Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jennifer Caplain"'
Autor:
Jennifer Caplain, Madhumita Das, Elizabeth Grimm, Shrikar Rajagopal, Oksana B. Serebrennikova, Robert E. Martell, Philip N. Tsichlis, Mohammad Wasif Saif
Publikováno v:
Cancer Chemotherapy and Pharmacology. 84:1323-1331
Metformin activates AMP-related pathways leading to inactivation of mammalian target of rapamycin (mTOR) and suppression of its downstream effectors, crucial for cancer growth. Epidemiologic studies showed a reduced incidence and improved survival in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e13fde73c4c55b84c76435dfef058c
https://doi.org/10.1007/s00280-019-03967-3
https://doi.org/10.1007/s00280-019-03967-3
Autor:
Shrikar Rajagopal, Martin D. Goodman, Jennifer Caplain, Nicholas C. DeVito, Bruce A. Orkin, Philip N. Tsichlis, Robert E. Martell, Elizabeth Grimm, Wasif M. Saif, Daniel Popowich
Publikováno v:
Journal of Clinical Oncology. 32:e14581-e14581
e14581 Background: The cancer stem cell (CSC) hypothesis of tumorigenesis suggests that unlike most cancer cells within a tumor CSC resist chemotherapy and can regenerate various cell types in tumo...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c5a96d82c0a78ac38bd33c1dac6e6c4
https://doi.org/10.1200/jco.2014.32.15_suppl.e14581
https://doi.org/10.1200/jco.2014.32.15_suppl.e14581
Autor:
Wasif M. Saif, Athena Kritharis, Shrikar Rajagopal, Philip N. Tsichlis, Elizabeth Grimm, Jennifer Caplain, Robert E. Martell
Publikováno v:
Journal of Clinical Oncology. 32:2560-2560
2560 Background: Metformin has recently received increased attention because of its potential antitumorigenic effects on a number of cancers. It activates AMP-related pathways leading to inactivati...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::127910a84fd0dbcc99d750c84f70c924
https://doi.org/10.1200/jco.2014.32.15_suppl.2560
https://doi.org/10.1200/jco.2014.32.15_suppl.2560