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pro vyhledávání: '"Jennifer Biesterfeldt"'
Autor:
Steven W. Kubalak, Todd D. Camenisch, Mary Lou Augustine, Scott E. Klewer, Tammy Brehm-Gibson, John A. McDonald, Anthony Calabro, Jennifer Biesterfeldt, Andrew P. Spicer
Publikováno v:
The Journal of clinical investigation. 106(3)
We identified hyaluronan synthase-2 (Has2) as a likely source of hyaluronan (HA) during embryonic development, and we used gene targeting to study its function in vivo. Has2(-/-) embryos lack HA, exhibit severe cardiac and vascular abnormalities, and