Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jennifer D Cohen"'
Autor:
Susanna K Birnbaum, Jennifer D Cohen, Alexandra Belfi, John I Murray, Jennifer R G Adams, Andrew D Chisholm, Meera V Sundaram
Publikováno v:
PLoS Genetics, Vol 19, Iss 9, p e1010944 (2023)
Some types of collagens, including transmembrane MACIT collagens and C. elegans cuticle collagens, are N-terminally cleaved at a dibasic site that resembles the consensus for furin or other proprotein convertases of the subtilisin/kexin (PCSK) family
Externí odkaz:
https://doaj.org/article/53857858b697489fbc22d3ff6c2c5536
Autor:
Sophie S Katz, Trevor J Barker, Hannah M Maul-Newby, Alessandro P Sparacio, Ken C Q Nguyen, Chloe L Maybrun, Alexandra Belfi, Jennifer D Cohen, David H Hall, Meera V Sundaram, Alison R Frand
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010348 (2022)
Epithelial cells secrete apical extracellular matrices to form protruding structures such as denticles, ridges, scales, or teeth. The mechanisms that shape these structures remain poorly understood. Here, we show how the actin cytoskeleton and a prov
Externí odkaz:
https://doaj.org/article/a013b578641448c7af122004be999db9
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009188 (2020)
Zona Pellucida domain (ZP) proteins are critical components of the body's external-most protective layers, apical extracellular matrices (aECMs). Although their loss or dysfunction is associated with many diseases, it remains unclear how ZP proteins
Externí odkaz:
https://doaj.org/article/1950fcd9d50c4d43ad30c145f119fa66
Autor:
Jennifer D Cohen, Alessandro P Sparacio, Alexandra C Belfi, Rachel Forman-Rubinsky, David H Hall, Hannah Maul-Newby, Alison R Frand, Meera V Sundaram
Publikováno v:
eLife, Vol 9 (2020)
Biological tubes must develop and maintain their proper diameter to transport materials efficiently. These tubes are molded and protected in part by apical extracellular matrices (aECMs) that line their lumens. Despite their importance, aECMs are dif
Externí odkaz:
https://doaj.org/article/bbbb0234decf4fcdb711243e8c2ba8e9
Autor:
Hasreet K Gill, Jennifer D Cohen, Jesus Ayala-Figueroa, Rachel Forman-Rubinsky, Corey Poggioli, Kevin Bickard, Jean M Parry, Pu Pu, David H Hall, Meera V Sundaram
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006205 (2016)
Most epithelial cells secrete a glycoprotein-rich apical extracellular matrix that can have diverse but still poorly understood roles in development and physiology. Zona Pellucida (ZP) domain glycoproteins are common constituents of these matrices, a
Externí odkaz:
https://doaj.org/article/ff4960e0f98f46948a38f240a9188455
Publikováno v:
Computational Toxicology. 26:100273
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65e4a28de02fa7195129fc33258c233e
https://doi.org/10.1016/j.comtox.2023.100273
https://doi.org/10.1016/j.comtox.2023.100273
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 186(2)
Elucidation of predictive fluidic biochemical markers to detect and monitor chemical-induced neurodegeneration has been a major challenge due to a lack of understanding of molecular mechanisms driving altered neuronal morphology and function, as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb0af7f18d03728163e40e6d95d7faf
https://pubmed.ncbi.nlm.nih.gov/35134991
https://pubmed.ncbi.nlm.nih.gov/35134991
Autor:
Qin, Wang, Jennifer D, Cohen, Tomoya, Yukawa, Heather, Estrella, Chris, Leonard, Jairo, Nunes, Colin, Choi, Lauren, Lewis, Kevin S, Baker, Kazuhiro, Kuga, Yvonne P, Dragan, Matthew P, Wagoner, Nibha, Mishra
Publikováno v:
ALTEX.
Drug-induced neurotoxicity is a leading cause of safety-related attrition for therapeutics in clinical trials, often driven by poor predictivity of preclinical in vitro and in vivo models of neurotoxicity. Over a dozen different iPSC-derived 3D spher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865e4114ccce070bc00eddc20bf043cd
https://doi.org/10.14573/altex.2112221
https://doi.org/10.14573/altex.2112221
Autor:
Sophie S. Katz, Trevor J. Barker, Hannah M. Maul-Newby, Alessandro P. Sparacio, Ken C.Q. Nguyen, Chloe L. Maybrun, Alexandra Belfi, Jennifer D. Cohen, David H. Hall, Meera V. Sundaram, Alison R. Frand
SUMMARYApical extracellular matrices can form protruding structures such as denticles, ridges, scales, or teeth on the surfaces of epithelia. The mechanisms that shape these structures remain poorly understood. Here, we show how the actin cytoskeleto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ae958a65ba58d7f8353ca329547297
https://doi.org/10.1101/2021.12.28.474392
https://doi.org/10.1101/2021.12.28.474392
Autor:
Anne Spang, Nicholas D Serra, Meera V. Sundaram, Andres Kaech, Carla Elizabeth Cadena del Castillo, Jennifer D. Cohen
Publikováno v:
Genetics
The Patched-related superfamily of transmembrane proteins can transport lipids or other hydrophobic molecules across cell membranes. While the Hedgehog receptor Patched has been intensively studied, much less is known about the biological roles of ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12b4e490ba1b2b7e8b8d446aae8636b
https://doi.org/10.1093/genetics/iyab132
https://doi.org/10.1093/genetics/iyab132