Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jennifer Baker-Malcolm"'
Autor:
Huawei Qiu, Xiaoying Jin, Debra A. Barngrover, Karen Lee, Laura Geagan, Tim Edmunds, Lorraine Copertino, Laura Andrews, Kate Zhang, Keirsten Seiger, John M. McPherson, Jennifer Baker-Malcolm
Publikováno v:
Glycobiology. 13:305-313
Fabry disease is a lysosomal storage disease arising from deficiency of the enzyme alpha-galactosidase A. Two recombinant protein therapeutics, Fabrazyme (agalsidase beta) and Replagal (agalsidase alfa), have been approved in Europe as enzyme replace
Autor:
Huawei Qiu, Tim Edmunds, Heather Hughes, Scott Estes, Kenneth P. Karey, Cordula Schwarz, Jennifer Baker-Malcolm, Scott M. Van Patten
Publikováno v:
The Journal of biological chemistry. 278(35)
One form of Niemann-Pick disease is caused by a deficiency in the enzymatic activity of acid sphingomyelinase. During efforts to develop an enzyme replacement therapy based on a recombinant form of human acid sphingomyelinase (rhASM), purified prepar