Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jennifer G. Whisenant"'
Autor:
Kathryn E. Beckermann, MD, PhD, Christine M. Bestvina, MD, Badi El Osta, MD, Rachel E. Sanborn, MD, Hossein Borghaei, MD, Philip Edward Lammers, MD, MSCI, Giovanni Selvaggi, MD, Jennifer G. Whisenant, PhD, Ellen Heimann-Nichols, MBA, Lynne Berry, PhD, Chih-Yuan Hsu, PhD, Yu Shyr, PhD, Leora Horn, MD, MSc, MHPE, Heather Wakelee, MD, FASCO
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 2, Pp 100619- (2024)
Introduction: Targeting the tumor microenvironment may enhance response to immunotherapy (immune checkpoint inhibitors) and improve outcomes for patients. This study tested the safety and efficacy of vorolanib, a novel tyrosine kinase inhibitor of va
Externí odkaz:
https://doaj.org/article/c6b067ef1dff4f2782f2f6840a59c659
Autor:
Tuya Pal, Pamela C. Hull, Tatsuki Koyama, Phillip Lammers, Denise Martinez, Jacob McArthy, Emma Schremp, Ann Tezak, Anne Washburn, Jennifer G. Whisenant, Debra L. Friedman
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Despite lower cancer incidence rates, cancer mortality is higher among rural compared to urban dwellers. Patient, provider, and institutional level factors contribute to these disparities. The overarching objective of this study i
Externí odkaz:
https://doaj.org/article/c96d71d97bce4e38a0b3a19b9e420c10
Autor:
Deborah Cragun, Jason Beckstead, Meagan Farmer, Gillian Hooker, Marleah Dean, Ellen Matloff, Sonya Reid, Ann Tezak, Anne Weidner, Jennifer G. Whisenant, Tuya Pal
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Implementing genetic testing for inherited cancer predisposition into routine clinical care offers a tremendous opportunity for cancer prevention and early detection. However, genetic testing itself does not improve outcomes; rath
Externí odkaz:
https://doaj.org/article/d843aa1a478d468a8773fa32689c8cb2
Autor:
Christine M. Bestvina, MD, Jennifer G. Whisenant, PhD, Valter Torri, MD, Alessio Cortellini, MD, Heather Wakelee, MD, Solange Peters, MD, PhD, Elisa Roca, MD, PhD, Alessandro De Toma, MD, Fred R. Hirsch, MD, Hirva Mamdani, MD, Balazs Halmos, MD, Oscar Arrieta, MD, Anne-Cecile Metivier, MD, Mary J. Fidler, MD, Jacobo Rogado, MD, Carolyn J. Presley, MD, MHS, Celine Mascaux, MD, Carlo Genova, MD, PhD, Juan Bautista Blaquier, MD, Alfredo Addeo, MD, Giovanna Finocchiaro, MD, Hina Khan, MD, Julien Mazieres, MD, PhD, Floriana Morgillo, MD, PhD, Jair Bar, MD, Avinash Aujayeb, MBBS, Giannis Mountzios, MD, PhD, Vieri Scotti, MD, Federica Grosso, MD, Erica Geraedts, MD, Ardak N. Zhumagaliyeva, MD, PhD, Leora Horn, MD, Marina Chiara Garassino, MD, Javier Baena, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 8, Pp 100335- (2022)
Introduction: The Thoracic Centers International coronavirus disease 2019 (COVID-19) Collaboration (TERAVOLT) registry found approximately 30% mortality in patients with thoracic malignancies during the initial COVID-19 surges. Data from South Africa
Externí odkaz:
https://doaj.org/article/40def45b1dee4cd69aa88c393bc82c35
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 17-29 (2019)
The purpose of this study is to investigate imaging and histology-based measurements of intratumoral heterogeneity to evaluate early treatment response to targeted therapy in a murine model of HER2+ breast cancer. BT474 tumor-bearing mice (N = 30) we
Externí odkaz:
https://doaj.org/article/a1daa33c9f3f456ca352b3b455089c45
Autor:
Christopher G. Wood, James E. Ferguson III, Joel S. Parker, Dominic T. Moore, Jennifer G. Whisenant, Susan J. Maygarden, Eric M. Wallen, William Y. Kim, Mathew I. Milowsky, Kathryn E. Beckermann, Nancy B. Davis, Scott M. Haake, Jose A. Karam, Dante S. Bortone, Benjamin G. Vincent, Thomas Powles, W. Kimryn Rathmell
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
BACKGROUND Surgery remains the frontline therapy for patients with localized clear cell renal cell carcinoma (ccRCC); however, 20%–40% recur. Angiogenesis inhibitors have improved survival in metastatic patients and may result in responses in the n
Externí odkaz:
https://doaj.org/article/514517eaefb4496c854f9e31607be03d
Autor:
Anum K. Syed, Jennifer G. Whisenant, Stephanie L. Barnes, Anna G. Sorace, Thomas E. Yankeelov
Publikováno v:
Cancers, Vol 12, Iss 6, p 1682 (2020)
This study identifies physiological tumor habitats from quantitative magnetic resonance imaging (MRI) data and evaluates their alterations in response to therapy. Two models of breast cancer (BT-474 and MDA-MB-231) were imaged longitudinally with dif
Externí odkaz:
https://doaj.org/article/fd3c3fa8b7ff438cbb77c22e9b4bf089
Autor:
Jennifer G. Whisenant, Anna G. Sorace, J. Oliver McIntyre, Hakmook Kang, Violeta Sánchez, Mary E. Loveless, Thomas E. Yankeelov
Publikováno v:
Translational Oncology, Vol 7, Iss 6, Pp 768-779 (2014)
We report longitudinal diffusion-weighted magnetic resonance imaging (DW-MRI) and dynamic contrast enhanced (DCE)-MRI (7 T) studies designed to identify functional changes, prior to volume changes, in trastuzumab-sensitive and resistant HER2+ breast
Externí odkaz:
https://doaj.org/article/9c00aeb719bb49d1a339c692ca38ac22
Publikováno v:
Pharmaceutics, Vol 4, Iss 3, Pp 442-478 (2012)
Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) consists of the continuous acquisition of images before, during, and after the injection of a contrast agent. DCE-MRI allows for noninvasive evaluation of tumor parameters related to vasc
Externí odkaz:
https://doaj.org/article/6c0a9ff0b2ea4a2d9e6a29035006ffe2
Autor:
Jacob U. Fluckiger, Xia Li, Jennifer G. Whisenant, Todd E. Peterson, John C. Gore, Thomas E. Yankeelov
Publikováno v:
International Journal of Biomedical Imaging, Vol 2013 (2013)
We show how dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data can constrain a compartmental model for analyzing dynamic positron emission tomography (PET) data. We first develop the theory that enables the use of DCE-MRI data to sep
Externí odkaz:
https://doaj.org/article/6b7f49e31e274254aa9e6bd1ccbb5a7d