Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jennifer E. Nelson"'
Autor:
Jennifer E. Nelson, Simon C. C. Lucas, Iacovos N Michaelides, Matthias R. Bauer, Benjamin C Whitehurst, R. Ian Storer, Paolo Di Fruscia
Publikováno v:
RSC Med Chem
Aliphatic three- and four-membered rings including cyclopropanes, cyclobutanes, oxetanes, azetidines and bicyclo[1.1.1]pentanes have been increasingly exploited in medicinal chemistry for their beneficial physicochemical properties and applications a
Autor:
Justin M Greene, Emily N Chin, Melisa L Budde, Jennifer J Lhost, Paul J Hines, Benjamin J Burwitz, Karl W Broman, Jennifer E Nelson, Thomas C Friedrich, David H O'Connor
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43690 (2012)
The presence of certain MHC class I alleles is correlated with remarkable control of HIV and SIV, indicating that specific CD8 T cell responses can effectively reduce viral replication. It remains unclear whether epitopic breadth is an important feat
Externí odkaz:
https://doaj.org/article/959eeb45e7fd4d15941657eb9c3e824a
Nature has a remarkable ability to carry out site-selective post-translational modification of proteins, therefore enabling a marked increase in their functional diversity1. Inspired by this, chemical tools have been developed for the synthetic manip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89aa1175c587dcbd3262f712164b3ee9
https://www.repository.cam.ac.uk/handle/1810/290467
https://www.repository.cam.ac.uk/handle/1810/290467
Autor:
William McCoull, Roman D. Abrams, Erica Anderson, Kevin Blades, Peter Barton, Matthew Box, Jonathan Burgess, Kate Byth, Qing Cao, Claudio Chuaqui, Rodrigo J. Carbajo, Tony Cheung, Erin Code, Andrew D. Ferguson, Shaun Fillery, Nathan O. Fuller, Eric Gangl, Ning Gao, Matthew Grist, David Hargreaves, Martin R. Howard, Jun Hu, Paul D. Kemmitt, Jennifer E. Nelson, Nichole O’Connell, D. Bryan Prince, Piotr Raubo, Philip B. Rawlins, Graeme R. Robb, Junjie Shi, Michael J. Waring, David Whittaker, Marta Wylot, Xiahui Zhu
Publikováno v:
Journal of medicinal chemistry. 60(14)
Autor:
Jennifer E. Nelson, Graeme R. Robb, Martin R. Howard, Piotr Raubo, Paul D. Kemmitt, Kevin Blades, Junjie Shi, Tony Cheung, Qing Cao, Peter Barton, Andrew D. Ferguson, D. Bryan Prince, Shaun M. Fillery, Jun Hu, David J. Hargreaves, Roman D. Abrams, Nathan O. Fuller, Claudio Chuaqui, Eric Gangl, Matthew R. Box, Ning Gao, William McCoull, Kate Byth, Michael J. Waring, Jonathan Burgess, Xiahui Zhu, Matthew Grist, Erica Anderson, Nichole O'Connell, Philip B. Rawlins, Marta Wylot, David Whittaker, Rodrigo J. Carbajo, Erin Code
Publikováno v:
Journal of medicinal chemistry. 60(10)
Inhibition of the protein-protein interaction between B-cell lymphoma 6 (BCL6) and corepressors has been implicated as a therapeutic target in diffuse large B-cell lymphoma (DLBCL) cancers and profiling of potent and selective BCL6 inhibitors are cri
Autor:
Stephen P. Thomas, G. Usherwood Sloan, Alan Ironmonger, Ming-Ming Tran, Jennifer E. Nelson, Alistair J. MacNair
Publikováno v:
MacNair, A J, Ming-Ming Tran, N V, Nelson, J E, Sloan, G U, Ironmonger, A & Thomas, S P 2014, ' Iron-catalysed, general and operationally simple formal hydrogenation using Fe(OTf)(3) and NaBH4 ', Organic & Biomolecular chemistry, vol. 12, no. 28, pp. 5082-5088 . https://doi.org/10.1039/c4ob00945b
An operationally simple and environmentally benign formal hydrogenation protocol has been developed using highly abundant iron (III) salts and an inexpensive, bench stable, stoichiometric reductant, NaBH4, in ethanol, under ambient conditions. This r
Publikováno v:
Circulation. 132
Introduction: Advances in surgical and medical therapies have increased the life expectancy for patients with congenital heart disease. Arrhythmias in these patients are common and multi-factorial, often due to a disruption of the hearts’ intrinsic
Autor:
Jennifer E. Nelson, Stephen P. Thomas, G. Usherwood Sloan, Ming-Ming Tran, Alistair J. MacNair, Alan Ironmonger
Publikováno v:
ChemInform. 45
Autor:
Paul J. Hines, Benjamin J. Burwitz, Jennifer E. Nelson, Justin M. Greene, David H. O’Connor, Karl W. Broman, Melisa L. Budde, Thomas C. Friedrich, Jennifer J. Lhost, Emily N. Chin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e43690 (2012)
PLoS ONE, Vol 7, Iss 8, p e43690 (2012)
The presence of certain MHC class I alleles is correlated with remarkable control of HIV and SIV, indicating that specific CD8 T cell responses can effectively reduce viral replication. It remains unclear whether epitopic breadth is an important feat