Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jennifer Chickering"'
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Ian De Boer, Jennifer Chickering, Albert T. Profy, George T. Milne, Mark Currie, John P. Hanrahan, Michael Cressman, George Bakris, James D. Wakefield, Phebe Wilson, Jelena P. Seferovic
Publikováno v:
Diabetes. 69
Background: Impaired nitric oxide (NO) signaling has been implicated in the progression of diabetic kidney disease (DKD). Praliciguat (PRL) is a soluble guanylate cyclase stimulator that augments NO signaling in vitro and reduces proteinuria and fast
Autor:
Albert T. Profy, John P. Hanrahan, Michael Hall, Linda Morrow, Jennifer Chickering, G. Todd Milne, Mark Currie, Paul Miller, James D. Wakefield, Phebe J. Wilson
Publikováno v:
Diabetes. 67
Background: Praliciguat (IW-1973), a soluble guanylate cyclase stimulator, has been shown to augment nitric oxide (NO) signaling and reduce fasting plasma glucose and proteinuria in an animal model of diabetic nephropathy. In healthy adults, repeated
Autor:
John Hanrahan, James Wakefield, Phebe Wilson, Marina Mihova, Jennifer Chickering, Dennis Ruff, Michael Hall, Todd Milne, Mark Currie, Albert Profy
Publikováno v:
Hypertension. 70
Background: Soluble guanylate cyclase (sGC), an enzyme that catalyzes the formation of cyclic guanosine monophosphate (cGMP) in response to nitric oxide (NO) binding, is a key mediator of local blood flow, inflammation, and fibrosis. IW-1973 is an or