Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jennifer C Hocking"'
Autor:
Jennifer C Hocking, Jakub K Famulski, Kevin H Yoon, Sonya A Widen, Cassidy S Bernstein, Sophie Koch, Omri Weiss, FORGE Canada Consortium, Seema Agarwala, Adi Inbal, Ordan J Lehmann, Andrew J Waskiewicz
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007246 (2018)
The eye primordium arises as a lateral outgrowth of the forebrain, with a transient fissure on the inferior side of the optic cup providing an entry point for developing blood vessels. Incomplete closure of the inferior ocular fissure results in colo
Externí odkaz:
https://doaj.org/article/3b14a0477b30448087f0d728147cd997
Autor:
Paul W. Chrystal, Nils J. Lambacher, Lance P. Doucette, James Bellingham, Elena R. Schiff, Nicole C. L. Noel, Chunmei Li, Sofia Tsiropoulou, Geoffrey A. Casey, Yi Zhai, Nathan J. Nadolski, Mohammed H. Majumder, Julia Tagoe, Fabiana D’Esposito, Maria Francesca Cordeiro, Susan Downes, Jill Clayton-Smith, Jamie Ellingford, Genomics England Research Consortium, Omar A. Mahroo, Jennifer C. Hocking, Michael E. Cheetham, Andrew R. Webster, Gert Jansen, Oliver E. Blacque, W. Ted Allison, Ping Yee Billie Au, Ian M. MacDonald, Gavin Arno, Michel R. Leroux
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Motile and non-motile cilia have distinct functions and protein complexes associated with them. Here, the authors show the conserved protein CFAP20 is important for both motile and non-motile cilia and is distinct from other ciliopathy-associated dom
Externí odkaz:
https://doaj.org/article/a85ce5f9aafc4ed1a65a7a9f8a648d61
Publikováno v:
Human Pathology: Case Reports, Vol 23, Iss , Pp 200480- (2021)
Gastrocnemius is a superficial calf muscle with two muscular heads that contribute fibres to the Achilles tendon. While gastrocnemius functions during movement of the knee and ankle joints, the muscle is of particular clinical interest as a target fo
Externí odkaz:
https://doaj.org/article/84182d2e4ff04f948bbc51f1513a4e27
Publikováno v:
Journal of Anatomy. 242:327-353
Sensory neurons use specialized apical processes to perceive external stimuli and monitor internal body conditions. The apical apparatus can include cilia, microvilli, or both, and is adapted for the functions of the particular cell type. Photorecept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f49389093a75007da486549aed485b2
https://doi.org/10.1111/joa.13781
https://doi.org/10.1111/joa.13781
Publikováno v:
Documenta Ophthalmologica. 142:99-109
The electroretinogram (ERG) is a powerful approach for investigating visual function in zebrafish ocular disease models. However, complexity, cost, and a literature gap present as significant barriers for the introduction of this technology to new ze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50acfd03814783c68480ca83af6794ee
https://doi.org/10.1007/s10633-020-09783-y
https://doi.org/10.1007/s10633-020-09783-y
Publikováno v:
Progress in Retinal and Eye Research. 91:101096
Photoreceptor dysfunctions and degenerative diseases are significant causes of vision loss in patients, with few effective treatments available. Targeted interventions to prevent or reverse photoreceptor-related vision loss are not possible without a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6faf802e17d21672d72679ac3c74dca4
https://doi.org/10.1016/j.preteyeres.2022.101096
https://doi.org/10.1016/j.preteyeres.2022.101096
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030731182
The tumor microenvironment significantly contributes to tumor initiation, progression, neo-angiogenesis, and metastasis, and a better understanding of the role of the different cellular players would facilitate the development of novel therapeutic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96262f137a892d176ae6b8334f9e0501
https://doi.org/10.1007/978-3-030-73119-9_4
https://doi.org/10.1007/978-3-030-73119-9_4
Publikováno v:
Cells, Vol 9, Iss 2214, p 2214 (2020)
Cells
Volume 9
Issue 10
Cells
Volume 9
Issue 10
Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Pathogenic mutations in RP1L1 lead to photoreceptor degenerations such as occult macular dystrophy and retinitis pigmentosa. RP1L1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a72b9d59dd40a760e5cf63f4335711
https://www.mdpi.com/2073-4409/9/10/2214
https://www.mdpi.com/2073-4409/9/10/2214
Publikováno v:
Cells
Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Pathogenic mutations in RP1L1 lead to photoreceptor degenerations such as occult macular dystrophy and retinitis pigmentosa. RP1L1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4491bc2cb50eca51ca8bd196fef1ef9
https://pubmed.ncbi.nlm.nih.gov/33007938
https://pubmed.ncbi.nlm.nih.gov/33007938
Publikováno v:
Documenta ophthalmologica. Advances in ophthalmology. 142(1)
The electroretinogram (ERG) is a powerful approach for investigating visual function in zebrafish ocular disease models. However, complexity, cost, and a literature gap present as significant barriers for the introduction of this technology to new ze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b67c69b814ff116dc3db6de84f918bf1
https://pubmed.ncbi.nlm.nih.gov/32691203
https://pubmed.ncbi.nlm.nih.gov/32691203