Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jennifer Dorrens"'
Autor:
Luise A. Seeker, Sarah L. Underwood, Rachael V. Wilbourn, Jennifer Dorrens, Hannah Froy, Rebecca Holland, Joanna J. Ilska, Androniki Psifidi, Ainsley Bagnall, Bruce Whitelaw, Mike Coffey, Georgios Banos, Daniel H. Nussey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Telomere length is predictive of adult health and survival across vertebrate species. However, we currently do not know whether such associations result from among-individual differences in telomere length determined genetically or by early-
Externí odkaz:
https://doaj.org/article/ab6c6709e3b64eb4a9068e831fb649dc
Autor:
Michael A.S. Taboski, David C.F. Sealey, Jennifer Dorrens, Chandrakant Tayade, Dean H. Betts, Lea Harrington
Publikováno v:
Cell Reports, Vol 1, Iss 2, Pp 91-98 (2012)
Despite the importance of telomere maintenance in cancer cell survival via the elongation of telomeres by telomerase reverse transcriptase (TERT) or alternative lengthening of telomeres (ALT), it had not been tested directly whether telomere maintena
Externí odkaz:
https://doaj.org/article/60ffbb45b53d46488b9f7e62a4031ee5
Autor:
Hannah Froy, Kathryn A. Watt, Lea Harrington, Jill G. Pilkington, Daniel H. Nussey, Rachael V. Wilbourn, Josephine M. Pemberton, Luise A. Seeker, Sarah L. Underwood, Jennifer Dorrens
Publikováno v:
Proc Natl Acad Sci U S A
Froy, H, Underwood, S, Dorrens, J, Seeker, L, Watt, K, Wilbourn, R, Pilkington, J, Harrington, L, Pemberton, J M & Nussey, D H 2021, ' Heritable variation in telomere length predicts mortality in soay sheep ', Proceedings of the National Academy of Sciences, vol. 118, no. 15, e2020563118 . https://doi.org/10.1073/pnas.2020563118
Froy, H, Underwood, S, Dorrens, J, Seeker, L, Watt, K, Wilbourn, R, Pilkington, J, Harrington, L, Pemberton, J M & Nussey, D H 2021, ' Heritable variation in telomere length predicts mortality in soay sheep ', Proceedings of the National Academy of Sciences, vol. 118, no. 15, e2020563118 . https://doi.org/10.1073/pnas.2020563118
Telomere length (TL) is considered an important biomarker of whole-organism health and ageing. Across humans and other vertebrates, short telomeres are associated with increased subsequent mortality risk, but the processes responsible for this correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54aa9e49da01bbe9f466e81f53b4a99c
https://pubmed.ncbi.nlm.nih.gov/33876756
https://pubmed.ncbi.nlm.nih.gov/33876756
Autor:
Kathryn A. Watt, Jill G. Pilkington, Sanjana Ravindran, Hannah Froy, Josephine M. Pemberton, Lea Harrington, Jennifer Dorrens, Sarah L. Underwood, Daniel H. Nussey, Rachael V. Wilbourn, Luise A. Seeker
Publikováno v:
Ravindran, S, Froy, H, Underwood, S L, Dorrens, J, Seeker, L A, Watt, K, Wilbourn, R V, Pilkington, J G, Harrington, L, Pemberton, J M & Nussey, D H 2021, ' The association between female reproductive performance and leukocyte telomere length in wild Soay sheep ', Molecular Ecology . https://doi.org/10.1111/mec.16175
Telomere length (TL), typically measured across a sample of blood cells, has emerged as an exciting potential marker of physiological state and of the costs of investment in growth and reproduction within evolutionary ecology. While there is mounting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236becae9ef748271613d651bcb75256
https://pubmed.ncbi.nlm.nih.gov/34514660
https://pubmed.ncbi.nlm.nih.gov/34514660
Autor:
Laura Ross, Hannah Lemon, Andrés G de la Filia, Jennifer Dorrens, Dominik R. Laetsch, Andrew J. Mongue
Publikováno v:
Molecular Biology and Evolution
