are found in diverse taxa. Their biological function is often associated with the compartmentalization of biochemical or cellular activities within the syncytium. How such compartments are generated and maintained i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d4b673917da591100c79ee368640a58
https://doi.org/10.1101/2023.03.22.533866
https://doi.org/10.1101/2023.03.22.533866
Publikováno v:
Genome Research. 31:1680-1692
We used capped analysis of gene expression with sequencing (CAGE-seq) to profile eRNA expression and enhancer activity during embryogenesis of a model echinoderm: the sea urchin, Strongylocentrotus purpuratus. We identified more than 18,000 enhancers
Publikováno v:
Current topics in developmental biology. 146
The skeleton-forming cells of sea urchins and other echinoderms have been studied by developmental biologists as models of cell specification and morphogenesis for many decades. The gene regulatory network (GRN) deployed in the embryonic skeletogenic
Publikováno v:
Current Topics in Developmental Biology ISBN: 9780128171875
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81a1b08091b2120bac7f1f3346d74a0
https://doi.org/10.1016/bs.ctdb.2021.10.005
https://doi.org/10.1016/bs.ctdb.2021.10.005
The gene regulatory network (GRN) that underlies echinoderm skeletogenesis is a prominent model of GRN architecture and evolution. KirrelL is an essential downstream effector gene in this network and encodes an Ig-superfamily protein required for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d68ca2706e4c704b968346f04cf9a4c8
https://doi.org/10.1101/2021.08.27.457814
https://doi.org/10.1101/2021.08.27.457814
Autor:
Tianjiao Chu, Yoel Sadovsky, Kazuhiro Kajiwara, Jennifer Guerrero-Santoro, Yulia Y. Tyurina, Vladimir A. Tyurin, Valerian E. Kagan, Ofer Beharier, W. Tony Parks, Julie P. Goff, Callen T. Wallace, Claudette M. St. Croix, Samuel Parry
Publikováno v:
Proc Natl Acad Sci U S A
The recently identified ferroptotic cell death is characterized by excessive accumulation of hydroperoxy-arachidonoyl (C20:4)- or adrenoyl (C22:4)- phosphatidylethanolamine (Hp-PE). The selenium-dependent glutathione peroxidase 4 (GPX4) inhibits ferr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4932975995faf98fe6d0da9241e843e
https://europepmc.org/articles/PMC7959495/
https://europepmc.org/articles/PMC7959495/
Autor:
Ayşe Haruka Açıkbaş, Jian Ming Khor, James B. Jaynes, Charles A. Ettensohn, Jennifer Guerrero-Santoro
Publikováno v:
The Journal of Biological Chemistry
Alx1, a homeodomain-containing transcription factor, is a highly conserved regulator of skeletogenesis in echinoderms. In sea urchins, Alx1 plays a central role in the differentiation of embryonic primary mesenchyme cells (PMCs) and positively regula
Publikováno v:
Development (Cambridge, England). 146(16)
Alx1 is a conserved regulator of skeletogenesis in echinoderms and evolutionary changes in Alx1 sequence and expression have played a pivotal role in modifying programs of skeletogenesis within the phylum. Alx1 regulates a large suite of effector gen
Autor:
Vesna Rapić-Otrin, Ching L. Hsieh, Jennifer Guerrero-Santoro, Ilya Gorbachinsky, Arthur S. Levine, Maria G. Kapetanaki
Publikováno v:
Cancer Research. 68:5014-5022
By removing UV-induced lesions from DNA, the nucleotide excision repair (NER) pathway preserves the integrity of the genome. The UV-damaged DNA-binding (UV-DDB) protein complex is involved in the recognition of chromatin-embedded UV-damaged DNA, whic