Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jennifer F. Ma"'
Autor:
Brenda Janice Sánchez, Anne-Marie K. Tremblay, Jean-Philippe Leduc-Gaudet, Derek T. Hall, Erzsebet Kovacs, Jennifer F. Ma, Souad Mubaid, Patricia L. Hallauer, Brittany L. Phillips, Katherine E. Vest, Anita H. Corbett, Dimitris L. Kontoyiannis, Sabah N. A. Hussain, Kenneth E. M. Hastings, Sergio Di Marco, Imed-Eddine Gallouzi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
HuR is an RNA-binding protein that regulates myotube differentiation in vitro. Here, the authors show that the muscle-specific ablation of HuR in mice leads to enhanced endurance capacity and an increase in oxidative fibres by destabilising PGC1α-mR
Externí odkaz:
https://doaj.org/article/abbd8d839dcd49f5a47e7010f27a777f
Autor:
Jennifer F Ma, Brenda J Sanchez, Derek T Hall, Anne‐Marie K Tremblay, Sergio Di Marco, Imed‐Eddine Gallouzi
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 5, Pp 622-637 (2017)
Abstract Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is triggered at the late stage of many cancers. While the multifactorial nature of this syndrome and the implication of cytokines such as IL‐6, IFNγ, and
Externí odkaz:
https://doaj.org/article/1142ed7c4ec943f98c82b9c403012518
Autor:
Sergio Di Marco, Jean-Philippe Leduc-Gaudet, Jennifer F. Ma, Imed-Eddine Gallouzi, Erzsébet Nagy Kovács, Brittany L. Phillips, Anne-Marie K. Tremblay, Patricia L. Hallauer, Kenneth E. M. Hastings, Dimitris L. Kontoyiannis, Souad Mubaid, Derek T Hall, Brenda Janice Sanchez, Sabah N. A. Hussain, Katherine E. Vest, Anita H. Corbett
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
The master posttranscriptional regulator HuR promotes muscle fiber formation in cultured muscle cells. However, its impact on muscle physiology and function in vivo is still unclear. Here, we show that muscle-specific HuR knockout (muHuR-KO) mice hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215c2cbd621f6d91ed16c6cb8a4fb812
http://link.springer.com/article/10.1038/s41467-019-12186-6
http://link.springer.com/article/10.1038/s41467-019-12186-6
Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.
Autor:
Gabriela Galicia-Vázquez, Sergio Di Marco, Xian J Lian, Jennifer F Ma, Imed E Gallouzi, Jerry Pelletier
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87237 (2014)
Gene expression during muscle cell differentiation is tightly regulated at multiple levels, including translation initiation. The PI3K/mTOR signalling pathway exerts control over protein synthesis by regulating assembly of eukaryotic initiation facto
Externí odkaz:
https://doaj.org/article/0df4c202c8244fadac522a12b61024a8
Autor:
Derek T Hall, Anne-Marie K. Tremblay, Sergio Di Marco, Jennifer F. Ma, Brenda Janice Sanchez, Imed-Eddine Gallouzi
Publikováno v:
EMBO Molecular Medicine. 9:622-637
Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is triggered at the late stage of many cancers. While the multifactorial nature of this syndrome and the implication of cytokines such as IL‐6, IFNγ, and TNFα is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d1720ad017db8e774a0b23ce42d240
https://doi.org/10.15252/emmm.201607052
https://doi.org/10.15252/emmm.201607052
Autor:
Sergio Di Marco, Jennifer F. Ma, Virginie Dormoy-Raclet, Amr Omer, Scott A. Tenenbaum, Souad Mubaid, Brenda Janice Sanchez, Samantha Robinson, Imed-Eddine Gallouzi, Kholoud Ashour, Anne Cammas, Sridar V. Chittur, Xian J. Lian
Debilitating cancer-induced muscle wasting, a syndrome known as cachexia, is lethal. Here we report a posttranscriptional pathway involving the RNA-binding protein HuR as a key player in the onset of this syndrome. Under these conditions, HuR switche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba97dd8420a8f321305d36027391695
https://europepmc.org/articles/PMC6717253/
https://europepmc.org/articles/PMC6717253/
Autor:
Derek T Hall, Jason Sadek, Gregory R. Steinberg, Amr Omer, Rebecca J. Ford, Jennifer F. Ma, Simon S. Wing, Takla Griss, Brenda Janice Sanchez, Arnim Pause, Anne Marie K Tremblay, Sergio Di Marco, Nathalie Bedard, Russell G. Jones, Souad Mubaid, Imed-Eddine Gallouzi
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 7, Pp n/a-n/a (2018)
EMBO Molecular Medicine
EMBO Molecular Medicine
Activation of AMPK has been associated with pro‐atrophic signaling in muscle. However, AMPK also has anti‐inflammatory effects, suggesting that in cachexia, a syndrome of inflammatory‐driven muscle wasting, AMPK activation could be beneficial.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cde4f05d8d4a871e04e55dca505a7bc
https://doaj.org/article/a8b3c211642c4712934b7dbd386af718
https://doaj.org/article/a8b3c211642c4712934b7dbd386af718
Publikováno v:
Aging (Albany NY)
Muscle atrophy-also known as muscle wasting-is a debilitating syndrome that slowly develops with age (sarcopenia) or rapidly appears at the late stages of deadly diseases such as cancer, AIDS, and sepsis (cachexia). Despite the prevalence and the dra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577eefae470d1decc5f3bfe1f7e17aca
http://europepmc.org/articles/PMC3184974
http://europepmc.org/articles/PMC3184974
Autor:
Sergio Di Marco, Jerry Pelletier, Imed E Gallouzi, Xian J. Lian, Gabriela Galicia-Vázquez, Jennifer F. Ma
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87237 (2014)
PLoS ONE
PLoS ONE
Gene expression during muscle cell differentiation is tightly regulated at multiple levels, including translation initiation. The PI3K/mTOR signalling pathway exerts control over protein synthesis by regulating assembly of eukaryotic initiation facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602d3dee0bc2c494e423d0b259b71c50
http://europepmc.org/articles/PMC3900710?pdf=render
http://europepmc.org/articles/PMC3900710?pdf=render
Autor:
C. Von Roretz, A. M. MacRi, Imed-Eddine Gallouzi, Eveline Clair, Virginie Dormoy-Raclet, X. Jin Lian, Olivier Drouin, Jennifer F. Ma, N. Punjani
Little is known about the cellular mechanisms modulating the shift in balance from a state of survival to cell death by caspase-mediated apoptosis in response to a lethal stress. Here we show that the RNA-binding protein HuR has an important function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7bc3b6ff6f829d69f53f79385753c0
https://europepmc.org/articles/PMC3524645/
https://europepmc.org/articles/PMC3524645/