Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jennifer E. Holdway"'
Autor:
Todd F. Roberts, Danyal H. Alam, Marissa Co, Massimo Trusel, Vamsi Daliparthi, Jennifer E. Holdway, Fatma Ayhan, Therese M. I. Koch, Francisco Garcia-Oscos, Harshida Pancholi, Genevieve Konopka
Autism spectrum disorders (ASD) are characterized by impaired learning of culturally transmitted behaviors like social skills, speech, and language1–3. These behaviors are learned by copying parents and other social models during development, a two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b662691cf57c3364f7f01c2582da2a1
Autor:
Kenneth D. Poss, Matthew Gemberling, Wen-Yee Choi, Jennifer E. Holdway, Rolf O. Karlstrom, Jinhu Wang, Meng-Chieh Shen
Publikováno v:
Development. 140:660-666
Adult mammalian cardiomyocytes have little capacity to proliferate in response to injury, a deficiency that underlies the poor regenerative ability of human hearts after myocardial infarction. By contrast, zebrafish regenerate heart muscle after trau
Publikováno v:
Developmental Cell. 22:879-886
SummaryDetermining the cellular source of new skeletal elements is critical for understanding appendage regeneration in amphibians and fish. Recent lineage-tracing studies indicated that zebrafish fin ray bone regenerates through the dedifferentiatio
Autor:
Gregory F. Egnaczyk, Andreas A. Werdich, Ryan M. Anderson, Kazu Kikuchi, Yi Fang, Didier Y.R. Stainier, Todd Evans, Calum A. MacRae, Jennifer E. Holdway, Kenneth D. Poss
Publikováno v:
Nature. 464:601-605
Recent studies indicate that mammals, including humans, maintain some capacity to renew cardiomyocytes throughout postnatal life. Yet, there is little or no significant cardiac muscle regeneration after an injury such as acute myocardial infarction.
Publikováno v:
Development. 135:183-192
The heart maintains structural and functional integrity during years of continual contraction, but the extent to which new cell creation participates in cardiac homeostasis is unclear. Here, we assessed cellular and molecular mechanisms of cardiac ho
Autor:
Calum A. MacRae, Andreas A. Werdich, Jinhu Wang, Daniela Panáková, Deborah Yelon, Jennifer E. Holdway, Amy L. Dickson, Sumeet Pal Singh, Kazu Kikuchi, Yi-Fan Lin, Kenneth D. Poss, Matthew Gemberling, M. Khaled Sabeh, James S. Burris
Publikováno v:
Development (Cambridge, England). 138(16)
Natural models of heart regeneration in lower vertebrates such as zebrafish are based on invasive surgeries causing mechanical injuries that are limited in size. Here, we created a genetic cell ablation model in zebrafish that facilitates inducible d
Autor:
Jennifer E. Holdway, Airon A. Wills, Jinhu Wang, Vikas Gupta, Kazu Kikuchi, Kenneth D. Poss, Yi Fang
Publikováno v:
Development (Cambridge, England). 138(14)
Recent lineage-tracing studies have produced conflicting results about whether the epicardium is a source of cardiac muscle cells during heart development. Here, we examined the developmental potential of epicardial tissue in zebrafish during both em
Publikováno v:
Mechanisms of Development. 126:S46