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pro vyhledávání: '"Jennifer Farge"'
Autor:
David R. Witty, Jonathan Brand, Ho Y. Li, Paul Goldsmith, Michael Stott, Robert W. Ward, Jennifer Farge, Fiona Nimmo, Nicola Shuker, Sanjeet Singh Sehmi, Mathilde D’Angeli, Ian R. Kilford, Rio Hutchings, Jennifer Sweeting, Andrew K. Takle, John Skidmore, Hasmi Tajuddin, Michael A. Briggs, Giancarlo Trani, David Matthew Wilson, Francis Dominic Sanderson, Paula L. Nichols, David MacPherson, Stephen L. Garland, Ian D. Wall
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:1368-1372
A pharmacophore model was built, based on known CGRP receptor antagonists, and this was used to aid the identification of novel leads. Analogues were designed, modelled and synthesised which incorporated alternative 'LHS' fragments linked via either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3643131d8eb58a97f908780958aacc
https://doi.org/10.1016/j.bmcl.2010.01.012
https://doi.org/10.1016/j.bmcl.2010.01.012
