Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jennifer F. Raven"'
Autor:
Selena M. Sagan, Benoit Dupont, Jason Grebely, Mel Krajden, Sonya A. MacParland, Jennifer F. Raven, Sahar Saeed, Jordan J. Feld, D. Lorne Tyrrell, Joyce A. Wilson
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2016 (2016)
Hepatitis C virus (HCV) affects at least 268,000 Canadians and causes greater disease burden than any other infectious disease in the country. The Canadian Institutes of Health Research (CIHR) and the Public Health Agency of Canada (PHAC) have identi
Externí odkaz:
https://doaj.org/article/e18bd4232f7c4c27a0ff92cf23147dcc
Autor:
Maroun Bou Khalil, Meenakshi Sundaram, Hong-Yu Zhang, Philip H. Links, Jennifer F. Raven, Boripont Manmontri, Meltem Sariahmetoglu, Khai Tran, Karen Reue, David N. Brindley, Zemin Yao
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 1, Pp 47-58 (2009)
Phosphatidate phosphatase-1 (PAP-1) converts phosphatidate to diacylglycerol and plays a key role in the biosynthesis of phospholipids and triacylglycerol (TAG). PAP-1 activity is encoded by members of the lipin family, including lipin-1 (1α and 1β
Externí odkaz:
https://doaj.org/article/c7e2e3e0875044f584544925221558a8
Autor:
Joyce A. Wilson, Jennifer F Raven, Jordan J. Feld, Selena M. Sagan, Sonya A. MacParland, Benoît Dupont, Jason Grebely, Sahar Saeed, D. Lorne Tyrrell, Mel Krajden
Publikováno v:
Canadian Journal of Gastroenterology & Hepatology
Canadian Journal of Gastroenterology and Hepatology, Vol 2016 (2016)
Canadian Journal of Gastroenterology and Hepatology, Vol 2016 (2016)
Hepatitis C virus (HCV) affects at least 268,000 Canadians and causes greater disease burden than any other infectious disease in the country. The Canadian Institutes of Health Research (CIHR) and the Public Health Agency of Canada (PHAC) have identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5eba3c896df48c2e250cbd4c65d262
https://doi.org/10.1155/2016/5743521
https://doi.org/10.1155/2016/5743521
Autor:
James C. Richards, Kelly M. Fulton, Susan M. Twine, John S. Spika, Marc Ouellette, Jennifer F Raven, J. Wayne Conlan, Luis Barreto, Lakshmi Krishnan
Publikováno v:
Human Vaccines & Immunotherapeutics. 11:2923-2930
Vaccine biomarkers are critical to many aspects of vaccine development and licensure, including bridging findings in pre-clinical studies to clinical studies, predicting potential adverse events, and predicting vaccine efficacy. Despite advances in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c6970167267a718de55232a0629d09
https://doi.org/10.1080/21645515.2015.1083663
https://doi.org/10.1080/21645515.2015.1083663
Autor:
Jordan J. Feld, Norma Choucha, D. Lorne Tyrrell, Curtis Cooper, Louise Balfour, Jason Grebely, Selena M. Sagan, Marc Bilodeau, Marina B. Klein, Sonya A. MacParland, Mel Krajden, Frank Bialystok, Rodney S. Russell, Michael Houghton, Jennifer F Raven, Eve A. Roberts, Julie Bruneau
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 28, Iss 9, Pp 481-487 (2014)
Hepatitis C virus (HCV) currently infects approximately 250,000 individuals in Canada and causes more years of life lost than any other infectious disease in the country. In August 2011, new therapies were approved by Health Canada that have achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899b1bb82d72e64fa536a584aafe643f
https://doi.org/10.1155/2014/704919
https://doi.org/10.1155/2014/704919
Autor:
Jennifer F. Raven, Jacques Galipeau, Shala Yuan, Kathy Forner, Patrick Williams, Jessica Cuerquis, Elena Birman, Moutih Rafei, Manaf Bouchentouf
Publikováno v:
Molecular Therapy. 18(7):1293-1301
We hypothesized that fusing granulocyte-macrophage colony-stimulation factor (GMCSF) and interleukin (IL)-21 as a single bifunctional cytokine (hereafter GIFT-21) would lead to synergistic anticancer immune effects because of their respective roles i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9862094e2cb2d479c7be7b555386cab
Publikováno v:
Molecular Cancer Research. 8:798-805
The S-phase kinase-associated protein 2 (Skp2) is an F-box protein that serves as a subunit of the Skp1-Cullin-F-box ubiquitin protein ligase complex. Skp2 is overexpressed in many tumors and promotes tumor formation through its ability to induce the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d917c945628fe27fbc3a6e4982a325a
https://doi.org/10.1158/1541-7786.mcr-10-0027
https://doi.org/10.1158/1541-7786.mcr-10-0027
Publikováno v:
Cell Cycle. 7:2346-2351
The eIF2alpha kinases have been involved in the inhibition of vesicular stomatatis virus replication but the contribution of each kinase to this process has not been fully investigated. Using mouse embryonic fibroblasts (MEFs) from knock-out mice we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933784e9f29fca670996b0d6c5b49e44
https://doi.org/10.4161/cc.6323
https://doi.org/10.4161/cc.6323
Autor:
Jennifer F. Raven, Hong Qing Gao, Zineb Mounir, Antonis E. Koromilas, Shuo Wang, Andreas I. Papadakis, Dionissios Baltzis
Publikováno v:
Journal of Biological Chemistry. 283:3097-3108
Cyclin D1 plays a critical role in controlling the G(1)/S transition via the regulation of cyclin-dependent kinase activity. Several studies have indicated that cyclin D1 translation is decreased upon activation of the eukaryotic initiation factor 2a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3e55b51e79cc0ffec84aade959a8e8
https://doi.org/10.1074/jbc.m709677200
https://doi.org/10.1074/jbc.m709677200
Autor:
Shuo Wang, Jennifer F. Raven, Andrew Hoi-Tao Wong, Dionissios Baltzis, Suiyang Li, Qiaozhu Su, Antonis E. Koromilas, Li Ke Qu
Publikováno v:
EMBO reports. 8:265-270
The interferon (IFN)-inducible, double-stranded RNA activated protein kinase (PKR) is a dual-specificity kinase, which has an essential role in the regulation of protein synthesis by phosphorylating the translation eukaryotic initiation factor 2 (eIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32d6086e4fbe01376aef13c4a9f2f3a
https://doi.org/10.1038/sj.embor.7400891
https://doi.org/10.1038/sj.embor.7400891