Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jennifer E. Snyder-Cappione"'
Autor:
Anna C. Belkina, Christopher O. Ciccolella, Rina Anno, Richard Halpert, Josef Spidlen, Jennifer E. Snyder-Cappione
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Visualisation tools that use dimensionality reduction, such as t-SNE, provide poor visualisation on large data sets of millions of observations. Here the authors present opt-SNE, that automatically finds data set-tailored parameters for t-SNE to opti
Externí odkaz:
https://doaj.org/article/e5126a248205487bb5a7c54c11c0bcc3
Autor:
Rachel R. Yuen, Dylan Steiner, Riley M.F. Pihl, Elizabeth Chavez, Alex Olson, Erika L. Smith, Lillia A. Baird, Filiz Korkmaz, Patricia Urick, Manish Sagar, Jacob L. Berrigan, Suryaram Gummuluru, Ronald B. Corley, Karen Quillen, Anna C. Belkina, Gustavo Mostoslavsky, Ian R. Rifkin, Yachana Kataria, Amedeo J. Cappione, Wenda Gao, Nina H. Lin, Nahid Bhadelia, Jennifer E. Snyder-Cappione
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The COVID-19 pandemic has drastically impacted work, economy, and way of life. Sensitive measurement of SARS-CoV-2 specific antibodies would provide new insight into pre-existing immunity, virus transmission dynamics, and the nuances of SARS-CoV-2 pa
Externí odkaz:
https://doaj.org/article/a872479249714dd78bd7bc72df044446
Autor:
Hisashi Akiyama, Caitlin M. Miller, Chelsea R. Ettinger, Anna C. Belkina, Jennifer E. Snyder-Cappione, Suryaram Gummuluru
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Type I Interferon is thought to be a driving force for immune activation and T cell exhaustion during HIV infection. Here the authors show that intron-containing HIV RNA induces innate immune activation resulting in associated T cell dysfunction.
Externí odkaz:
https://doaj.org/article/fd9ffab4b9f44e5a8e33aca631a09672
Autor:
Vinay K. Kartha, Khalid A. Alamoud, Khikmet Sadykov, Bach-Cuc Nguyen, Fabrice Laroche, Hui Feng, Jina Lee, Sara I. Pai, Xaralabos Varelas, Ann Marie Egloff, Jennifer E. Snyder-Cappione, Anna C. Belkina, Manish V. Bais, Stefano Monti, Maria A. Kukuruzinska
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy characterized by tumor heterogeneity, locoregional metastases, and resistance to existing treatments. Although a number of genomic and molecular alterations
Externí odkaz:
https://doaj.org/article/3f10be2b6404420f97878bd8174c79b8
Autor:
Anna C. Belkina, Alina Starchenko, Katherine A. Drake, Elizabeth A. Proctor, Riley M. F. Pihl, Alex Olson, Douglas A. Lauffenburger, Nina Lin, Jennifer E. Snyder-Cappione
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Even with effective viral control, HIV-infected individuals are at a higher risk for morbidities associated with older age than the general population, and these serious non-AIDS events (SNAEs) track with plasma inflammatory and coagulation markers.
Externí odkaz:
https://doaj.org/article/d1fc0836ebcf4f9f8977fd08f1ccad79
Publikováno v:
Cells, Vol 1, Iss 2, Pp 89-99 (2012)
Mycobacterium tuberculosis (MTB) is a global heath epidemic, its threat amplified by HIV infection and the emergence of multidrug-resistant tuberculosis (MDR-TB). Interferon (IFN)-gamma release assays (IGRAs) have improved the accuracy of detection o
Externí odkaz:
https://doaj.org/article/e5fd71c3010f44618e22f4bc22e1f338
Autor:
Nahid Bhadelia, Alex Olson, Erika Smith, Katherine Riefler, Jacob Cabrejas, Maria-Jose Ayuso, Katherine Clarke, Rachel R. Yuen, Nina H. Lin, Zachary J. Manickas-Hill, Ian Rifkin, Andreea Bujor, Manish Sagar, Anna C. Belkina, Jennifer E. Snyder-Cappione
High autoantibody levels are found in individuals hospitalized for COVID-19. The temporal trajectories and levels of these autoantibodies months into convalescence after SARS-CoV-2 infection are unclear. It is also unknown if the composite autoantibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8a36fede5f55ca98531f4416daab97e
https://doi.org/10.1101/2022.05.04.22274681
https://doi.org/10.1101/2022.05.04.22274681
Autor:
Jennifer E. Snyder-Cappione, J.J. Lee, Chloe Habib, S. Kim, Jordan Carr, Hatice Hasturk, M. Cleveland, Barbara S. Nikolajczyk, Anna C. Belkina, H.H. Elgaali, Riley M.F. Pihl, M. Azer
Publikováno v:
J Dent Res
Periodontitis (PD) is a common source of uncontrolled inflammation in obesity-associated type 2 diabetes (T2D). PD apparently fuels the inflammation of T2D and associates with poor glycemic control and increased T2D morbidity. New therapeutics are cr
Autor:
Josef Spidlen, Rina Anno, Anna C. Belkina, Christopher O. Ciccolella, Jennifer E. Snyder-Cappione, Richard Halpert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Accurate and comprehensive extraction of information from high-dimensional single cell datasets necessitates faithful visualizations to assess biological populations. A state-of-the-art algorithm for non-linear dimension reduction, t-SNE, requires mu
Autor:
Nahid Bhadelia, Wenda Gao, Anna C. Belkina, Amedeo Cappione, Jacob Berrigan, Erika L Smith, Elizabeth Chavez, Ian R. Rifkin, Patricia Urick, Gustavo Mostoslavsky, Jennifer E. Snyder-Cappione, Alex Olson, Filiz Korkmaz, Ronald B. Corley, Suryaram Gummuluru, Riley M.F. Pihl, Manish Sagar, L. Baird, Nina Lin, Dylan Steiner, Karen Quillen, Yachana Kataria, Rachel Yuen
The COVID-19 pandemic has significantly impacted work, economy, and way of life. The SARS-CoV-2 virus displays unique features including widely varying symptoms and outcomes between infected individuals. Sensitive measurement of SARS-CoV-2 specific a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c80d0defb215a3073ecb4af9d8ffd582
https://doi.org/10.1101/2020.09.15.20192765
https://doi.org/10.1101/2020.09.15.20192765