Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jennifer F. Carr"'
Autor:
Alejandro Scaffa, George A. Tollefson, Hongwei Yao, Salu Rizal, Joselynn Wallace, Nathalie Oulhen, Jennifer F. Carr, Katy Hegarty, Alper Uzun, Phyllis A. Dennery
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2135 (2022)
Heme oxygenase-1 (HO-1) is a rate-limiting enzyme in degrading heme into biliverdin and iron. HO-1 can also enter the nucleus and regulate gene transcription independent of its enzymatic activity. Whether HO-1 can alter gene expression through direct
Externí odkaz:
https://doaj.org/article/2048e9a14bad48f2bf5f2c6170590d39
Autor:
Alejandro M. Scaffa, Abigail L. Peterson, Jennifer F. Carr, David Garcia, Hongwei Yao, Phyllis A. Dennery
Publikováno v:
Physiological Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract Supplemental oxygen and mechanical ventilation commonly used in premature infants may lead to chronic lung disease of prematurity, which is characterized by arrested alveolar development and dysmorphic vascular development. Hyperoxia is also
Externí odkaz:
https://doaj.org/article/8354e6602da441fb800d393b8b296520
Autor:
Jiannan Gong, Zihang Feng, Abigail L. Peterson, Jennifer F. Carr, Xuexin Lu, Haifeng Zhao, Xiangming Ji, You-Yang Zhao, Monique E. De Paepe, Phyllis A. Dennery, Hongwei Yao
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Dysmorphic pulmonary vascular growth and abnormal endothelial cell (EC) proliferation are paradoxically observed in premature infants with bronchopulmonary dysplasia (BPD), despite vascular pruning. The pentose phosphate pathway (PPP), a metabolic pa
Externí odkaz:
https://doaj.org/article/b9f94dbb034e45fb9de9e1ca4df84791
Publikováno v:
Metabolites, Vol 10, Iss 9, p 340 (2020)
Treatments with supplemental oxygen in premature infants can impair lung development, leading to bronchopulmonary dysplasia (BPD). Although a stage-specific alteration of lung lipidome occurs during postnatal lung development, whether neonatal hypero
Externí odkaz:
https://doaj.org/article/fae9e78427e14d5385583846ae797a9e
Autor:
Phyllis A. Dennery, Abigail L. Peterson, Hongwei Yao, Jennifer F. Carr, Alejandro Scaffa, David Garcia
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Supplemental oxygen and mechanical ventilation commonly used in premature infants may lead to chronic lung disease of prematurity, which is characterized by arrested alveolar development and dysmorphic vascular development. Hyperoxia is also known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22199302a97606bffa22209638ba797
http://europepmc.org/articles/PMC8157762
http://europepmc.org/articles/PMC8157762
Autor:
Phyllis A. Dennery, Jennifer F. Carr, Abigail L. Peterson, Andrew J. Ghio, David Garcia, Alejandro Scaffa
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6941, p 6941 (2020)
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6941, p 6941 (2020)
Heme oxygenase-1 is induced by many cellular stressors and catalyzes the breakdown of heme to generate carbon monoxide and bilirubin, which confer cytoprotection. The role of HO-1 likely extends beyond the simple production of antioxidants, for examp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61326acb1458c9fb6a8bbae6a4ccf799
Autor:
Hongwei Yao, Andrew J. Ghio, David Garcia, Abigail L. Peterson, Felix Chan, Phyllis A. Dennery, Kimberlyn A Ellis, Jennifer F. Carr, Alejandro Scaffa
Publikováno v:
Pediatric research
Prolonged exposure to high oxygen concentrations in premature infants, although lifesaving, can induce lung oxidative stress and increase the risk of developing BPD, a form of chronic lung disease. The lung alveolar epithelium is damaged by sustained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857d1b392d2fc8d566a89565677e4f49
https://pubmed.ncbi.nlm.nih.gov/33144707
https://pubmed.ncbi.nlm.nih.gov/33144707
Autor:
Jennifer F. Carr, Gaurav Choudhary, Jiannan Gong, Alexander Vang, Julie Braza, Abigail L. Peterson, Hongwei Yao, Phyllis A. Dennery, Zihang Feng
Publikováno v:
J Pathol
Bronchopulmonary dysplasia (BPD), a chronic lung disease in premature infants, results from mechanical ventilation and hyperoxia, amongst other factors. Although most BPD survivors can be weaned from supplemental oxygen, many show evidence of cardiov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654d79358db3c03b12a1ee9a84a15c1f
https://pubmed.ncbi.nlm.nih.gov/32815166
https://pubmed.ncbi.nlm.nih.gov/32815166
Autor:
Jennifer F. Carr, Steven T. Gregory, Gerwald Jogl, Jacqueline L. Connetti, Albert E. Dahlberg
Publikováno v:
Journal of Bacteriology. 196:3776-3783
During protein synthesis, the ribosome undergoes conformational transitions between functional states, requiring communication between distant structural elements of the ribosome. Despite advances in ribosome structural biology, identifying the prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a3962ec2f657c19d4468d90aa5e932
https://doi.org/10.1128/jb.02104-14
https://doi.org/10.1128/jb.02104-14
Autor:
Hasan DeMirci, Steven T. Gregory, Jennifer F. Carr, Albert E. Dahlberg, Eileen L. Murphy, Gerwald Jogl, Leyi Wang, Frank V. Murphy, Scott C. Blanchard
Publikováno v:
RNA. 19:1791-1801
The ribosome decodes mRNA by monitoring the geometry of codon–anticodon base-pairing using a set of universally conserved 16S rRNA nucleotides within the conformationally dynamic decoding site. By applying single-molecule FRET and X-ray crystallogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea09d1f1b894b09afb6a558009f9492f
https://doi.org/10.1261/rna.040030.113
https://doi.org/10.1261/rna.040030.113