Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jennifer E. Cowan"'
Autor:
Jennifer E. Cowan, Justin Malin, Yongge Zhao, Mina O. Seedhom, Christelle Harly, Izumi Ohigashi, Michael Kelly, Yousuke Takahama, Jonathan W. Yewdell, Maggie Cam, Avinash Bhandoola
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Thymic epithelial cells (TEC) are essential for the maturation of functional T cells, while thymus size is proportional to the overall output efficiency. Here the authors show, using transcriptome analyses, that mouse fetal TEC maintain a Myc-depende
Externí odkaz:
https://doaj.org/article/784327815c984356aac217a9fbd2ed1e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b8f43de353754ee79eb6ffd60dac62fa
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Thymus involution occurs in all vertebrates. It is thought to impact on immune responses in the aged, and in other clinical circumstances such as bone marrow transplantation. Determinants of thymus growth and size are beginning to be identified. Ecto
Externí odkaz:
https://doaj.org/article/c993fea9a7bb4a5ead83c786d4468663
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1041-1048 (2016)
Summary: Current models of Foxp3+ regulatory T cell (Treg) development involve CCR7-mediated migration of thymocytes into the thymus medulla to enable essential interactions with medullary epithelium. However, increased Foxp3+ thymic Treg numbers in
Externí odkaz:
https://doaj.org/article/a3f7e5b6fef74e41aca77d559c4a1414
Publikováno v:
T-Cell Development ISBN: 9781071627396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9250a5090a931f694f03cb390cec953d
https://doi.org/10.1007/978-1-0716-2740-2_2
https://doi.org/10.1007/978-1-0716-2740-2_2
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Autor:
Jennifer E. Cowan
Publikováno v:
Nature
Humans and their microbiota have coevolved a mutually beneficial relationship in which the human host provides a hospitable environment for the microorganisms and the microbiota provides many advantages for the host, including nutritional benefits an
Autor:
Andrea J. White, Graham Anderson, Kathryn Fountain, Victor L. J. Tybulewicz, Jennifer E. Cowan, Probir Chakravarty, Harald Hartweger, Lesley Vanes, Miriam Llorian Sopena, Robert Köchl
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
WNK1, a kinase that controls kidney salt homeostasis, also regulates adhesion and migration in CD4+ T cells. Wnk1 is highly expressed in thymocytes, and since migration is important for thymocyte maturation, we investigated a role for WNK1 in mouse t
Autor:
Probir Chakravarty, Lesley Vanes, Harald Hartweger, Victor L. J. Tybulewicz, Andrea J. White, Kathryn Fountain, Miriam Llorian Sopena, Jennifer E. Cowan, Graham Anderson, Robert Köchl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5708a3a9e9930368c67ee47a19854f9
https://doi.org/10.7554/elife.56934.sa2
https://doi.org/10.7554/elife.56934.sa2
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Thymus involution occurs in all vertebrates. It is thought to impact on immune responses in the aged, and in other clinical circumstances such as bone marrow transplantation. Determinants of thymus growth and size are beginning to be identified. Ecto