Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jennifer B. Palenchar"'
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Autor:
David A. Wah, Jennifer B. Palenchar, Patricia Soteropoulos, Rachel Morales, Anish Das, Vivian Bellofatto, Virginie Aris, David M. Lukac, Mahrukh Banday, Wenzhe Liu
Publikováno v:
Molecular and Biochemical Parasitology. 186:139-142
RNA polymerase II (RNAP-II) synthesizes the m(7)G-capped Spliced Leader (SL) RNA and most protein-coding mRNAs in trypanosomes. RNAP-II recruitment to DNA usually requires a set of transcription factors that make sequence-specific contacts near trans
Autor:
Elzbieta Bojarska, Edward Darzynkiewicz, Vivian Bellofatto, Stephanie Ng, Hiren Banerjee, Jacek Jemielity, Janusz Stepinski, Andrzej Guranowski, Maciej Lukaszewicz, Jennifer B. Palenchar, David A. Wah
Publikováno v:
RNA. 15:1554-1564
A new member of the FHIT protein family, designated HIT-45, has been identified in the African trypanosome Trypanosoma brucei. Recombinant HIT-45 proteins were purified from trypanosomal and bacterial protein expression systems and analyzed for subst
Publikováno v:
Molecular and biochemical parasitology. 184(1)
Understanding how the biological connectivity of genes and gene products affects evolution is an important aspect of understanding evolution. Genes encoding enzymes are frequently used to carry out such analyses. Interestingly, studies have shown tha
Autor:
Allison H. Sing, Kellie Whitecavage Solnoki, Russell Miller, Caitlyn J. Sofa, Jennifer B. Palenchar, Hillary V. Penek, Paulina A. Ogorzalek
Publikováno v:
Molecular and biochemical parasitology. 181(2)
Trypanosoma brucei, the causative agent of African Sleeping sickness, is replete with unique biochemistry, including unusual features of gene transcription. The parasite also contains over 4500 non-annotated genes, representing novel biochemistry yet
Publikováno v:
Molecular and biochemical parasitology. 179(2)
A putative β-hydroxybutyrate dehydrogenase (βHBDH) ortholog was identified in Trypanosoma brucei , the unicellular eukaryotic parasite responsible for causing African Sleeping Sickness. The trypanosome enzyme has greater sequence similarity to bact
Publikováno v:
The FASEB Journal. 25
Autor:
David A. Wah, Douglas V. Laurents, Anish Das, Nalini Kanneganti, B. Syed Ibrahim, Jennifer B. Palenchar, Gabrielle E. Rieckhof, Vivian Bellofatto
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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6 pags, 4 figs
In trypanosomes, the production of mRNA relies on the synthesis of the spliced leader (SL) RNA. Expression of the SL RNA is initiated at the only known RNA polymerase II promoter in these parasites. In the pathogenic trypanosome,
In trypanosomes, the production of mRNA relies on the synthesis of the spliced leader (SL) RNA. Expression of the SL RNA is initiated at the only known RNA polymerase II promoter in these parasites. In the pathogenic trypanosome,
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 442
RNA interference (RNAi) is a cellular mechanism that is often exploited as a technique for quelling the expression of a specific gene. RNAi studies are carried out in vivo, making this a powerful means for the study of protein function in situ Severa