Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Jennifer E, Ho"'
Autor:
James P. Pirruccello, Paolo Di Achille, Seung Hoan Choi, Joel T. Rämö, Shaan Khurshid, Mahan Nekoui, Sean J. Jurgens, Victor Nauffal, Shinwan Kany, FinnGen, Kenney Ng, Samuel F. Friedman, Puneet Batra, Kathryn L. Lunetta, Aarno Palotie, Anthony A. Philippakis, Jennifer E. Ho, Steven A. Lubitz, Patrick T. Ellinor
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Increased left atrial volume and decreased left atrial function have long been associated with atrial fibrillation. The availability of large-scale cardiac magnetic resonance imaging data paired with genetic data provides a unique opportunit
Externí odkaz:
https://doaj.org/article/28dcb362d1d747399f72a9d9686b4b32
Autor:
Suzanne Oskouie, MD, Ambarish Pandey, MD, MSCS, Andrew J. Sauer, MD, Stephen J. Greene, MD, Wilfried Mullens, MD, PhD, Muhammad Shahzeb Khan, MD, MSc, Kieran L. Quinn, MD, PhD, Jennifer E. Ho, MD, Nancy M. Albert, PhD, Harriette GC. Van Spall, MD, MPH
Publikováno v:
JACC: Advances, Vol 3, Iss 9, Pp 101131- (2024)
Heart failure (HF) is a leading cause of hospitalization in older adults. Patients are at high risk of readmission and death following hospitalization for HF. There is no standard approach of health care delivery during the hospital-to-home transitio
Externí odkaz:
https://doaj.org/article/76cf31bffd3d4d7f8467f0476677e04d
Autor:
Emily S. Lau, Yunong Zhao, Emelia J. Benjamin, Vasan S. Ramachandran, Vanessa Xanthakis, Susan Cheng, Jennifer E. Ho
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Externí odkaz:
https://doaj.org/article/44915bad2a2a4eb2ab01468e50016fca
Autor:
Emily S. Lau, Athar Roshandelpoor, Shahrooz Zarbafian, Dongyu Wang, James S. Guseh, Norrina Allen, Vinithra Varadarajan, Matthew Nayor, Ravi V. Shah, Joao A. C. Lima, Sanjiv J. Shah, Bing Yu, Mona Alotaibi, Susan Cheng, Mohit Jain, Gregory D. Lewis, Jennifer E. Ho
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Systemic inflammation has been implicated in the pathobiology of heart failure with preserved ejection fraction (HFpEF). Here, we examine the association of upstream mediators of inflammation as ascertained by fatty-acid derived eicosanoid a
Externí odkaz:
https://doaj.org/article/07f73b5e0093461e99f48c002b887e3d
Autor:
Ravi V. Shah, Shih‐Jen Hwang, Venkatesh L. Murthy, Shilin Zhao, Kahraman Tanriverdi, Priya Gajjar, Kevin Duarte, Mark Schoenike, Robyn Farrell, Liana C. Brooks, Deepa M. Gopal, Jennifer E. Ho, Nicholas Girerd, Ramachandran S. Vasan, Daniel Levy, Jane E. Freedman, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background While exercise impairments are central to symptoms and diagnosis of heart failure with preserved ejection fraction (HFpEF), prior studies of HFpEF biomarkers have mostly focused on resting phenotypes. We combined precise exercise phenotype
Externí odkaz:
https://doaj.org/article/2306c9218f714b4c81c636939db51d48
Autor:
Gillian Murtagh, James L. Januzzi, Marielle Scherrer‐Crosbie, Tomas G. Neilan, Susan Dent, Jennifer E. Ho, Vinesh Appadurai, Ray McDermott, Nausheen Akhter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
ABSTRACT Cardiotoxicity is a growing concern in the oncology population. Transthoracic echocardiography and multigated acquisition scans have been used for surveillance but are relatively insensitive and resource intensive. Innovative imaging techniq
Externí odkaz:
https://doaj.org/article/fff5d80966a54a05b23e19381cc66a9c
Autor:
Shaan Khurshid, Julieta Lazarte, James P. Pirruccello, Lu-Chen Weng, Seung Hoan Choi, Amelia W. Hall, Xin Wang, Samuel F. Friedman, Victor Nauffal, Kiran J. Biddinger, Krishna G. Aragam, Puneet Batra, Jennifer E. Ho, Anthony A. Philippakis, Patrick T. Ellinor, Steven A. Lubitz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
A genome-wide association study of cardiac magnetic resonance-derived left ventricular mass index including 43,000 UK Biobank participants reveals 12 associations (11 novel), implicating genes involved in cardiac contractility and cardiomyopathy.
Externí odkaz:
https://doaj.org/article/1a8e275a72c04f6d9ede2ed763e2d9bc
Autor:
Mariana F. Ramirez, Michael Honigberg, Dongyu Wang, Juhi K. Parekh, Kamila Bielawski, Paul Courchesne, Martin D. Larson, Daniel Levy, Joanne M. Murabito, Jennifer E. Ho, Emily S. Lau
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 16 (2023)
Background Premature and early menopause are independently associated with greater risk of cardiovascular disease (CVD). However, mechanisms linking age of menopause with CVD remain poorly characterized. Methods and Results We measured 71 circulating
Externí odkaz:
https://doaj.org/article/811f832177584edd8aa262d80a8022bf
Autor:
Christy N. Taylor, Dongyu Wang, Martin G. Larson, Emily S. Lau, Emelia J. Benjamin, Ralph B. D'Agostino, Ramachandran S. Vasan, Daniel Levy, Susan Cheng, Jennifer E. Ho
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 6 (2023)
Background A parental history of cardiovascular disease (CVD) confers greater risk of future CVD among offspring. Whether the presence of parental modifiable risk factors contribute to or modify CVD risk in offspring is unclear. Methods and Results W
Externí odkaz:
https://doaj.org/article/31f09a8ec0494dee92d39e1c463e656d
Autor:
Shaan Khurshid, Christopher Reeder, Lia X. Harrington, Pulkit Singh, Gopal Sarma, Samuel F. Friedman, Paolo Di Achille, Nathaniel Diamant, Jonathan W. Cunningham, Ashby C. Turner, Emily S. Lau, Julian S. Haimovich, Mostafa A. Al-Alusi, Xin Wang, Marcus D. R. Klarqvist, Jeffrey M. Ashburner, Christian Diedrich, Mercedeh Ghadessi, Johanna Mielke, Hanna M. Eilken, Alice McElhinney, Andrea Derix, Steven J. Atlas, Patrick T. Ellinor, Anthony A. Philippakis, Christopher D. Anderson, Jennifer E. Ho, Puneet Batra, Steven A. Lubitz
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-14 (2022)
Abstract Electronic health record (EHR) datasets are statistically powerful but are subject to ascertainment bias and missingness. Using the Mass General Brigham multi-institutional EHR, we approximated a community-based cohort by sampling patients r
Externí odkaz:
https://doaj.org/article/cee0e785728d44acb66d820bf455a8f1