Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jennifer C Moore"'
Autor:
Martin Sauvageau, Loyal A Goff, Simona Lodato, Boyan Bonev, Abigail F Groff, Chiara Gerhardinger, Diana B Sanchez-Gomez, Ezgi Hacisuleyman, Eric Li, Matthew Spence, Stephen C Liapis, William Mallard, Michael Morse, Mavis R Swerdel, Michael F D’Ecclessis, Jennifer C Moore, Venus Lai, Guochun Gong, George D Yancopoulos, David Frendewey, Manolis Kellis, Ronald P Hart, David M Valenzuela, Paola Arlotta, John L Rinn
Publikováno v:
eLife, Vol 2 (2013)
Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in animal models. To investigate the functional relevance of lncRNAs in various physiological cond
Externí odkaz:
https://doaj.org/article/5fdb35f4c02f45c69bc508db25a26cb3
Autor:
Loyal A Goff, Jonathan Davila, Mavis R Swerdel, Jennifer C Moore, Rick I Cohen, Hao Wu, Yi E Sun, Ronald P Hart
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7192 (2009)
BACKGROUND:MicroRNAs are required for maintenance of pluripotency as well as differentiation, but since more microRNAs have been computationally predicted in genome than have been found, there are likely to be undiscovered microRNAs expressed early i
Externí odkaz:
https://doaj.org/article/59811a69d7fc4678a7a084bff70e68e4
Autor:
Philip Dexheimer, Jeffrey L. Dage, Xianglong Zhang, Thomas J. Ward, Yu-Wen Alvin Huang, Yingfei Liu, Marius Wernig, Zhiping P. Pang, Tamas Danko, ChangHui Pak, Jinzhao Wang, Vincent R. Mirabella, Kang Jin, Michael McLachlan, Madhuri Vangipuram, Carolin Purmann, Jennifer C. Moore, Junyi Ma, Bradley J. Swanson, Sarah Grieder, Eric E. Bardes, Douglas F. Levinson, Alexis Mitelpunkt, Bruce J. Aronow, Alexander E. Urban, Thomas C. Südhof, Pingping Qu
Publikováno v:
Proc Natl Acad Sci U S A
Heterozygous NRXN1 deletions constitute the most prevalent currently known single-gene mutation predisposing to schizophrenia. Previous studies showed that engineered heterozygous NRXN1 deletions impaired neurotransmitter release in human neurons, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4862173dfbc4ea72fe8169d61db3d2ea
https://doi.org/10.1073/pnas.2025598118
https://doi.org/10.1073/pnas.2025598118
Publikováno v:
Stem Cell Research, Vol 47, Iss, Pp 101926-(2020)
We have generated two iPSC lines from skin biopsies of two healthy individuals. Skin fibroblasts were derived and reprogrammed using a Sendai virus-based approach. The resulting iPSC lines have normal karyotype, express stemness markers and can gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32498ead332b22dc1268be05c715788b
https://pubmed.ncbi.nlm.nih.gov/32738631
https://pubmed.ncbi.nlm.nih.gov/32738631
Autor:
Roy V. Sillitoe, Anna Taylor, Jerrold L. Vitek, Mark Hallett, Kristina Simonyan, Sarah Pirio Richardson, Laurie J. Ozelius, Nutan Sharma, Beth Anne Sieber, Laura B. Scheinfeldt, Codrin Lungu, David G. Standaert, Brian Berman, Philip A. Starr, Christine Swanson-Fisher, Rachel Saunders-Pullman, Jennifer C. Moore, Nicole Calakos, Joel S. Perlmutter
Publikováno v:
Neurology
ObjectiveDystonia is a complex movement disorder. Research progress has been difficult, particularly in developing widely effective therapies. This is a review of the current state of knowledge, research gaps, and proposed research priorities.Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db967d7e5f22873a442e1d3409ddfd7
https://europepmc.org/articles/PMC7274927/
https://europepmc.org/articles/PMC7274927/
Autor:
Mavis R. Swerdel, Zhiping P. Pang, Jay A. Tischfield, Matthew S. Scarnati, Jennifer C. Moore, Ronald P. Hart, Apoorva Halikere, Aula Hamod, Dina Popova
Publikováno v:
Molecular psychiatry
The OPRM1 A118G single nucleotide polymorphism (SNP rs1799971) gene variant encoding the N40D µ-opioid receptor (MOR) has been associated with dependence on opiates and other drugs of abuse but its mechanism is unknown. The frequency of G-allele car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb3f90ea489231ea947b25c22c0f9fa
https://pubmed.ncbi.nlm.nih.gov/31481756
https://pubmed.ncbi.nlm.nih.gov/31481756
Autor:
Atul K. Bhattiprolu, Linda M. Brzustowicz, Christen Crosta, Allen Y. Fu, Stephen G. Clarke, Kristina Hernandez, Kenneth G Paradiso, Bonnie L. Firestein, Natasha R. Dudzinski, Jennifer C. Moore
Publikováno v:
Mol Cell Neurosci
Abnormal dendritic arbor development has been implicated in a number of neurodevelopmental disorders, such as autism and Rett syndrome, and the neuropsychiatric disorder schizophrenia. Postmortem brain samples from subjects with schizophrenia show el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de695feffc6c10e1512836317ee8a12
https://doi.org/10.1016/j.mcn.2020.103562
https://doi.org/10.1016/j.mcn.2020.103562
Autor:
Joachim Kohn, Ronald P. Hart, Kenneth G Paradiso, Prabhas V. Moghe, Neal K. Bennett, Marius Wernig, Zhiping P. Pang, Jennifer C. Moore, Stephen G. Clarke, Nicola L. Francis, Aaron L. Carlson, Apoorva Halikere
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications
Cell replacement therapy with human pluripotent stem cell-derived neurons has the potential to ameliorate neurodegenerative dysfunction and central nervous system injuries, but reprogrammed neurons are dissociated and spatially disorganized during tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8ae35734b22e38ff780e706b8d7baf
https://doaj.org/article/1cdbd92bc9c24daca3285c1be2d05c12
https://doaj.org/article/1cdbd92bc9c24daca3285c1be2d05c12
Autor:
Michael P. Lazaropoulos, Alana J. Toro-Ramos, Howard M. Lederman, Jianmin Chen, Jennifer C. Moore, Ronald P. Hart, Mavis R. Swerdel, Jennifer M. Wright, Lucy Lin, Gary S. Hoffman
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1097-1108 (2015)
Stem Cell Reports
Stem Cell Reports
Summary A spontaneously reverted iPSC line was identified from an A-T subject with heterozygous ATM truncation mutations. The reverted iPSC line expressed ATM protein and was capable of radiation-induced phosphorylation of CHK2 and H2A.X. Genome-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38e72fa143e337777946e9e018253b8
http://www.sciencedirect.com/science/article/pii/S2213671115003070
http://www.sciencedirect.com/science/article/pii/S2213671115003070
Autor:
Ronald P. Hart, Mavis R. Swerdel, Matthew S. Scarnati, Apoorva Halikere, Jay A. Tischfield, Dina Popova, Zhiping P. Pang, Jennifer C. Moore, Aula Hamod
Publikováno v:
Molecular Psychiatry. 25:1355-1355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2279bf9ffec8cc69d597e9a3477ab4cf
https://doi.org/10.1038/s41380-020-0799-0
https://doi.org/10.1038/s41380-020-0799-0