Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jennifer Chiang"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 4, Pp 1251-1257 (2017)
Drug resistance is a consequence of how most modern medicines work. Drugs exert pressure on cells that causes death or the evolution of resistance. Indeed, highly specific drugs are rendered ineffective by a single DNA mutation. In this study, we app
Externí odkaz:
https://doaj.org/article/bcd061e535204c07982c95dd194d82e8
Autor:
Erica Acton, Amy Huei-Yi Lee, Pei Jun Zhao, Stephane Flibotte, Mauricio Neira, Sunita Sinha, Jennifer Chiang, Patrick Flaherty, Corey Nislow, Guri Giaever
Publikováno v:
Open Biology, Vol 7, Iss 6 (2017)
The Yeast Knockout (YKO) collection has provided a wealth of functional annotations from genome-wide screens. An unintended consequence is that 76% of gene annotations derive from one genotype. The nutritional auxotrophies in the YKO, in particular,
Externí odkaz:
https://doaj.org/article/e9d165af489c4e93b631e666f28c5da8
Autor:
Mark D Mathew, Neal D Mathew, Angela Miller, Mike Simpson, Vinci Au, Stephanie Garland, Marie Gestin, Mark L Edgley, Stephane Flibotte, Aruna Balgi, Jennifer Chiang, Guri Giaever, Pamela Dean, Audrey Tung, Michel Roberge, Calvin Roskelley, Tom Forge, Corey Nislow, Donald Moerman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005058 (2016)
The lack of new anthelmintic agents is of growing concern because it affects human health and our food supply, as both livestock and plants are affected. Two principal factors contribute to this problem. First, nematode resistance to anthelmintic dru
Externí odkaz:
https://doaj.org/article/bf918819764c48fb8380f8fa310027ae
Autor:
Jennifer Chiang, 蔣世平
98
Taking the mutual fund investors in Taiwan as the research object, this study intends to investigates the determinants of the investment behavior and investment performance. Based on existing literature, this study identifies three questions
Taking the mutual fund investors in Taiwan as the research object, this study intends to investigates the determinants of the investment behavior and investment performance. Based on existing literature, this study identifies three questions
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/18841683399227400977
Autor:
Jennifer Chiang, Timothy G. Hammond, Holly H. Birdsall, Margaret A. Gunter, Corey Nislow, Guri Giaever, Patricia L. Allen
Publikováno v:
Microgravity Science and Technology
Baker’s yeast (Saccharomyces cerevisiae) has broad genetic homology to human cells. Although typically grown as 1-2mm diameter colonies under certain conditions yeast can form very large (10 + mm in diameter) or ‘giant’ colonies on agar. Giant
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 4, Pp 1251-1257 (2017)
Drug resistance is a consequence of how most modern medicines work. Drugs exert pressure on cells that causes death or the evolution of resistance. Indeed, highly specific drugs are rendered ineffective by a single DNA mutation. In this study, we app
Autor:
Corey Nislow, Jaeyul Cha, Jennifer Chiang, Jae-Seoun Hur, Grant Tran, Youngho Kwon, Guri Giaever, Youn-Sig Kwak
Publikováno v:
Journal of Applied Microbiology. 121:1580-1591
Aim To determine uncovered antifungal activity of lichen derived compound; vulpinic acid by using chemical-genetic analyses. Methods and Results Haploinsufficiency and homozygous profiling assays was performed, revealing that strains lacking GLC7, ME
Autor:
Sunita Sinha, Peter C. Stirling, Megan Kofoed, Karissa L. Milbury, Corey Nislow, Shay Ben-Aroya, Philip Hieter, Jennifer Chiang, Guri Giaever
Publikováno v:
G3: Genes|Genomes|Genetics
Systematic analyses of essential gene function using mutant collections in Saccharomyces cerevisiae have been conducted using collections of heterozygous diploids, promoter shut-off alleles, through alleles with destabilized mRNA, destabilized protei
Autor:
Megan Kofoed, Christelle Keong, Guri Giaever, Philip Hieter, Akil Hamza, Corey Nislow, Erik Tammpere, Jennifer Chiang
Publikováno v:
Genetics
While the pace of discovery of human genetic variants in tumors, patients, and diverse populations has rapidly accelerated, deciphering their functional consequence has become rate-limiting. Using cross-species complementation, model organisms like t
Autor:
Stephane Flibotte, Jennifer Chiang, Guri Giaever, Patrick Flaherty, Mauricio Neira, Pei Jun Zhao, Amy S. Lee, Erica Acton, Corey Nislow, Sunita Sinha
Publikováno v:
Open Biology
Open Biology, Vol 7, Iss 6 (2017)
Open Biology, Vol 7, Iss 6 (2017)
The Yeast Knockout (YKO) collection has provided a wealth of functional annotations from genome-wide screens. An unintended consequence is that 76% of gene annotations derive from one genotype. The nutritional auxotrophies in the YKO, in particular,