Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jennifer D. Stone"'
Autor:
Jennifer D. Stone, David eKranz
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Over the last several years, there has been considerable progress in the treatment of cancer using gene modified adoptive T cell therapies. Two approaches have been used, one involving the introduction of a conventional alpha-beta T cell receptor (TC
Externí odkaz:
https://doaj.org/article/a9867fc89c004777b39d0acc1ef72e19
Despite progress in adoptive T-cell therapies, the identification of targets remains a challenge. Although chimeric antigen receptors recognize cell-surface antigens, T-cell receptors (TCR) have the advantage that they can target the array of intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d017c946731750f4b19a48cc234e1b85
https://doi.org/10.1158/2326-6066.c.6549883.v1
https://doi.org/10.1158/2326-6066.c.6549883.v1
Supplementary Table S1: Predicted HLA-A2 binding MART-1 homologues present in human and mouse proteomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6dd3c869840be7a972c69bbc18bfc8
https://doi.org/10.1158/2326-6066.22542340.v1
https://doi.org/10.1158/2326-6066.22542340.v1
Supplementary Figure S3: Reactivity of T1 or RD1 TCR transduced CD8+ T cells with human peptides containing central "GIG" motif.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ac734149c209a075ab5c2180b17f81
https://doi.org/10.1158/2326-6066.22542343.v1
https://doi.org/10.1158/2326-6066.22542343.v1
Publikováno v:
Cancer Immunology Research. 7:2025-2035
Despite progress in adoptive T-cell therapies, the identification of targets remains a challenge. Although chimeric antigen receptors recognize cell-surface antigens, T-cell receptors (TCR) have the advantage that they can target the array of intrace
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135986 (2015)
Staphylococcal and streptococcal exotoxins, also known as superantigens, mediate a range of diseases including toxic shock syndrome, and they exacerbate skin, pulmonary and systemic infections caused by these organisms. When present in food sources t
Externí odkaz:
https://doaj.org/article/7974c13103904e4580affe1d8f80aa58
Autor:
Brendan K. Reed, Andrew J. Bordner, David M. Kranz, Michael A. Barry, Kalli R. Henning, Diana Gil, Adam G. Schrum, Virginia P. Van Keulen, Michael J. Hansen, Kevin D. Pavelko, Larry R. Pease, Christopher A. Parks, Jennifer D. Stone
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(8)
Successful efforts to activate T cells capable of recognizing weak cancer-associated self-antigens have employed altered peptide antigens to activate T cell responses capable of cross-reacting on native tumor-associated self. A limitation of this app
Publikováno v:
Cancer Immunol Res
Despite progress in adoptive T-cell therapies, identification of targets remains a challenge. Although chimeric antigen receptors recognize cell-surface antigens, T-cell receptors (TCRs) have the advantage that they can target the array of intracellu
Autor:
Kathleen M. Haines, Alexandria P. Cogdill, Decheng Song, Laura A. Johnson, John Scholler, Carl H. June, Regina M. Young, Boris Engels, Avery D. Posey, Michael Feldman, Taylor J. Chen, Catharina Steentoft, David M. Kranz, Thomas Daugbjerg Madsen, Robert D. Schwab, Ulla Mandel, Hans Schreiber, Henrik Clausen, Karin Schreiber, Brian Keith, Alina C. Boesteanu, Jennifer D. Stone
Publikováno v:
Immunity. 44:1444-1454
Genetically modified T cells expressing chimeric antigen receptors (CARs) demonstrate robust responses against lineage restricted, non-essential targets in hematologic cancers. However, in solid tumors, the full potential of CAR T cell therapy is lim
Autor:
Hattie Xu, Sean Durning, Noah Pefaur, Yoshiko Akamatsu, Andrew Urick, Fiona A. Harding, Jennifer D. Stone, Kamel Izeradjene, Adam S. Chervin, John Harlan, Ningyan Wang, Enrico L. Digiammarino, Travis Durkin
Publikováno v:
The FASEB Journal. 34:1-1