Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jennifer G. Chew"'
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
Autor:
Anoushka Joglekar, Andrey Prjibelski, Ahmed Mahfouz, Paul Collier, Susan Lin, Anna Katharina Schlusche, Jordan Marrocco, Stephen R. Williams, Bettina Haase, Ashley Hayes, Jennifer G. Chew, Neil I. Weisenfeld, Man Ying Wong, Alexander N. Stein, Simon A. Hardwick, Toby Hunt, Qi Wang, Christoph Dieterich, Zachary Bent, Olivier Fedrigo, Steven A. Sloan, Davide Risso, Erich D. Jarvis, Paul Flicek, Wenjie Luo, Geoffrey S. Pitt, Adam Frankish, August B. Smit, M. Elizabeth Ross, Hagen U. Tilgner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Alternative RNA splicing varies across the brain. Its mapping at single cell resolution is unclear. Here, the authors provide a spatial and single-cell splicing atlas reporting brain region- and cell type-specific expression of different isoforms in
Externí odkaz:
https://doaj.org/article/b27a2afb47544e009093959c837b41e3
Autor:
Vinay K. Kartha, Fabiana M. Duarte, Yan Hu, Sai Ma, Jennifer G. Chew, Caleb A. Lareau, Andrew Earl, Zach D. Burkett, Andrew S. Kohlway, Ronald Lebofsky, Jason D. Buenrostro
Publikováno v:
Cell Genomics. 2:100166
Cells require coordinated control over gene expression when responding to environmental stimuli. Here we apply scATAC-seq and single-cell RNA sequencing (scRNA-seq) in resting and stimulated human blood cells. Collectively, we generate ~91,000 single