Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jennifer D Wuerth"'
Autor:
Damien Bertheloot, Carlos WS Wanderley, Ayda H Schneider, Lisa DJ Schiffelers, Jennifer D Wuerth, Jan MP Tödtmann, Salie Maasewerd, Ibrahim Hawwari, Fraser Duthie, Cornelia Rohland, Lucas S Ribeiro, Lea‐Marie Jenster, Nathalia Rosero, Yonas M Tesfamariam, Fernando Q Cunha, Florian I Schmidt, Bernardo S Franklin
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 6, Pp 1-19 (2022)
Abstract Inflammasomes sense intracellular clues of infection, damage, or metabolic imbalances. Activated inflammasome sensors polymerize the adaptor ASC into micron‐sized “specks” to maximize caspase‐1 activation and the maturation of IL‐1
Externí odkaz:
https://doaj.org/article/c80e9b1804f64a2f89cb019c3eee47e4
Autor:
Lea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, Anja vom Hemdt, Jennifer D. Wuerth, Lisa D.J. Schiffelers, Yonas M. Tesfamariam, Florian N. Gohr, Laura Klein, Ines H. Kaltheuner, Stefan Ebner, Dorothee J. Lapp, Jacob Mayer, Jonas Moecking, Hidde L. Ploegh, Eicke Latz, Felix Meissner, Matthias Geyer, Beate M. Kümmerer, Florian I. Schmidt
Publikováno v:
Journal of Experimental Medicine. 220
Inflammasomes integrate cytosolic evidence of infection or damage to mount inflammatory responses. The inflammasome sensor NLRP1 is expressed in human keratinocytes and coordinates inflammation in the skin. We found that diverse stress signals induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b268466639bc0c9a69a6f4e077cca158
https://doi.org/10.1084/jem.20220837
https://doi.org/10.1084/jem.20220837
Autor:
Jennifer D, Wuerth, Friedemann, Weber
Publikováno v:
Current Opinion in Immunology. 78:102251
The interferon-regulated kinase PKR (protein kinase RNA-activated) is a potent innate immune factor against a broad range of viruses. Being part of the integrated stress response (ISR), its restrictive effect is predominantly exerted by phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f568408a82f724715ae6bfe5e6bb733
https://doi.org/10.1016/j.coi.2022.102251
https://doi.org/10.1016/j.coi.2022.102251