Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jennifer E. Bestman"'
Autor:
Aaron C Ta, Lin-Chien Huang, Caroline R McKeown, Jennifer E Bestman, Kendall Van Keuren-Jensen, Hollis T Cline
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
AbstractAmphibian metamorphosis is a transitional period that involves significant changes in the cell-type populations and biological processes occurring in the brain. Analysis of gene expression dynamics during this process may provide insight into
Externí odkaz:
https://doaj.org/article/a984f1b90ab846af9770d9317221f626
Publikováno v:
Cold Spring Harb Protoc
Notable for producing ATP via oxidative phosphorylation, mitochondria also control calcium homeostasis, lipogenesis, the regulation of reactive oxygen species, and apoptosis. Even within relatively simple cells, mitochondria are heterogeneous with re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::097ca88f4028805ace2385b5c8bbd48a
https://pubmed.ncbi.nlm.nih.gov/33795462
https://pubmed.ncbi.nlm.nih.gov/33795462
Autor:
Jennifer E Bestman, Hollis Cline
Publikováno v:
Frontiers in Neural Circuits, Vol 3 (2009)
Cytoplasmic Polyadenylation Element Binding protein (CPEB) is an RNA binding protein involved in dendritic delivery of mRNA and activity-dependent, polyadenylation-induced translation of mRNAs in the dendritic arbor. CPEB affects learning and memory
Externí odkaz:
https://doaj.org/article/ad1504829c104e9199875d99e457b70f
Autor:
Jennifer E. Bestman, Hollis T. Cline
Publikováno v:
Methods in Molecular Biology ISBN: 9781493997312
Methods in Molecular Biology ISBN: 9781627036542
Methods in Molecular Biology ISBN: 9781627036542
Antisense morpholino oligonucleotides (MOs) have become a valuable method to knockdown protein levels, to block with mRNA splicing and to interfere with miRNA function. MOs are widely used to alter gene expression in development of Xenopus and Zebraf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7bd47bb8fdf4027f8a322a1f8059d9
https://doi.org/10.1007/978-1-4939-9732-9_21
https://doi.org/10.1007/978-1-4939-9732-9_21
Publikováno v:
Developmental biology
Neurogenesis in the brain of Xenopus laevis continues throughout larval stages of development. We developed a 2-tier screen to identify candidate genes controlling neurogenesis in Xenopus optic tectum in vivo. First, microarray and NanoString analyse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8af57495ef46b8776b5bff83fd45a4
https://doi.org/10.1016/j.ydbio.2015.03.010
https://doi.org/10.1016/j.ydbio.2015.03.010
Publikováno v:
Nucleic Acids Research
DNA polymerase gamma (POLG) is essential for replication and repair of mitochondrial DNA (mtDNA). Mutations in POLG cause mtDNA instability and a diverse range of poorly understood human diseases. Here, we created a unique Polg animal model, by modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e1ad06da09c61ca541842706864a25
http://europepmc.org/articles/PMC4666367
http://europepmc.org/articles/PMC4666367
Autor:
Krista D. Stackley, Sherine S.L. Chan, Tucker Williamson, Jennifer J. Rahn, Jennifer E. Bestman
Publikováno v:
Differentiation. 89:51-69
The etiology of mitochondrial disease is poorly understood. Furthermore, treatment options are limited, and diagnostic methods often lack the sensitivity to detect disease in its early stages. Disrupted oxidative phosphorylation (OXPHOS) that inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878a43b2da8f2c987eea96b3624f33e9
https://doi.org/10.1016/j.diff.2015.01.001
https://doi.org/10.1016/j.diff.2015.01.001
Autor:
Jennifer J. Rahn, C.J. Chou, Benjamin J. Josey, E.S. Inks, Sherine S.L. Chan, Krista D. Stackley, Jennifer E. Bestman, C.E. Rogers
Publikováno v:
Neuroscience. 259:142-154
Epilepsy is a debilitating disease affecting 1-2% of the world's population. Despite this high prevalence, 30% of patients suffering from epilepsy are not successfully managed by current medication suggesting a critical need for new anti-epileptic dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333248068f141ffa4cb9a2fa5047c7d6
https://doi.org/10.1016/j.neuroscience.2013.11.040
https://doi.org/10.1016/j.neuroscience.2013.11.040
Publikováno v:
The Journal of Comparative Neurology. 520:401-433
We analyzed the function of neural progenitors in the developing central nervous system of Xenopus laevis tadpoles by using in vivo time-lapse confocal microscopy to collect images through the tectum at intervals of 2–24 hours over 3 days. Neural p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47d3eef48e94a77fb27bc30b56aa45c
https://doi.org/10.1002/cne.22795
https://doi.org/10.1002/cne.22795
Autor:
Steven M. Claypool, Oleh Khalimonchuk, Jennifer E. Bestman, Robert E. Lewis, Rodrigo Franco, Krista D. Stackley, Jennifer J. Rahn, Sherine S.L. Chan, Mario R. Fernandez, Annadurai Anandhan, Iryna Bohovych
Publikováno v:
Scientific Reports
Mitochondria are involved in key cellular functions including energy production, metabolic homeostasis and apoptosis. Normal mitochondrial function is preserved by several interrelated mechanisms. One mechanism – intramitochondrial quality control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce001e362b263eb50c6748627f4d415