Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jennifer Grubb"'
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008217 (2019)
During meiosis, homologous recombination repairs programmed DNA double-stranded breaks. Meiotic recombination physically links the homologous chromosomes ("homologs"), creating the tension between them that is required for their segregation. The cent
Externí odkaz:
https://doaj.org/article/562efdb3c0c441b886dbc4176ead607a
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005653 (2015)
The Eukaryotic RecA-like proteins Rad51 and Dmc1 cooperate during meiosis to promote recombination between homologous chromosomes by repairing programmed DNA double strand breaks (DSBs). Previous studies showed that Rad51 and Dmc1 form partially over
Externí odkaz:
https://doaj.org/article/0e6fc9312a264577991005ca692d3372
Autor:
Jessica P Lao, Veronica Cloud, Chu-Chun Huang, Jennifer Grubb, Drew Thacker, Chih-Ying Lee, Michael E Dresser, Neil Hunter, Douglas K Bishop
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003978 (2013)
During meiosis, repair of programmed DNA double-strand breaks (DSBs) by recombination promotes pairing of homologous chromosomes and their connection by crossovers. Two DNA strand-exchange proteins, Rad51 and Dmc1, are required for meiotic recombinat
Externí odkaz:
https://doaj.org/article/b29a371e47bf4cf1b0e472e7d7642981
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008217 (2019)
PLoS Genetics
PLoS Genetics
During meiosis, homologous recombination repairs programmed DNA double-stranded breaks. Meiotic recombination physically links the homologous chromosomes (“homologs”), creating the tension between them that is required for their segregation. The
Autor:
Junya Li, Douglas K. Bishop, Daniil V. Gataulin, Jennifer Grubb, Parisha P. Shah, Jeffrey N. Carey
Publikováno v:
Nucleic Acids Research
The Escherichia coli RecA protein catalyzes the central step of homologous recombination using its homology search and strand exchange activity. RecA is a DNA-dependent ATPase, but its homology search and strand exchange activities are largely indepe
Publikováno v:
Science. 337:1222-1225
Relegated to Accessory Critical aspects of meiosis, the specialized cell division that makes haploid gametes and spores, evolved from those of the normal mitotic cell cycle. In mitosis, the RecA homolog Rad51 is required for the homology-mediated rep
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 11, Iss 12, p e1005653 (2015)
PLoS Genetics, Vol 11, Iss 12, p e1005653 (2015)
The Eukaryotic RecA-like proteins Rad51 and Dmc1 cooperate during meiosis to promote recombination between homologous chromosomes by repairing programmed DNA double strand breaks (DSBs). Previous studies showed that Rad51 and Dmc1 form partially over
Publikováno v:
Journal of visualized experiments : JoVE. (102)
The small size of nuclei of the budding yeast Saccharomyces cerevisiae limits the utility of light microscopy for analysis of the subnuclear distribution of chromatin-bound proteins. Surface spreading of yeast nuclei results in expansion of chromatin
Publikováno v:
Journal of Cell Science.
Formation of crossovers between homologous chromosomes during meiosis is positively regulated by the ZMM proteins (also known as SIC proteins). DNA damage checkpoint proteins also promote efficient formation of interhomolog crossovers. Here, we exami
Autor:
Ming-Hui Lee, Yuan-Chih Chang, Ting-Fang Wang, Chia-Seng Chang, Douglas K. Bishop, Eurie L. Hong, Jennifer Grubb
Publikováno v:
Journal of Biological Chemistry. 280:40980-40984
Dmc1 is specifically required for homologous recombination during meiosis. Here we report that the calcium ion enabled Dmc1 from budding yeast to form regular helical filaments on single-stranded DNA (ssDNA) and activate its strand assimilation activ