Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jennifer D. Ly-Huynh"'
Autor:
Simone Avanzi, Jennifer D. Ly-Huynh, Daria Camozzi, Gualtiero Alvisi, Valerio Leoni, Alessandro Ripalti, Daniele Musiani
Publikováno v:
Biochemistry. 47:13764-13777
The polymerase accessory protein of the human herpes simplex virus type 1 (HSV-1) DNA polymerase UL42 plays an essential role in viral replication, conferring processivity to the catalytic subunit UL30. We show here that UL42 is imported to the nucle
Autor:
Kim G. Lieu, Penelope Alexandra Falshaw Whiley, David A. Jans, Jennifer D. Ly-Huynh, Andrew T. Major, Janet E. Holt, Kate L Loveland
Publikováno v:
Biology of Reproduction. 85:1191-1202
Spermatogenesis, the process of generating haploid sperm capable of fertilizing the female gamete, requires the timely transport into the nucleus of transcription and chromatin-remodeling factors, mediated by members of the importin (IMP) superfamily
Autor:
Donna Jo Merriner, Deborah M. Bianco, Moira K O'Bryan, Stephanie Jay Smith, Gerard M. Gibbs, Jennifer D Ly-Huynh, Birunthi Niranjan, Amy Herlihy, Duangporn Jamsai
Publikováno v:
REPRODUCTION. 135:751-759
Cysteine-rich secretory protein 2 (CRISP2) is a testis-enriched protein localized to the sperm acrosome and tail. CRISP2 has been proposed to play a critical role in spermatogenesis and male fertility, although the precise function(s) of CRISP2 remai
Autor:
David A. Jans, A. Efthymiadis, Gary R. Hime, Janet E. Holt, Kate L Loveland, Jennifer D. Ly-Huynh
Publikováno v:
Current Genomics. 8:323-334
Access to nuclear genes in eukaryotes is provided by members of the importin (IMP) superfamily of proteins, which are of alpha- or beta-types, the best understood nuclear import pathway being mediated by a heterodimer of an IMP alpha and IMP beta1. I
Publikováno v:
Biochemical and biophysical research communications. 450(1)
We previously showed that increased intracellular calcium can modulate Importin (Imp)β1-dependent nuclear import of SRY-related chromatin remodeling proteins. Here we extend this work to show for the first time that high intracellular calcium inhibi
Autor:
Rebecca G. Davies, Gurpreet Kaur, Katarzyna Gajewska, Anette Szczepny, Manisha M Dias, Kate L Loveland, Chunxiao Wang, Kylie M. Wagstaff, Jennifer D. Ly-Huynh, David A. Jans
Publikováno v:
The Biochemical journal. 461(3)
A key factor in oncogenesis is the transport into the nucleus of oncogenic signalling molecules, such as Gli1 (glioma-associated oncogene homologue 1), the central transcriptional activator in the Hedgehog signalling pathway. Little is known, however
Autor:
Jennifer D. Ly-Huynh, Yoshihiro Yoneda, David A. Jans, Kate L Loveland, Peter Koopman, Julia Young, Cate Browne, Yoichi Miyamoto, Helen E Lescesen
Publikováno v:
Biochimica et biophysica acta. 1833(10)
The importin (IMP) superfamily of nuclear transport proteins is essential to key developmental pathways, including in the murine testis where expression of the 6 distinct IMPα proteins is highly dynamic. Present predominantly from the spermatocyte s
Autor:
Jennifer D, Ly-Huynh, Kim G, Lieu, Andrew T, Major, Penelope A F, Whiley, Janet E, Holt, Kate L, Loveland, David A, Jans
Publikováno v:
Biology of reproduction. 85(6)
Spermatogenesis, the process of generating haploid sperm capable of fertilizing the female gamete, requires the timely transport into the nucleus of transcription and chromatin-remodeling factors, mediated by members of the importin (IMP) superfamily
Autor:
E. Richards, Helen E Lescesen, A. Efthymiadis, G. A. Matera, I. Meier, Jennifer D. Ly-Huynh, Penny A. F. Whiley, Kate L Loveland, David A. Jans
Publikováno v:
Reproduction, Fertility and Development. 22:11
Spermatogenesis, the progressive maturation of immature germ cells to form spermatozoa, requires nucleocytoplasmic shuttling of nuclear factors to implement changes in gene transcription, as well as the storage and alternative splicing of mRNA transc
Publikováno v:
Reproduction, Fertility and Development. 20:50
Spermatogenesis, the morphogenetic process of generating haploid sperm capable of fertilising the female gamete, requires transport into the nucleus of transcription and chromatin remodelling factors to implement genome compaction. This transport is