Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jennifer Griswold"'
Autor:
Jennifer Wilson, Kanwar Bhinder, Shailesh Male, Richard Dalyai, Jennifer Griswold, Nurose Karim, Vikram Bhinder
Publikováno v:
Stroke. 54
Introduction: IVH clearance of more than 80% with intraventricular fibrinolysis administered via a conventional external ventricular drain (EVD) is associated with improvements in outcomes; however, 80% IVH clearance is difficult to achieve. The IRRA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c49e81b8716b6e7aedd19488897dd25
https://doi.org/10.1161/str.54.suppl_1.tp124
https://doi.org/10.1161/str.54.suppl_1.tp124
Autor:
Chinaza Egbuta, Gianfranco Gilardi, Jessica Lo, Debashis Ghosh, Giovanna Di Nardo, Wenhua Jiang, Jennifer Griswold
Publikováno v:
Biochemistry. 52:5821-5829
Cytochrome P450 aromatase (CYP19A1) is the only enzyme known to catalyze the biosynthesis of estrogens from androgens. The crystal structure of human placental aromatase (pArom) has paved the way toward understanding the structure-function relationsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4746d2adb6759f51509ed096be8486
https://doi.org/10.1021/bi400669h
https://doi.org/10.1021/bi400669h
Autor:
Chinaza Egbuta, Jessica Lo, Susan Hubbell, Jingle Xi, Debashis Ghosh, Daniel Morton, Damien Valette, Jennifer Griswold, Huw M. L. Davies, Jing An, Wenhua Jiang
Publikováno v:
Journal of Medicinal Chemistry. 55:8464-8476
Human cytochrome P450 aromatase catalyzes with high specificity the synthesis of estrogens from androgens. Aromatase inhibitors (AIs) such as exemestane, 6-methylideneandrosta-1,4-diene-3,17-dione, are preeminent drugs for the treatment of estrogen-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b59ff685777f71791738c21905aa535
https://doi.org/10.1021/jm300930n
https://doi.org/10.1021/jm300930n
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 118:197-202
Aromatase is a unique cytochrome P450 that catalyzes the removal of the 19-methyl group and aromatization of the A-ring of androgens for the synthesis of estrogens. All human estrogens are synthesized via this enzymatic aromatization pathway. Aromata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bc16e464984117f0d0730c47475f00
https://doi.org/10.1016/j.jsbmb.2009.09.012
https://doi.org/10.1016/j.jsbmb.2009.09.012
Publikováno v:
Nature. 457:219-223
Aromatase cytochrome P450 is the only enzyme in vertebrates known to catalyse the biosynthesis of all oestrogens from androgens. Aromatase inhibitors therefore constitute a frontline therapy for oestrogen-dependent breast cancer. In a three-step proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3a85b92cbeac120822d48015b5c7fe
https://doi.org/10.1038/nature07614
https://doi.org/10.1038/nature07614
Publikováno v:
Phytochemistry. 47:659-664
The amounts of two phenolic compounds, E-feruloyltyramine and E-p-coumaroyltyramine, increased 10-fold in tomato leaves in response to mechanical wounding, and 25-fold in response to the oligosaccharide elicitor chitosan. Using fluorescence detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017630bdba1da4a43bf78025274235ca
https://doi.org/10.1016/s0031-9422(97)00620-1
https://doi.org/10.1016/s0031-9422(97)00620-1
Autor:
Mary Erman, Yoshio Osawa, Tadayoshi Higashiyama, Debashis Ghosh, Traci Wagner, Jennifer Griswold, Puloma Lala
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 88(3)
Human cytochrome P450 aromatase (P450arom) is responsible for biosynthesis of estrogens from androgens. Monoclonal antibody MAb3-2C2 to P450arom specifically binds to a conformational epitope and suppresses the enzyme activity in a dose-dependent man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41dc6165a9bb20659e15fe0834e44387
https://pubmed.ncbi.nlm.nih.gov/15120417
https://pubmed.ncbi.nlm.nih.gov/15120417