Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jennifer B. Nguyen"'
Autor:
Sophia Liu, Yuetian Yan, Cody M. Secor, Zachary R. Oberholtzer, Donna J. Skow, Mushhood Sheikh, Youmi Moon, Yue Fu, Cristinel Sandu, Shunhai Wang, Ning Li, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTCo-formulation of multiple drug products is an efficient and convenient approach to simultaneously deliver multiple biotherapeutics with the potentially added benefit of a synergistic therapeutic effect. However, co-formulation also increases
Externí odkaz:
https://doaj.org/article/1494bc863c804d3eb9523d2ed2f12fcb
Autor:
Zhijie Wu, Hongxia Wang, Jikang Wu, Yu Huang, Xueqing Zhao, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles, Haibo Qiu, Ning Li
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 223:115147
Therapeutic antibodies are a major class of pharmaceutical drugs used to treat a wide variety of diseases. They have several advantages including the high specificity and binding affinity to their molecular targets, and generally low immunotoxicity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ce0ee8f42d9e9bf330a7323651028e
https://doi.org/10.1016/j.jpba.2022.115147
https://doi.org/10.1016/j.jpba.2022.115147
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Most organisms rely on innate immune receptors to recognize conserved molecular structures from invading microbes. Two essential innate immune receptors, RIG-I and MDA5, detect viral double-stranded RNA in the cytoplasm. The inflammatory response tri
Externí odkaz:
https://doaj.org/article/466af6325e8a43d29599ed36d486c4a4
Publikováno v:
Journal of the American Chemical Society. 136:6810-6813
Despite the widespread exploration of α-peptides as catalysts, there are few examples of β-peptides that alter the course of a chemical transformation. Our previous work demonstrated that a special class of β3-peptides spontaneously self-assembles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99e60c541d00ca9fd3771990d3168875
https://doi.org/10.1021/ja5013849
https://doi.org/10.1021/ja5013849
Autor:
Yorgo Modis, Jennifer B. Nguyen
Publikováno v:
Journal of Structural Biology. 181:82-88
LRRFIP1 binds cytoplasmic double-stranded DNA and RNA and interacts with FLI, the mammalian homolog of Drosophila flightless I, through a highly conserved 87-amino acid domain. Upon binding nucleic acid ligands, LRRFIP1 recruits and activates β-cate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf037f5146d44452dcff90313e40289
https://doi.org/10.1016/j.jsb.2012.10.006
https://doi.org/10.1016/j.jsb.2012.10.006
Publikováno v:
Journal of Biological Chemistry. 286:27622-27629
Rhodopsin has developed mechanisms to optimize its sensitivity to light by suppressing dark noise and enhancing quantum yield. We propose that an intramolecular hydrogen-bonding network formed by ∼20 water molecules, the hydrophilic residues, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2dc2cf685c6dca2697786c046b44f9
https://doi.org/10.1074/jbc.m111.233312
https://doi.org/10.1074/jbc.m111.233312
Publikováno v:
Journal of the American Chemical Society. 136(19)
Despite the widespread exploration of α-peptides as catalysts, there are few examples of β-peptides that alter the course of a chemical transformation. Our previous work demonstrated that a special class of β(3)-peptides spontaneously self-assembl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f0fce0c81ad2b93c4e1b4774901ea65
https://pubmed.ncbi.nlm.nih.gov/24802883
https://pubmed.ncbi.nlm.nih.gov/24802883
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 5 (2014)
Frontiers in Immunology, Vol 5 (2014)
Most organisms rely on innate immune receptors to recognize conserved molecular structures from invading microbes. Two essential innate immune receptors, RIG-I and MDA5, detect viral double-stranded RNA in the cytoplasm. The inflammatory response tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88736004074a73363f6b360b666ee44
https://pubmed.ncbi.nlm.nih.gov/25101084
https://pubmed.ncbi.nlm.nih.gov/25101084
Autor:
Cornelius Klöck, Richard H. G. Baxter, Jennifer B. Nguyen, Binh V. Le, Alexandra Schatz, Evdoxia G. Kakani, Chaitan Khosla, Flaminia Catteruccia
Publikováno v:
Malaria Journal
Background Current vector-based malaria control strategies are threatened by the rise of biochemical and behavioural resistance in mosquitoes. Researching mosquito traits of immunity and fertility is required to find potential targets for new vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f008e83c38dbf91d8db555a304562f77
http://hdl.handle.net/11391/1227679
http://hdl.handle.net/11391/1227679
Autor:
Darren F. Zhu, Jennifer B. Nguyen, Farren J. Isaacs, Peter L. Davies, Yorgo Modis, Koli Basu, Durga Thakral, Aaron Hakim, Wuyi Meng
Publikováno v:
The Journal of biological chemistry. 288(17)
Antifreeze proteins (AFPs) help some organisms resist freezing by binding to ice crystals and inhibiting their growth. The molecular basis for how these proteins recognize and bind ice is not well understood. The longhorn beetle Rhagium inquisitor ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0ffa179fe0baee1babdfbb6a8fa547
https://pubmed.ncbi.nlm.nih.gov/23486477
https://pubmed.ncbi.nlm.nih.gov/23486477