Výsledky vyhledávání - "Jennifer Fuhr"

Akademický článek

Analysis of beta-cell maturity and mitochondrial morphology in juvenile non-human primates exposed to maternal Western-style diet during development

Autor: Darian T. Carroll, Allie Miller, Jennifer Fuhr, Joseph M. Elsakr, Valerie Ricciardi, Alexa N. Del Bene, Stedman Stephens, Evan Krystofiak, Sarah R. Lindsley, Melissa Kirigiti, Diana L. Takahashi, Tyler A. Dean, Stephanie R. Wesolowski, Carrie E. McCurdy, Jacob E. Friedman, Kjersti M. Aagaard, Paul Kievit, Maureen Gannon

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

IntroductionUsing a non-human primate (NHP) model of maternal Western-style diet (mWSD) feeding during pregnancy and lactation, we previously reported altered offspring beta:alpha cell ratio in vivo and insulin hyper-secretion ex vivo. Mitochondria a

Externí odkaz: https://doaj.org/article/2aefe612d931437fb2599f63ef8e7bf0

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Maternal Western-style diet in non-human primates leads to offspring islet adaptations including altered gene expression and insulin hypersecretion

Autor: Darian T. Carroll, Joseph M. Elsakr, Allie Miller, Jennifer Fuhr, Sarah R. Lindsley, Melissa Kirigiti, Diana L. Takahashi, Tyler A. Dean, Stephanie R. Wesolowski, Carrie E. McCurdy, Jacob E. Friedman, Kjersti M. Aagaard, Paul Kievit, Maureen Gannon

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism.

Maternal overnutrition is associated with increased susceptibility to Type 2 Diabetes in the offspring. Rodent models have shown that maternal overnutrition influences islet function in offspring. To determine whether maternal Western style diet (WSD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9aca7594e8c0dde17ae8c11e6e41aee0
https://doi.org/10.1152/ajpendo.00087.2023

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