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pro vyhledávání: '"Jennifer C. Mutrie"'
Publikováno v:
Journal of Cell Communication and Signaling. 5:111-122
Osteopontin (OPN) is a matricellular protein that binds to a number of cell surface receptors including integrins and CD44. It is expressed in many tissues and secreted into body fluids including blood, milk and urine. OPN plays important physiologic
Publikováno v:
Journal of Cellular and Molecular Medicine
Osteopontin (OPN) is a secreted protein present in bodily fluids and tissues. It is subject to multiple post-translational modifications, including phosphorylation, glycosylation, proteolytic cleavage and crosslinking by transglutamination. Binding o
Publikováno v:
Cancer biologytherapy. 12(8)
Src kinase and Hsp90 play important roles in malignancy-promoting signaling pathways in a variety of cancers and related targeting agents are presently in clinical trials. To help improve the success of Src kinase and Hsp90 inhibitor therapies, ident