Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jennifer D. Bright"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 6 (2022)
Cancer immunotherapy is a powerful tool for inducing antigen-specific antitumor cytotoxic T lymphocytes (CTLs). Next-generation strategies may include vaccination against overexpressed oncogenic tumor-self antigens. Previously, we reported vaccinatio
Externí odkaz:
https://doaj.org/article/e7a79d26094148eead68089850eccb11
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 6, Pp 1413-1423 (2020)
Development of cancer vaccines targeting tumor self-antigens is complex and challenging due to the difficulty of overcoming immune tolerance to self-proteins. Vaccination against tumor self-protein D52 (D52) has been successful, although complete pro
Externí odkaz:
https://doaj.org/article/6227b90d0a4b424cb2ae56a691ac0db6
Publikováno v:
Hum Vaccin Immunother
Development of cancer vaccines targeting tumor self-antigens is complex and challenging due to the difficulty of overcoming immune tolerance to self-proteins. Vaccination against tumor self-protein D52 (D52) has been successful, although complete pro
Publikováno v:
Human Vaccines & Immunotherapeutics. 10:3297-3305
Overexpressed tumor-self antigens represent the largest group of candidate vaccine targets. Those exhibiting a role in oncogenesis may be some of the least studied but perhaps most promising. This review considers this subset of self antigens by high
Publikováno v:
Oncoimmunology
Tumor protein D52 (D52) is constitutively expressed in healthy tissues and overexpressed in multiple cancers, including (but not limited to) breast, prostate and ovarian carcinomas. Although the normal functions of D52 are unknown, it is clear that i
Publikováno v:
Cancer Research. 70:4791-4791
Tumor protein D52 (TPD52) is a novel auto-antigen involved in cellular transformation, proliferation and metastasis. Its over-expression has been demonstrated in several human malignancies including prostate, breast, and ovarian carcinomas. Murine TP