Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jennifer Govero"'
Autor:
Jesse H. Erasmus, Jacob Archer, Jasmine Fuerte-Stone, Amit P. Khandhar, Emily Voigt, Brian Granger, Robin G. Bombardi, Jennifer Govero, Qing Tan, Lorellin A. Durnell, Rhea N. Coler, Michael S. Diamond, James E. Crowe, Jr., Steven G. Reed, Larissa B. Thackray, Robert H. Carnahan, Neal Van Hoeven
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 402-414 (2020)
Monoclonal antibody (mAb) therapeutics are an effective modality for the treatment of infectious, autoimmune, and cancer-related diseases. However, the discovery, development, and manufacturing processes are complex, resource-consuming activities tha
Externí odkaz:
https://doaj.org/article/caf03de341314d739fa7688cad7cbd42
Autor:
Sharmila Nair, Luciano Mazzoccoli, Arijita Jash, Jennifer Govero, Sachendra S. Bais, Tong Hu, Camila R. Fontes-Garfias, Chao Shan, Hideho Okada, Sujan Shresta, Jeremy N. Rich, Pei-Yong Shi, Michael S. Diamond, Milan G. Chheda
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Glioblastoma multiforme (GBM) is a fatal human cancer in part because GBM stem cells are resistant to therapy and recurrence is inevitable. Previously, we demonstrated Zika virus (ZIKV) targets GBM stem cells and prevents death of mice with gliomas.
Externí odkaz:
https://doaj.org/article/cc0774b684754a278d9b7e4db97ef179
Autor:
Jonathan J. Miner, Abdoulaye Sene, Justin M. Richner, Amber M. Smith, Andrea Santeford, Norimitsu Ban, James Weger-Lucarelli, Francesca Manzella, Claudia Rückert, Jennifer Govero, Kevin K. Noguchi, Gregory D. Ebel, Michael S. Diamond, Rajendra S. Apte
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3208-3218 (2016)
Zika virus (ZIKV) is an emerging flavivirus that causes congenital abnormalities and Guillain-Barré syndrome. ZIKV infection also results in severe eye disease characterized by optic neuritis, chorioretinal atrophy, and blindness in newborns and con
Externí odkaz:
https://doaj.org/article/766a998ca629426fbdb33df443eb65d9
Autor:
Estefania Fernandez, Nurgun Kose, Melissa A. Edeling, Jagat Adhikari, Gopal Sapparapu, Susana M. Lazarte, Christopher A. Nelson, Jennifer Govero, Michael L. Gross, Daved H. Fremont, James E. Crowe, Michael S. Diamond
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Japanese encephalitis virus (JEV) remains a leading cause of viral encephalitis worldwide. Although JEV-specific antibodies have been described, an assessment of their ability to neutralize multiple genotypes of JEV has been limited. Here, w
Externí odkaz:
https://doaj.org/article/e0e9979eba88468bb560f441c156690d
Autor:
Justin M Richner, Grzegorz B Gmyrek, Jennifer Govero, Yizheng Tu, Gerritje J W van der Windt, Talibah U Metcalf, Elias K Haddad, Johannes Textor, Mark J Miller, Michael S Diamond
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005027 (2015)
Impaired immune responses in the elderly lead to reduced vaccine efficacy and increased susceptibility to viral infections. Although several groups have documented age-dependent defects in adaptive immune priming, the deficits that occur prior to ant
Externí odkaz:
https://doaj.org/article/428524cb79c347d19ba0027797139d4d
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30184 (2012)
Numerous studies using cultured mammalian cells have shown that the three GGAs (Golgi-localized, gamma-ear containing, ADP-ribosylation factor- binding proteins) function in the transport of cargo proteins between the trans- Golgi network and endosom
Externí odkaz:
https://doaj.org/article/8b7cec6590c84d559fa51f27c2b71476
Autor:
Kimberly A. Dowd, Devika Sirohi, Scott D. Speer, Laura A. VanBlargan, Rita E. Chen, Swati Mukherjee, Bradley M. Whitener, Jennifer Govero, Maya Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S. Miller, Thomas Klose, Aihua Zheng, Scott Koenig, Margaret Kielian, Richard J. Kuhn, Michael S. Diamond, Theodore C. Pierson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Cleavage of the flavivirus premembrane (prM) structural protein during maturation can be inefficient. The contribution of partially mature flavivirus virions that retain uncleaved prM to pathogenesis during primary infection is unknown. To investigat
Autor:
Robin G. Bombardi, James E. Crowe, Jacob Archer, Steven G. Reed, Jennifer Govero, Jasmine Fuerte-Stone, Lorellin A. Durnell, Emily A. Voigt, Larissa B. Thackray, Brian Granger, Neal Van Hoeven, Qing Tan, Robert H. Carnahan, Rhea N. Coler, Jesse H. Erasmus, Amit P. Khandhar, Michael S. Diamond
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 402-414 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 402-414 (2020)
Monoclonal antibody (mAb) therapeutics are an effective modality for the treatment of infectious, autoimmune, and cancer-related diseases. However, the discovery, development, and manufacturing processes are complex, resource-consuming activities tha
Autor:
Subhajit Poddar, Elizabeth A. Caine, Jacques Halabi, Vanessa Salazar, Suzanne M. Scheaffer, Jennifer Govero, Kelle H. Moley, Darcy E. Broughton, Malgorzata E. Skaznik-Wikiel, Michael S. Diamond, Augustine Osula
Publikováno v:
J Infect Dis
Background Zika virus (ZIKV) has become a global concern because infection of pregnant mothers was linked to congenital birth defects. Zika virus is unique from other flaviviruses, because it is transmitted vertically and sexually in addition to by m
Autor:
Tong Hu, Luciano Mazzoccoli, Jeremy N. Rich, Sachendra S. Bais, Michael S. Diamond, Milan G. Chheda, Hideho Okada, Pei Yong Shi, Arijita Jash, Jennifer Govero, Camila R. Fontes-Garfias, Sujan Shresta, Sharmila Nair, Chao Shan
Publikováno v:
JCI insight, vol 6, iss 1
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
Glioblastoma multiforme (GBM) is a fatal human cancer in part because GBM stem cells are resistant to therapy and recurrence is inevitable. Previously, we demonstrated Zika virus (ZIKV) targets GBM stem cells and prevents death of mice with gliomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70a1ddc1d5cb1ac10ad87cd9a425e2b
https://escholarship.org/uc/item/00x665sr
https://escholarship.org/uc/item/00x665sr