Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer B. Paulson"'
Autor:
Peng Liu, Jennifer B Paulson, Colleen L Forster, Samantha L Shapiro, Karen H Ashe, Kathleen R Zahs
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126317 (2015)
Amyloid plaques composed of β-amyloid (Aβ) protein are a pathological hallmark of Alzheimer's disease. We here report the generation and characterization of a novel transgenic mouse model of Aβ toxicity. The rTg9191 mice harbor a transgene encodin
Externí odkaz:
https://doaj.org/article/d5e49ffb28e44ff3b5acdc4a0130a87f
Autor:
Peng Liu, James P. Cleary, Jennifer B. Paulson, Karen H. Ashe, Gang Chen, Linda Kotilinek, David A. Bennett, Sylvain Lesné, Colleen L. Forster, Kathleen R. Zahs
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c53c2a45971e31ba3a10f67b897e7a
https://doi.org/10.1016/j.jalz.2011.09.067
https://doi.org/10.1016/j.jalz.2011.09.067
Autor:
Martin Ramsden, Karen H. Ashe, Jennifer B. Paulson, Colleen L. Forster, Eileen McGowan, Mathew A. Sherman
Publikováno v:
The American journal of pathology. 173(3)
Transgenic mouse models that independently express mutations in amyloid precursor protein (APP) and tau have proven useful for the study of the neurological consequences of amyloid-beta (Abeta) plaque and neurofibrillary tangle pathologies. Studies u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1352246a9cb554cef525d9f246a0af1
https://pubmed.ncbi.nlm.nih.gov/18669616
https://pubmed.ncbi.nlm.nih.gov/18669616
Autor:
Kathleen R. Zahs, Peng Liu, Jennifer B. Paulson, Samantha L. Shapiro, Colleen L. Forster, Karen H. Ashe
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126317 (2015)
PLoS ONE
PLoS ONE
Amyloid plaques composed of β-amyloid (Aβ) protein are a pathological hallmark of Alzheimer's disease. We here report the generation and characterization of a novel transgenic mouse model of Aβ toxicity. The rTg9191 mice harbor a transgene encodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1ac6305ed41f607bbe394c0f8cfdfb
https://doi.org/10.1371/journal.pone.0126317
https://doi.org/10.1371/journal.pone.0126317
Autor:
Eileen McGowan, Jennifer B. Paulson, Martin Ramsden, Mei Yue, George A. Carlson, Linda Kotilinek, Mike Hutton, Jada Lewis, Karen S. SantaCruz, Colleen L. Forster, Karen H. Ashe, Aaron Guimaraes
Here, we describe the generation of a novel transgenic mouse model of human tauopathy. The rTg(tauP301L)4510 mouse expresses the P301L mutation in tau (4R0N) associated with frontotemporal dementia and parkinsonism linked to chromosome 17. Transgene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccaf907ee099a8d3eed75303c875b4d2
https://europepmc.org/articles/PMC6725849/
https://europepmc.org/articles/PMC6725849/
Autor:
Bradley T. Hyman, Linda Kotilinek, Jennifer B. Paulson, Colleen L. Forster, Jada Lewis, A. Guimaraes, Mike Hutton, Martin Ramsden, Tara L. Spires, Karen H. Ashe, Eileen McGowan, Ami Mariash, Michael DeTure, Michael A. Kuskowski, Martin Ingelsson, Mei Yue, Karen S. SantaCruz, Jennifer D. Orne, Chris Janus
Publikováno v:
Science (New York, N.Y.). 309(5733)
Neurofibrillary tangles (NFTs) are the most common intraneuronal inclusion in the brains of patients with neurodegenerative diseases and have been implicated in mediating neuronal death and cognitive deficits. Here, we found that mice expressing a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340d2b27fc1fbd3b351e5a0b52f87ffa
https://pubmed.ncbi.nlm.nih.gov/16020737
https://pubmed.ncbi.nlm.nih.gov/16020737