Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer D. Kubic"'
Publikováno v:
Oncology Letters
Pancreatic cancer is a lethal disease with a propensity for invading and metastasizing into the surrounding tissues, including the liver and intestines. A number of factors are aberrantly overexpressed in this tumor type and actively promote cancer p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efa14033c1785bd94c45ef37d03a8db
http://europepmc.org/articles/PMC5452919
http://europepmc.org/articles/PMC5452919
Publikováno v:
Journal of Cellular Biochemistry. 117:533-541
Several key transcription factors regulate cell growth, survival, and differentiation during neural crest and melanoblast development in the embryo, and these same pathways may be reactivated in tumors arising from the progenitors of these cells. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fbc7fb64f574c7d7020a1ff30026535
https://doi.org/10.1002/jcb.25306
https://doi.org/10.1002/jcb.25306
Publikováno v:
Molecular Cancer Research. 10:1065-1076
GSK-3 is a serine/threonine kinase involved in a diverse range of cellular processes. GSK-3 exists in two isoforms, GSK-3α and GSK-3β, which possess some functional redundancy but also play distinct roles depending on developmental and cellular con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ad1a32137bc6286b411f0941380d475
https://doi.org/10.1158/1541-7786.mcr-11-0387
https://doi.org/10.1158/1541-7786.mcr-11-0387
Autor:
Elizabeth C. Little, Sasank Konda, Andrew E. Aplin, Jason W. Lui, Ravi Salgia, Anton E. Ludvik, Deborah Lang, Jennifer D. Kubic
Publikováno v:
The Journal of biological chemistry. 290(36)
Metastatic melanoma is an aggressive and deadly disease. The chemokine receptor CXCR4 is active in melanoma metastasis, although the mechanism for the promotion and maintenance of CXCR4 expression in these cells is mostly unknown. Here, we find melan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19abe5eea68cde8c17b5992d6fcfd615
https://pubmed.ncbi.nlm.nih.gov/26205821
https://pubmed.ncbi.nlm.nih.gov/26205821
Publikováno v:
Oncogene
Melanoma is a highly aggressive disease that is difficult to treat owing to rapid tumor growth, apoptotic resistance and high metastatic potential. The MET proto-oncogene (MET) tyrosine kinase receptor promotes many of these cellular processes, but w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15babf8b9ed7493db1a0ea5fc566bdb9
https://pubmed.ncbi.nlm.nih.gov/25531327
https://pubmed.ncbi.nlm.nih.gov/25531327
Publikováno v:
Pigment cellmelanoma research. 21(6)
Transcription factors initiate a program of gene expression and are catalysts in downstream molecular cascades that modulate a variety of cellular processes. Pax3 is a transcription factor that is important in the melanocyte and influences melanocyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96dce32953f3a48e38d421d1d02ef4ee
https://pubmed.ncbi.nlm.nih.gov/18983540
https://pubmed.ncbi.nlm.nih.gov/18983540