Garcia De La Filia Molina, A, Mongue, A, Dorrens, J, Lemon, H, Laetsch, D R & Ross, L 2021, ' Males that silence their father’s genes : Genomic imprinting of a complete haploid genome ', Molecular Biology and Evolution, vol. 38, no. 6, msab052, pp. 2566–2581 . https://doi.org/10.1093/molbev/msab052
Garcia De La Filia Molina, A, Mongue, A, Dorrens, J, Lemon, H, Laetsch, D R & Ross, L 2021, ' Males that silence their father’s genes : Genomic imprinting of a complete haploid genome ', Molecular Biology and Evolution, vol. 38, no. 6, msab052, pp. 2566–2581 . https://doi.org/10.1093/molbev/msab052
Genetic conflict is considered a key driver in the evolution of new reproductive and sex determining systems. In particular, reproductive strategies with non-Mendelian inheritance, where parents do not contribute equally to the genetic makeup of thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feae7ea684a215fea0db4fafd427b24f
Autor:
Androniki Psifidi, Rebecca Holland, Daniel H. Nussey, Mike Coffey, Joanna J. Ilska, Bruce Whitelaw, Rachael V. Wilbourn, Luise A. Seeker, Jennifer Dorrens, Georgios Banos, Ainsley Bagnall, Hannah Froy, Sarah L. Underwood
Publikováno v:
Scientific Reports
Seeker, L, Underwood, S, Wilbourn, R, Dorrens, J, Froy, H, Holland, R, Ilska, J J, Psifidi, A, Bagnall, A, Whitelaw, B, Nussey, D H, Coffey, M & Banos, G 2021, ' Telomere attrition rates are associated with weather conditions and predict productive lifespan in dairy cattle ', Scientific Reports, vol. 11, 5589 . https://doi.org/10.1038/s41598-021-84984-2
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Seeker, L, Underwood, S, Wilbourn, R, Dorrens, J, Froy, H, Holland, R, Ilska, J J, Psifidi, A, Bagnall, A, Whitelaw, B, Nussey, D H, Coffey, M & Banos, G 2021, ' Telomere attrition rates are associated with weather conditions and predict productive lifespan in dairy cattle ', Scientific Reports, vol. 11, 5589 . https://doi.org/10.1038/s41598-021-84984-2
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Telomere length is predictive of adult health and survival across vertebrate species. However, we currently do not know whether such associations result from among-individual differences in telomere length determined genetically or by early-life envi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93da3eff7fc3ea28ab060f0b0fca9553
https://hdl.handle.net/11250/3052487
https://hdl.handle.net/11250/3052487
Autor:
S. Ross, Ross Carruthers, Robert J. Mairs, W. Nicol Keith, Michael R. Zalutsky, Gamal Akabani, J Owens, Ganesan Vaidyanathan, Marie Boyd, Jennifer Dorrens, Philip Welsh
Publikováno v:
The Journal of Gene Medicine. 6:937-947
Background Targeted radiotherapy achieves malignant cell-specific concentration of radiation dosage by tumour-affinic molecules conjugated to radioactive atoms. Combining gene therapy with targeted radiotherapy is attractive because the associated cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e2ac420b1d7978a88789679875cfb8
https://doi.org/10.1002/jgm.578
https://doi.org/10.1002/jgm.578
Autor:
Marie, Boyd, Susan C, Ross, Jennifer, Dorrens, Natasha E, Fullerton, Ker Wei, Tan, Michael R, Zalutsky, Robert J, Mairs
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 47(6)
Recent studies have shown that indirect effects of ionizing radiation may contribute significantly to the effectiveness of radiotherapy by sterilizing malignant cells that are not directly hit by the radiation. However, there have been few investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24116cb6f707b5816c0e660efdd07591
https://pubmed.ncbi.nlm.nih.gov/16741295
https://pubmed.ncbi.nlm.nih.gov/16741295